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The map label for this gene is zntR [H]

Identifier: 218691579

GI number: 218691579

Start: 3880093

End: 3880518

Strand: Reverse

Name: zntR [H]

Synonym: ECED1_3956

Alternate gene names: 218691579

Gene position: 3880518-3880093 (Counterclockwise)

Preceding gene: 218691580

Following gene: 218691578

Centisome position: 74.49

GC content: 49.77

Gene sequence:

>426_bases
ATGTATCGCATTGGTGAGCTGGCAAAAATGGCGGAAGTAACACCCGACACGATTCGTTATTACGAAAAGCAGCAGATGAT
GGAGCATGAAGTACGCACCGAAGGTGGGTTTCGCCTGTATACCAAAAGCGATCTCCAGCGATTGAAATTTATCCGCCATG
CCAGACAACTAGGTTTCAGTCTGGAGTCGATCCGCGAGTTGCTGTCGATCCGTATCGATCCGGAACACCATACCTGTCAG
GAGTCAAAAGGCATTGTGCAGGAACGATTGCAGGAAGTCGAAGCTCGTATAGCCGAGTTGCAGAGTATGCAGCGTTCCTT
GCAACGCCTTAATGATACCTGTTGTGGGACCGCCCATAGCAGTGTTTATTGCTCGATTCTTGAAGCTCTTGAACAAGGGG
CGAGTGGCGTTAAGAGTGGCTGTTGA

Upstream 100 bases:

>100_bases
GAATTGAAGCTGCGACAAGCTGGATTGAGTACCGATTTTTTACGCGGCGATTATGCTGACAAGTTGTTGAACAAAATCAA
CGATAACTAGTGGAGTATGT

Downstream 100 bases:

>100_bases
TTTTTTGCACTGGCAGGATTACACTCGCGCCGTTAAATAACCAACTGGAGTTTTTATGAGCCGATATCAGCATACTAAAG
GGCAGATAAAGGATAATGCG

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTKSDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQ
ESKGIVQERLQEVEARIAELQSMQRSLQRLNDTCCGTAHSSVYCSILEALEQGASGVKSGC

Sequences:

>Translated_141_residues
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTKSDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQ
ESKGIVQERLQEVEARIAELQSMQRSLQRLNDTCCGTAHSSVYCSILEALEQGASGVKSGC
>Mature_141_residues
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTKSDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQ
ESKGIVQERLQEVEARIAELQSMQRSLQRLNDTCCGTAHSSVYCSILEALEQGASGVKSGC

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=141, Percent_Identity=98.5815602836879, Blast_Score=285, Evalue=1e-78,
Organism=Escherichia coli, GI1786695, Length=138, Percent_Identity=36.9565217391304, Blast_Score=87, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16209; Mature: 16209

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTKSDLQRLKFIRHARQLGFS
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCC
LESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQSMQRSLQRLNDTCCGTAHS
HHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SVYCSILEALEQGASGVKSGC
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTKSDLQRLKFIRHARQLGFS
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCC
LESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQSMQRSLQRLNDTCCGTAHS
HHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SVYCSILEALEQGASGVKSGC
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]