Click here to switch to the map view.

The map label for this gene is yjcR [H]

Identifier: 218692379

GI number: 218692379

Start: 4780473

End: 4781504

Strand: Reverse

Name: yjcR [H]

Synonym: ECED1_4816

Alternate gene names: 218692379

Gene position: 4781504-4780473 (Counterclockwise)

Preceding gene: 218692380

Following gene: 218692378

Centisome position: 91.78

GC content: 56.49

Gene sequence:

>1032_bases
ATGGAAAGTACGCCGAAAAAAGCTCCTCGCAGTAAATTCCCTGCTCTGTTAGTGGTTGCGTTGGCGCTGGTTGCCCTTGT
TTTCGTTATCTGGCGCGTAGACAGTGCGCCATCAACTAATGACGCTTACGCGTCAGCAGATACCATTGATGTGGTGCCGG
AAATCAGCGGTCGCATTGTTGAACTGGCGGTCACCGACAACCAAGCGGTGAAACAGGGCGATTTGCTGTTCCGCATTGAC
CCGCGCCCGTACGAAGCCAATCTGGCGAAAGCTGAAGCCTCCCTCGCGGCGCTGGATAAGCAAATTATGCTCACCCAGCG
TAGCGTTGACGCGCAACAGTTTGGTGCCGACTCGGTTAATGCCACGGTAGAAAAAGCCCGTGCCGCCGCGAAACAAGCCA
GCGATACGTTACGCCGTACCGAACCGCTACTGCGAGAAGGTTTTGTTTCTGCGGAAGAGGTTGACCGTGCAAGAACCGCA
CAGCGTGCGGCAGAAGCGGACCTTAATGCCGTATTGTTGCAGGCGCAGTCAGCCGCCAGCGCCGTCAGCGGCGTGGATGC
GCTGGTGGCGCAGCGTGCGGCAGTGGAAGCGGATATTGCCCTGACCAAACTGCATCTGGAAATGGCGACCGTTCGCGCGC
CGTTTGATGGCCGGGTCATTTCCCTCAAAACCTCCGTCGGGCAGTTTGCATCTGCGATGCGCCCTATTTTCACTCTAATC
GACACTCGTCACTGGTACGTGATTGCCAACTTCCGCGAAACTGATCTGAAAAATATTCGCTCGGGTACACCCGCAACCAT
TCGCCTGATGAGCGACAGCGGCAAAACCTTCGAGGGTAAAGTGGATTCGATTGGCTACGGCGTGCTACCGGATGACGGCG
GCCTGGTGCTGGGCGGCCTGCCGAAAGTGTCTCGTTCTATTAACTGGGTCCGCGTTGCCCAGCGTTTTCCGGTCAAAATC
ATGGTCGATAAACCTGACCCGGAAATGTTCCGCATCGGCGCTTCGGCAGTCGCTAATCTTGAGCCGCAATAA

Upstream 100 bases:

>100_bases
TATCAATCTGGCATTTGTCGGAATTATTTATACCGCCCTTTTTGCTCTCTACGCCATGCTGTTCTGGCTGGCATTTTTCT
AATCTATTTGAGACGCGCTC

Downstream 100 bases:

>100_bases
TGAGCGCGCTCAACTCCCTGCCATTACCGGTGGTCAGGCTGCTGGCGTTCTTTCATGAAGAGTTAAGCGAGCGGCGACCA
GGGCGCGTGCCACAGACGAT

Product: multidrug resistance protein MdtN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEISGRIVELAVTDNQAVKQGDLLFRID
PRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSVNATVEKARAAAKQASDTLRRTEPLLREGFVSAEEVDRARTA
QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKI
MVDKPDPEMFRIGASAVANLEPQ

Sequences:

>Translated_343_residues
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEISGRIVELAVTDNQAVKQGDLLFRID
PRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSVNATVEKARAAAKQASDTLRRTEPLLREGFVSAEEVDRARTA
QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKI
MVDKPDPEMFRIGASAVANLEPQ
>Mature_343_residues
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEISGRIVELAVTDNQAVKQGDLLFRID
PRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSVNATVEKARAAAKQASDTLRRTEPLLREGFVSAEEVDRARTA
QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKI
MVDKPDPEMFRIGASAVANLEPQ

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=343, Percent_Identity=98.8338192419825, Blast_Score=681, Evalue=0.0,
Organism=Escherichia coli, GI87081951, Length=318, Percent_Identity=32.3899371069182, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789637, Length=337, Percent_Identity=29.080118694362, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789041, Length=333, Percent_Identity=29.4294294294294, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788711, Length=352, Percent_Identity=27.2727272727273, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790012, Length=258, Percent_Identity=28.2945736434109, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790024, Length=254, Percent_Identity=26.3779527559055, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 36951; Mature: 36951

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEISGRIV
CCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCEEE
ELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSVN
EEEECCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHH
ATVEKARAAAKQASDTLRRTEPLLREGFVSAEEVDRARTAQRAAEADLNAVLLQAQSAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHEEEHHHHHH
AVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
HHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEECCCCCEEEEEECCHHHHHHHHHHHHHHH
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGL
CCCEEEEEEECCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEECC
PKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGASAVANLEPQ
HHHHHCCHHEEHHHHCCEEEEEECCCCHHEEECHHHHCCCCCC
>Mature Secondary Structure
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEISGRIV
CCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCEEE
ELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSVN
EEEECCCCHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHH
ATVEKARAAAKQASDTLRRTEPLLREGFVSAEEVDRARTAQRAAEADLNAVLLQAQSAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHEEEHHHHHH
AVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
HHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEECCCCCEEEEEECCHHHHHHHHHHHHHHH
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGL
CCCEEEEEEECCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEECC
PKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGASAVANLEPQ
HHHHHCCHHEEHHHHCCEEEEEECCCCHHEEECHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]