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The map label for this gene is aapQ [H]

Identifier: 218691563

GI number: 218691563

Start: 3861673

End: 3862854

Strand: Direct

Name: aapQ [H]

Synonym: ECED1_3931

Alternate gene names: 218691563

Gene position: 3861673-3862854 (Clockwise)

Preceding gene: 218691562

Following gene: 218691564

Centisome position: 74.13

GC content: 49.75

Gene sequence:

>1182_bases
ATGTCTCATCGCCGCTCAACCGTTAAAGGCTCACTCTCTTTTGCCAACCCTACGGTTCGCGCCTGGTTATTCCAGATCCT
TGCCGTTGTTGCTGTTGTCGGCATTATTGGTTGGTTATTTCACAACACTGTAACGAATCTCAGTAATCGCGGCATAACAT
CAGGATTTGCTTTTCTTGACCGCGGGGCCGGTTTTGGCATCGTTCAGCATTTGATTGATTATCAGCAAGGCGACACTTAC
GGACGCGTTTTTATTGTCGGCCTGCTCAATACGCTACTGGTTTCTGCATTGTGTATTGTGTTCGCTTCTGTTTTGGGCTT
CTTTATCGGTCTGGCGAGACTTTCGGATAACTGGCTGCTACGAAAGCTTTCCACAATTTATATTGAGATCTTCCGTAATA
TTCCGCCATTGCTGCAAATCTTCTTCTGGTACTTTGCCGTGTTGCGCAATTTGCCCGGGCCACGCCAGGCAGTGAGCGCA
CTGGATTTGGTGTTTCTGAGCAATCGTGGGCTTTATATTCCGTCGCCGCAGCTGGGAGATGGGTTTCTTGCGTTTATCCT
GGCTGTTGTTATAGCTATAGTCCTTTCTGTTGGGCTATTCCGCTTTAATAAAACACACCAGATAAAGACCGGACAACTGC
GCCGCACCTGGCCGATTACCGCAGTGTTGATCATTGGTTTGCCTTTACTGGCGCAATGGCTTTTTGGCGCAGCACTACAC
TGGGATGTCCCAGCCCTTCGAGGCTTTAATTTCCGCGGCGGGATGGTTTTAATTCCTGAACTGGCAGCCTTAACGCTAGC
ACTTTCGATTTATACCTCTGCATTTATCGCCGAGATTATCCGAGCAGGGATCCAGGCAGTGCCTTATGGTCAACATGAAG
CGGCTCGATCACTGGGATTACCCAACCCGGTAACGCTACGCCGGGTCATTATTCCCCAGGCATTGCGGGTGATTATTCCA
CCGTTAACCAGCCAGTATCTCAACATCGTCAAGAACTCCTCTCTTGCCGCCGCTATTGGCTATCCCGATATGGTTTCGCT
GTTTGCTGGCACCGTGCTGAACCAAACGGGGCAAGCCATCGAGACGATAGCCATGACCATGTCGGTCTATCTGATTATCA
GCCTGACTATCTCGCTGCTGATGAATATCTATAACCGCCGCATCGCGATCGTTGAACGCTAA

Upstream 100 bases:

>100_bases
GGCGGTATTCAGTACGCGCCGCCCGTGCGTTAAGTCGGTGTGAGGTAACGAGCGTCGCTACGGCGGCGCTCTCTTCAGCG
TTATGCTTTCCGAGGTTTCT

Downstream 100 bases:

>100_bases
GGAGTCATGATGACAAAAGTATTGCTGTCTCATCCCCCGCGCCCGGCGAGCCATAACTCAAGCCGCGCGATGGTGTGGGT
GCGAAAAAATCTGTTCTCCA

Product: amino-acid ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIIGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
LDLVFLSNRGLYIPSPQLGDGFLAFILAVVIAIVLSVGLFRFNKTHQIKTGQLRRTWPITAVLIIGLPLLAQWLFGAALH
WDVPALRGFNFRGGMVLIPELAALTLALSIYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRRVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER

Sequences:

>Translated_393_residues
MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIIGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
LDLVFLSNRGLYIPSPQLGDGFLAFILAVVIAIVLSVGLFRFNKTHQIKTGQLRRTWPITAVLIIGLPLLAQWLFGAALH
WDVPALRGFNFRGGMVLIPELAALTLALSIYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRRVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
>Mature_392_residues
SHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIIGWLFHNTVTNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYG
RVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSAL
DLVFLSNRGLYIPSPQLGDGFLAFILAVVIAIVLSVGLFRFNKTHQIKTGQLRRTWPITAVLIIGLPLLAQWLFGAALHW
DVPALRGFNFRGGMVLIPELAALTLALSIYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRRVIIPQALRVIIPP
LTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=393, Percent_Identity=97.4554707379135, Blast_Score=744, Evalue=0.0,
Organism=Escherichia coli, GI1786874, Length=123, Percent_Identity=39.8373983739837, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788226, Length=171, Percent_Identity=35.672514619883, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786873, Length=124, Percent_Identity=35.4838709677419, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082239, Length=120, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787030, Length=134, Percent_Identity=32.089552238806, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788645, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787087, Length=128, Percent_Identity=27.34375, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43271; Mature: 43140

Theoretical pI: Translated: 11.06; Mature: 11.06

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
>Mature Secondary Structure 
SHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIIGWLFHNTVTNLSNRGITSGFAFLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RGAGFGIVQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSALDLVFLSNRGLYIPSPQLGD
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCCCCCC
GFLAFILAVVIAIVLSVGLFRFNKTHQIKTGQLRRTWPITAVLIIGLPLLAQWLFGAALH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
WDVPALRGFNFRGGMVLIPELAALTLALSIYTSAFIAEIIRAGIQAVPYGQHEAARSLGL
CCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
PNPVTLRRVIIPQALRVIIPPLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAI
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHH
ETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]