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The map label for this gene is yjjN [H]

Identifier: 218691310

GI number: 218691310

Start: 3595825

End: 3596841

Strand: Direct

Name: yjjN [H]

Synonym: ECED1_3670

Alternate gene names: 218691310

Gene position: 3595825-3596841 (Clockwise)

Preceding gene: 218691309

Following gene: 218691311

Centisome position: 69.02

GC content: 47.3

Gene sequence:

>1017_bases
ATGAAAACATTAATTTGTCAGCAGCCTGGCGTTATGGAATATGTGGAAAAGGATATTCCCACACCAGCAGATAATGAAGT
GCTGTTAAAAATCAAAGCTGTGGGTATTTGTGGTACTGATATTCACGCTTTTGCCGGCAGACAGCCTTTTTTTAGCTACC
CACGTGTATTAGGTCATGAAATATGCGCCGAAGCGGTTTCGCGAGGCAGCCAGAGCCAAACAGCACAATCAGGCCAGCGC
TATTCCGTCATCCCATGCATTCCGTGTGGCGAGTGCGCAGCCTGTCGGGAAGAGAAAACGAACTGCTGCGAACGTGTTTC
GCTGTATGGCGTGCATCAGGATGGGGGTTTTAGTGAGTACCTTGCGGTACGTGAAGACAACCTTGTGCCTCTCCCTGACG
AGGTCAGCGACAGTGCCGGAGCATTGGTTGAATGTTTCGCCATTGGTGCACATGCCGTTCGTCGGGCAGAGATCAAGGCT
GAACAAAACGTACTGGTGATTGGCGCTGGGCCAATCGGTCTGGCTACCGCGGCCATCGCCAGGGCTAAAGGGGCGCATGT
TGTTGTTGCTGATATTGATTGTCAACGTCGCCAGCACGTTGTGGATCATCTGGCGATTAATGTCTTCGACCCAACACAGG
AAGGTTTTATTGCCGCGCTTAGTGAAGTGTTTGGCGGCGAACTGGCTTGCGTAGTACTGGATGCGACGGGAAATAAAGCT
TCAATGAGTCAGGATGTAAATCTTATTCGTCATGGCGGCAAAATTGTTTTCATCGGTTTATACATTGGTGAACTTGTTAT
TGACGATCCGACCTTCCATAAAAAAGAGACAACTTTACTCAGCAGTCGCAATGCCACACGGGAAGATTTTGCGTTGGTGA
TTGAACTGATGCGCAGCAATAAAATTCACGAAAATTTAATGAAAAACCAGGAGTTCGATTTCTTTAGTGTTGGCGAAGAT
TACCAACGTAACGTTGTAGAAAATAAAAATATGGTCAAGGGTGTGATCACTTTTTAA

Upstream 100 bases:

>100_bases
ACCATCAGCCATTTATAAATGAAATAAAAATCGCCTTTGCAAATATAAAAAACAAAGGCATCAAGGCCACCATCAGCCAA
TTATTATCGGATGAGCAGAA

Downstream 100 bases:

>100_bases
GGGAACAAATATGACAACTGTTTATGTCAGTGAAGAAAATTTAAAATCACTGGTGCACCACAAATTACATACCGCCGGGC
TGGATGCCGATACCGCACAA

Product: putative L-threonine 3-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKTLICQQPGVMEYVEKDIPTPADNEVLLKIKAVGICGTDIHAFAGRQPFFSYPRVLGHEICAEAVSRGSQSQTAQSGQR
YSVIPCIPCGECAACREEKTNCCERVSLYGVHQDGGFSEYLAVREDNLVPLPDEVSDSAGALVECFAIGAHAVRRAEIKA
EQNVLVIGAGPIGLATAAIARAKGAHVVVADIDCQRRQHVVDHLAINVFDPTQEGFIAALSEVFGGELACVVLDATGNKA
SMSQDVNLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFALVIELMRSNKIHENLMKNQEFDFFSVGED
YQRNVVENKNMVKGVITF

Sequences:

>Translated_338_residues
MKTLICQQPGVMEYVEKDIPTPADNEVLLKIKAVGICGTDIHAFAGRQPFFSYPRVLGHEICAEAVSRGSQSQTAQSGQR
YSVIPCIPCGECAACREEKTNCCERVSLYGVHQDGGFSEYLAVREDNLVPLPDEVSDSAGALVECFAIGAHAVRRAEIKA
EQNVLVIGAGPIGLATAAIARAKGAHVVVADIDCQRRQHVVDHLAINVFDPTQEGFIAALSEVFGGELACVVLDATGNKA
SMSQDVNLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFALVIELMRSNKIHENLMKNQEFDFFSVGED
YQRNVVENKNMVKGVITF
>Mature_338_residues
MKTLICQQPGVMEYVEKDIPTPADNEVLLKIKAVGICGTDIHAFAGRQPFFSYPRVLGHEICAEAVSRGSQSQTAQSGQR
YSVIPCIPCGECAACREEKTNCCERVSLYGVHQDGGFSEYLAVREDNLVPLPDEVSDSAGALVECFAIGAHAVRRAEIKA
EQNVLVIGAGPIGLATAAIARAKGAHVVVADIDCQRRQHVVDHLAINVFDPTQEGFIAALSEVFGGELACVVLDATGNKA
SMSQDVNLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFALVIELMRSNKIHENLMKNQEFDFFSVGED
YQRNVVENKNMVKGVITF

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=279, Percent_Identity=31.8996415770609, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI262073058, Length=216, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI71743840, Length=216, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4501939, Length=234, Percent_Identity=23.5042735042735, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI156523966, Length=234, Percent_Identity=23.5042735042735, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI194239674, Length=280, Percent_Identity=22.8571428571429, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI13236495, Length=280, Percent_Identity=22.8571428571429, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4501929, Length=213, Percent_Identity=30.5164319248826, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI226510992, Length=338, Percent_Identity=55.6213017751479, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1787863, Length=343, Percent_Identity=31.4868804664723, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1788073, Length=342, Percent_Identity=30.9941520467836, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082125, Length=276, Percent_Identity=31.8840579710145, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790045, Length=257, Percent_Identity=31.1284046692607, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788407, Length=287, Percent_Identity=27.5261324041812, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790718, Length=308, Percent_Identity=27.5974025974026, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786825, Length=315, Percent_Identity=26.6666666666667, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788075, Length=347, Percent_Identity=26.8011527377522, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786552, Length=228, Percent_Identity=30.7017543859649, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081918, Length=306, Percent_Identity=25.1633986928105, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082401, Length=138, Percent_Identity=31.1594202898551, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=318, Percent_Identity=28.6163522012579, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562878, Length=228, Percent_Identity=31.140350877193, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71988145, Length=256, Percent_Identity=30.46875, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562584, Length=321, Percent_Identity=25.5451713395639, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562582, Length=339, Percent_Identity=25.9587020648968, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322619, Length=347, Percent_Identity=28.5302593659942, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319955, Length=347, Percent_Identity=28.5302593659942, Blast_Score=133, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6323099, Length=345, Percent_Identity=27.8260869565217, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319257, Length=314, Percent_Identity=27.0700636942675, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319258, Length=232, Percent_Identity=28.0172413793103, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319621, Length=261, Percent_Identity=27.2030651340996, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=277, Percent_Identity=27.0758122743682, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=290, Percent_Identity=27.2413793103448, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=289, Percent_Identity=26.9896193771626, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323980, Length=259, Percent_Identity=27.7992277992278, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=266, Percent_Identity=24.812030075188, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17137530, Length=225, Percent_Identity=34.2222222222222, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI17737897, Length=186, Percent_Identity=38.1720430107527, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550770, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221457811, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551930, Length=187, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737895, Length=202, Percent_Identity=27.7227722772277, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36825; Mature: 36825

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLICQQPGVMEYVEKDIPTPADNEVLLKIKAVGICGTDIHAFAGRQPFFSYPRVLGHE
CCCEECCCCCHHHHHHHCCCCCCCCCEEEEEEEEEEECCCHHHHCCCCCCHHHHHHHHHH
ICAEAVSRGSQSQTAQSGQRYSVIPCIPCGECAACREEKTNCCERVSLYGVHQDGGFSEY
HHHHHHHCCCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHH
LAVREDNLVPLPDEVSDSAGALVECFAIGAHAVRRAEIKAEQNVLVIGAGPIGLATAAIA
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
RAKGAHVVVADIDCQRRQHVVDHLAINVFDPTQEGFIAALSEVFGGELACVVLDATGNKA
HCCCCEEEEECCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCC
SMSQDVNLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFALVIELMRSN
HHHHHHHHHHCCCEEEEEEEEECEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCC
KIHENLMKNQEFDFFSVGEDYQRNVVENKNMVKGVITF
CHHHHHHCCCCCCEEECCCHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure
MKTLICQQPGVMEYVEKDIPTPADNEVLLKIKAVGICGTDIHAFAGRQPFFSYPRVLGHE
CCCEECCCCCHHHHHHHCCCCCCCCCEEEEEEEEEEECCCHHHHCCCCCCHHHHHHHHHH
ICAEAVSRGSQSQTAQSGQRYSVIPCIPCGECAACREEKTNCCERVSLYGVHQDGGFSEY
HHHHHHHCCCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHH
LAVREDNLVPLPDEVSDSAGALVECFAIGAHAVRRAEIKAEQNVLVIGAGPIGLATAAIA
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
RAKGAHVVVADIDCQRRQHVVDHLAINVFDPTQEGFIAALSEVFGGELACVVLDATGNKA
HCCCCEEEEECCCHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCC
SMSQDVNLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFALVIELMRSN
HHHHHHHHHHCCCEEEEEEEEECEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCC
KIHENLMKNQEFDFFSVGEDYQRNVVENKNMVKGVITF
CHHHHHHCCCCCCEEECCCHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]