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The map label for this gene is nanR [H]

Identifier: 218691509

GI number: 218691509

Start: 3807913

End: 3808704

Strand: Reverse

Name: nanR [H]

Synonym: ECED1_3877

Alternate gene names: 218691509

Gene position: 3808704-3807913 (Counterclockwise)

Preceding gene: 218691510

Following gene: 218691508

Centisome position: 73.11

GC content: 53.41

Gene sequence:

>792_bases
ATGAGTCCTATGAACGCATTTGATCCGCAAGCTGAAGATTCTACTACCACTATCGGGCGCAACTTGCGCAGCCGCCCGCT
GGCGCGTAAAAAACTCTCCGAAATGGTGGAAGAAGAGCTGGAACAGATGATCCGCCGTCGTGAATTTGGTGAAGGTGAAC
AATTACCGTCTGAACGCGAACTGATGGCGTTCTTTAACGTCGGGCGTCCTTCGGTGCGCGAAGCGCTGGCAGCGTTAAAA
CGCAAAGGTCTGGTGCAAATAAACAACGGCGAACGTGCCCGCGTCTCACGTCCTTCTGCGGACACCATCATCGGCGAGCT
TTCCGGCATGGCGAAAGATTTCCTTTCTCATCCTGGTGGGATTGCCCATTTCGAACAATTACGTCTGTTCTTTGAATCCA
GCCTGGTGCGCTATGCGGCTGAACACGCCACCGATGAGCAAATCGATTTGCTGGCAAAAGCACTGGAAATCAACAGTCAG
TCGCTGGATAACAACGCGGCATTCATTCGCTCAGACGTTGATTTCCACCGCGTTCTGGCGGAGATCCCTGGTAACCCAAT
CTTCATGGCGATCCACGTTGCCCTGCTCGACTGGCTAATCGCCGCACGTCCAACCGTGGCCGATCAGGCTCTGCATGAGC
ATAACAACGTTAGCTATCAACAGCATATTGCGATCGTTGACGCGATCCGCCGTCATGATCCTGACGAAGCCGATCGCGCG
TTGCAATCGCATCTCAACAGCGTCTCTGCTACCTGGCACGCCTTCGGTCAGACCACCAACAAAAAGAAATAA

Upstream 100 bases:

>100_bases
ACAGGCCCATGTGGCCTGTTTTGCTATCTGTCATCTTTTCGCCTGACTTTGATACTGTGCTACGATAGCGTCGTTATTAT
CCGCTAACGCATTTTCCTGA

Downstream 100 bases:

>100_bases
TGCCACTTTAGTGAAGCAGATCGCATTATAAGCTTTCTGTATGGGGTGTTGCTTAATTGATCTGGTATAACAGGTATAAA
GGTATATCGTTTATCAGACA

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSPMNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALK
RKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRA
LQSHLNSVSATWHAFGQTTNKKK

Sequences:

>Translated_263_residues
MSPMNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALK
RKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRA
LQSHLNSVSATWHAFGQTTNKKK
>Mature_262_residues
SPMNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKR
KGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQS
LDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRAL
QSHLNSVSATWHAFGQTTNKKK

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=263, Percent_Identity=96.958174904943, Blast_Score=520, Evalue=1e-149,
Organism=Escherichia coli, GI1789353, Length=232, Percent_Identity=22.8448275862069, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29537; Mature: 29405

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPMNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERE
CCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGG
HHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
IAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHH
EIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRA
HCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHH
LQSHLNSVSATWHAFGQTTNKKK
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SPMNAFDPQAEDSTTTIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERE
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGG
HHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
IAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHH
EIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRA
HCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHH
LQSHLNSVSATWHAFGQTTNKKK
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA