Click here to switch to the map view.

The map label for this gene is yjmC [H]

Identifier: 218691311

GI number: 218691311

Start: 3596852

End: 3597862

Strand: Direct

Name: yjmC [H]

Synonym: ECED1_3671

Alternate gene names: 218691311

Gene position: 3596852-3597862 (Clockwise)

Preceding gene: 218691310

Following gene: 218691312

Centisome position: 69.04

GC content: 47.38

Gene sequence:

>1011_bases
ATGACAACTGTTTATGTCAGTGAAGAAAATTTAAAATCACTGGTGCACCACAAATTACATACCGCCGGGCTGGATGCCGA
TACCGCACAACAGGTGACAGATGTTTTGGTACATGCCGATATTACCGGTGTGCATTCACATGGAGTTATGCGTGTTGAAC
ATTATTGCACACGCCTTGCTGCCGGAGGGTTAAATAAAGCCCCGCAGTTTAGCATTGAGCAAATTTCACCGTCAGTGGCT
ATTCTCGACTCTGACGACGGAATGGGGCATTCGGCATTAATTAGCGCCACTGAGCACGTCATTAAACTGGCCCAGCAAGA
GGGCCTCGGTTTTGTTAGCGTTAAAAACACGTCTCACTGTGGTGCATTATCTTATTTTGCAGAGATGATCACCAACAAAG
GGTTGGTTGCTATTGTAATGACGCAAACCGATACCTGCGTGGCTCCTCATGGCGGCGCCGAGCGCTTTTTGGGTACTAAC
CCCATCGCCTTCGGTTTCCCGGTGGAAAACAGCCATCCGATGATTGTTGATATGGCGACCAGTGCCACGGCTTTCGGCAA
AATACTTCATGCAAAGGAAACCGGAAAACATATTGGTGAAGGGCTGGCGATAGATAAAGATGGTTATGGCACCACTGATC
CGCATAAGATTGAAAACCTGCTACCTTTCGGCCAACACAAAGGTTCAGGCATTGCGCTGGCTATTGATGCACTGACTGGC
GTGCTGATGAATGCGAATTTTGGTAACCATATTGTTCGCATGTATGGTGATTATGACAAGATGCGTAAGCTGGCAAGTTT
GGTTATTGCCATCGATCCGAAAAAGCTCGGCAATCCTGTTTTTGCAAAAACTATGGCGCAAATGGTCACGGAACTGCATG
CCGTTAAACCGGTTCCCGGTGTCGAAAAAGTGTTAGCGCCGAACGATCCGCAAATGCACTACAAAGAAAAATGCCAGCAG
GAAGGTATTCCGGTTCCGGCAGGAATATTCCATTATCTGGCAGAGAATTAA

Upstream 100 bases:

>100_bases
CAGGAGTTCGATTTCTTTAGTGTTGGCGAAGATTACCAACGTAACGTTGTAGAAAATAAAAATATGGTCAAGGGTGTGAT
CACTTTTTAAGGGAACAAAT

Downstream 100 bases:

>100_bases
TCACTATTTTTTATTATAACGATAGAAAAGCGCTGTATTTATCGTTTCTGTTATATTAACCAGGAGCAGGATATGAAAGC
ACTTCGTCCTCTGACGGCAT

Product: Ureidoglycolate dehydrogenase

Products: oxalureate; NADH; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTTVYVSEENLKSLVHHKLHTAGLDADTAQQVTDVLVHADITGVHSHGVMRVEHYCTRLAAGGLNKAPQFSIEQISPSVA
ILDSDDGMGHSALISATEHVIKLAQQEGLGFVSVKNTSHCGALSYFAEMITNKGLVAIVMTQTDTCVAPHGGAERFLGTN
PIAFGFPVENSHPMIVDMATSATAFGKILHAKETGKHIGEGLAIDKDGYGTTDPHKIENLLPFGQHKGSGIALAIDALTG
VLMNANFGNHIVRMYGDYDKMRKLASLVIAIDPKKLGNPVFAKTMAQMVTELHAVKPVPGVEKVLAPNDPQMHYKEKCQQ
EGIPVPAGIFHYLAEN

Sequences:

>Translated_336_residues
MTTVYVSEENLKSLVHHKLHTAGLDADTAQQVTDVLVHADITGVHSHGVMRVEHYCTRLAAGGLNKAPQFSIEQISPSVA
ILDSDDGMGHSALISATEHVIKLAQQEGLGFVSVKNTSHCGALSYFAEMITNKGLVAIVMTQTDTCVAPHGGAERFLGTN
PIAFGFPVENSHPMIVDMATSATAFGKILHAKETGKHIGEGLAIDKDGYGTTDPHKIENLLPFGQHKGSGIALAIDALTG
VLMNANFGNHIVRMYGDYDKMRKLASLVIAIDPKKLGNPVFAKTMAQMVTELHAVKPVPGVEKVLAPNDPQMHYKEKCQQ
EGIPVPAGIFHYLAEN
>Mature_335_residues
TTVYVSEENLKSLVHHKLHTAGLDADTAQQVTDVLVHADITGVHSHGVMRVEHYCTRLAAGGLNKAPQFSIEQISPSVAI
LDSDDGMGHSALISATEHVIKLAQQEGLGFVSVKNTSHCGALSYFAEMITNKGLVAIVMTQTDTCVAPHGGAERFLGTNP
IAFGFPVENSHPMIVDMATSATAFGKILHAKETGKHIGEGLAIDKDGYGTTDPHKIENLLPFGQHKGSGIALAIDALTGV
LMNANFGNHIVRMYGDYDKMRKLASLVIAIDPKKLGNPVFAKTMAQMVTELHAVKPVPGVEKVLAPNDPQMHYKEKCQQE
GIPVPAGIFHYLAEN

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=329, Percent_Identity=40.1215805471125, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1787020, Length=334, Percent_Identity=27.5449101796407, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790000, Length=277, Percent_Identity=26.7148014440433, Blast_Score=101, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17507179, Length=331, Percent_Identity=27.7945619335347, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17536633, Length=329, Percent_Identity=25.2279635258359, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI45553211, Length=315, Percent_Identity=31.1111111111111, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24667912, Length=315, Percent_Identity=31.1111111111111, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24667908, Length=315, Percent_Identity=31.1111111111111, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24667904, Length=315, Percent_Identity=31.1111111111111, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24658010, Length=329, Percent_Identity=25.8358662613982, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24648360, Length=319, Percent_Identity=24.7648902821317, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.154

Molecular weight: Translated: 36013; Mature: 35882

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVYVSEENLKSLVHHKLHTAGLDADTAQQVTDVLVHADITGVHSHGVMRVEHYCTRLA
CEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AGGLNKAPQFSIEQISPSVAILDSDDGMGHSALISATEHVIKLAQQEGLGFVSVKNTSHC
HCCCCCCCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
GALSYFAEMITNKGLVAIVMTQTDTCVAPHGGAERFLGTNPIAFGFPVENSHPMIVDMAT
HHHHHHHHHHCCCCEEEEEEECCCCEECCCCCHHHHCCCCCEEEECCCCCCCCEEEEECC
SATAFGKILHAKETGKHIGEGLAIDKDGYGTTDPHKIENLLPFGQHKGSGIALAIDALTG
CHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHCCCCCCCCCCCEEEEHHHHHH
VLMNANFGNHIVRMYGDYDKMRKLASLVIAIDPKKLGNPVFAKTMAQMVTELHAVKPVPG
HHHCCCCCCCEEEEECCHHHHHHHHHHEEEECHHHHCCHHHHHHHHHHHHHHHHCCCCCC
VEKVLAPNDPQMHYKEKCQQEGIPVPAGIFHYLAEN
HHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TTVYVSEENLKSLVHHKLHTAGLDADTAQQVTDVLVHADITGVHSHGVMRVEHYCTRLA
EEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AGGLNKAPQFSIEQISPSVAILDSDDGMGHSALISATEHVIKLAQQEGLGFVSVKNTSHC
HCCCCCCCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
GALSYFAEMITNKGLVAIVMTQTDTCVAPHGGAERFLGTNPIAFGFPVENSHPMIVDMAT
HHHHHHHHHHCCCCEEEEEEECCCCEECCCCCHHHHCCCCCEEEECCCCCCCCEEEEECC
SATAFGKILHAKETGKHIGEGLAIDKDGYGTTDPHKIENLLPFGQHKGSGIALAIDALTG
CHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHCCCCCCCCCCCEEEEHHHHHH
VLMNANFGNHIVRMYGDYDKMRKLASLVIAIDPKKLGNPVFAKTMAQMVTELHAVKPVPG
HHHCCCCCCCEEEEECCHHHHHHHHHHEEEECHHHHCCHHHHHHHHHHHHHHHHCCCCCC
VEKVLAPNDPQMHYKEKCQQEGIPVPAGIFHYLAEN
HHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-ureidoglycolate; NAD+; NADP+

Specific reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]