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The map label for this gene is aapM [H]

Identifier: 218691564

GI number: 218691564

Start: 3862864

End: 3863967

Strand: Direct

Name: aapM [H]

Synonym: ECED1_3932

Alternate gene names: 218691564

Gene position: 3862864-3863967 (Clockwise)

Preceding gene: 218691563

Following gene: 218691565

Centisome position: 74.15

GC content: 51.63

Gene sequence:

>1104_bases
ATGACAAAAGTATTGCTGTCTCATCCCCCGCGCCCGGCGAGCCATAACTCAAGCCGCGCGATGGTGTGGGTGCGAAAAAA
TCTGTTCTCCAGCTGGAGCAATAGCCTGCTGACTATTGGCTGCATATGGTTGATGTGGGAACTGATCCCACCATTGCTGA
ACTGGGCATTTTTGCAGGCTAACTGGGTTGGCTCAACGCGTGCCGACTGCACAAAAGCCGGTGCCTGTTGGGTCTTCATC
CACGAACGATTTGGTCAGTTTATATATGGACTTTACCCACACGACCAACGCTGGCGAATTAACCTGGCATTACTGATTGG
CCTTGTGTCTATCGCACCAATGTTCTGGAAAATACTTCCGCATCGCGGTCGCTATATTGCGGTCTGGGCGGTGATTTACC
CACTGGTTGTCTGGTGGCTGATGTATGGCGGGTTTCTTGGTCTTGATCGGGTTGAAACCCGGCAATGGGGCGGGTTGACG
CTAACTTTAATTATTGCATCAGTTGGGATTGCGGGGGCGCTACCGTGGGGGATCTTACTGGCGTTAGGTCGCCGCTCCCA
TATGCCGATTGTGCGTATCTTATCGGTCATTTTTATCGAGTTCTGGCGCGGCGTACCGCTGATTACCGTATTGTTTATGT
CTTCGGTCATGCTGCCGTTGTTTATGGCAGAAGGCACCAGTATCGACAAACTAATCCGCGCGCTGGTTGGCGTGATCCTG
TTTCAGTCAGCATATGTTGCGGAAGTCGTGCGAGGCGGATTACAGGCGCTGCCTAAAGGGCAATATGAAGCGGCAGAGTC
GCTGGCATTGGGTTACTGGAAAACTCAGGGGCTTGTTATTCTGCCACAGGCGTTGAAGCTGGTAATTCCTGGGCTGGTAA
ATACCATCATCGCACTCTTCAAAGATACCAGCCTGGTGATCATCATCGGGTTGTTCGATCTTTTCAGTAGCGTTCAGCAG
GCAACCGTTGATCCCGCCTGGTTGGGTATGTCGACGGAAGGGTATGTTTTCGCCGCGCTGATCTACTGGATCTTCTGTTT
CAGCATGTCACGTTATAGCCAACATCTGGAAAAATGTTTTAACACCGGGCGTACACCGCATTGA

Upstream 100 bases:

>100_bases
CATGACCATGTCGGTCTATCTGATTATCAGCCTGACTATCTCGCTGCTGATGAATATCTATAACCGCCGCATCGCGATCG
TTGAACGCTAAGGAGTCATG

Downstream 100 bases:

>100_bases
GGACACTATGAGCCAAATTTTACTGCAACCTGCTAACGCGATGATTACGCTGGAAAACGTCAATAAATGGTATGGACAAT
TCCATGTTTTGAAAAATATA

Product: amino-acid ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFI
HERFGQFIYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLVVWWLMYGGFLGLDRVETRQWGGLT
LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQ
ATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKCFNTGRTPH

Sequences:

>Translated_367_residues
MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFI
HERFGQFIYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLVVWWLMYGGFLGLDRVETRQWGGLT
LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQ
ATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKCFNTGRTPH
>Mature_366_residues
TKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIH
ERFGQFIYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLVVWWLMYGGFLGLDRVETRQWGGLTL
TLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVILF
QSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQA
TVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKCFNTGRTPH

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=367, Percent_Identity=97.8201634877384, Blast_Score=725, Evalue=0.0,
Organism=Escherichia coli, GI1788226, Length=212, Percent_Identity=38.6792452830189, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1786873, Length=207, Percent_Identity=30.9178743961353, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787030, Length=201, Percent_Identity=31.8407960199005, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI48994930, Length=111, Percent_Identity=35.1351351351351, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788645, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786874, Length=131, Percent_Identity=28.2442748091603, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787087, Length=171, Percent_Identity=29.8245614035088, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41340; Mature: 41209

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQA
CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEE
NWVGSTRADCTKAGACWVFIHERFGQFIYGLYPHDQRWRINLALLIGLVSIAPMFWKILP
CCCCCCCCHHHCCCCCEEHHHHHHHHHEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCC
HRGRYIAVWAVIYPLVVWWLMYGGFLGLDRVETRQWGGLTLTLIIASVGIAGALPWGILL
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
HHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHHHHH
KDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKCF
CCCCCEEHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NTGRTPH
HCCCCCC
>Mature Secondary Structure 
TKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQA
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEE
NWVGSTRADCTKAGACWVFIHERFGQFIYGLYPHDQRWRINLALLIGLVSIAPMFWKILP
CCCCCCCCHHHCCCCCEEHHHHHHHHHEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCC
HRGRYIAVWAVIYPLVVWWLMYGGFLGLDRVETRQWGGLTLTLIIASVGIAGALPWGILL
CCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
HHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHHHHH
KDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKCF
CCCCCEEHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NTGRTPH
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]