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The map label for this gene is kpsM [H]

Identifier: 218691245

GI number: 218691245

Start: 3524802

End: 3525638

Strand: Reverse

Name: kpsM [H]

Synonym: ECED1_3602

Alternate gene names: 218691245

Gene position: 3525638-3524802 (Counterclockwise)

Preceding gene: 218691246

Following gene: 218691244

Centisome position: 67.68

GC content: 44.92

Gene sequence:

>837_bases
TTGGTAGCTGTTAAGCCAAGGGCGGTAGCGTACCTGAAGAGATTAGGATCACATCATCAAATGGCAAGAAGTGGATTTGA
AGTCCAGAAAGTCACCGTAGAGGCATTATTTCTACGAGAAATACGAACACGCTTTGGTAAGTTCCGTCTGGGATATCTGT
GGGCGATTCTCGAACCCTCTGCGCATTTGCTGATACTGTTGGGCATTTTTGGTTACATTATGCACCGCACGATGCCAGAC
ATCTCATTCCCGGTGTTTTTACTTAATGGCCTGATTCCCTTTTTTATCTTTAGCAGTATCAGCAATCGTTCTGTAGGTGC
TATTGAAGCGAATCAGGGGCTGTTTAATTATCGACCAGTAAAACCCATCGATACGATCATTGCGCGCGCCCTGCTTGAGA
CGCTGATTTACGTTGCTGTTTATATTCTGCTTATGCTTATCGTCTGGATGGCAGGCGAATATTTCGAGATAACAAATTTT
TTACAACTTGTGCTCACCTGGAGTTTGTTAATCATTCTTTCATGTGGCGTCGGCTTAATATTCATGGTCGTTGGTAAGAC
TTTCCCTGAAATGCAAAAGGTCCTGCCGATACTGCTTAAGCCGCTGTATTTCATCTCCTGCATCATGTTCCCTCTGCACT
CAATTCCAAAGCAATACTGGTCATATCTACTCTGGAACCCATTAGTGCATGTCGTAGAGTTAAGCCGCGAGGCAGTTATG
CCTGGCTATATCAGCGAAGGCGTTAGTCTGAACTACCTTGCAATGTTCACTCTGGTCACCCTGTTCATCGGTCTGGCTTT
ATACCTAACGCGTGAAGAGGCAATGCTGACATCATGA

Upstream 100 bases:

>100_bases
TGCGGAAATAATTTCTGCTGAAATTTTTTGCGGCTATTAAAAAGGTCAAACCGTCTGAGTAAATTTTATCCAGTTACAAA
TAAGCATTACCTCCAGTGTA

Downstream 100 bases:

>100_bases
TTAAGATTGAAAATTTGACGAAGTCATATCGCACGCCAGCGGGTCGACATTATGTCTTTAAGGATTTAAATATTGAAATC
CCTTCAGGAAAAAGTGTTGC

Product: Polysialic acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MVAVKPRAVAYLKRLGSHHQMARSGFEVQKVTVEALFLREIRTRFGKFRLGYLWAILEPSAHLLILLGIFGYIMHRTMPD
ISFPVFLLNGLIPFFIFSSISNRSVGAIEANQGLFNYRPVKPIDTIIARALLETLIYVAVYILLMLIVWMAGEYFEITNF
LQLVLTWSLLIILSCGVGLIFMVVGKTFPEMQKVLPILLKPLYFISCIMFPLHSIPKQYWSYLLWNPLVHVVELSREAVM
PGYISEGVSLNYLAMFTLVTLFIGLALYLTREEAMLTS

Sequences:

>Translated_278_residues
MVAVKPRAVAYLKRLGSHHQMARSGFEVQKVTVEALFLREIRTRFGKFRLGYLWAILEPSAHLLILLGIFGYIMHRTMPD
ISFPVFLLNGLIPFFIFSSISNRSVGAIEANQGLFNYRPVKPIDTIIARALLETLIYVAVYILLMLIVWMAGEYFEITNF
LQLVLTWSLLIILSCGVGLIFMVVGKTFPEMQKVLPILLKPLYFISCIMFPLHSIPKQYWSYLLWNPLVHVVELSREAVM
PGYISEGVSLNYLAMFTLVTLFIGLALYLTREEAMLTS
>Mature_278_residues
MVAVKPRAVAYLKRLGSHHQMARSGFEVQKVTVEALFLREIRTRFGKFRLGYLWAILEPSAHLLILLGIFGYIMHRTMPD
ISFPVFLLNGLIPFFIFSSISNRSVGAIEANQGLFNYRPVKPIDTIIARALLETLIYVAVYILLMLIVWMAGEYFEITNF
LQLVLTWSLLIILSCGVGLIFMVVGKTFPEMQKVLPILLKPLYFISCIMFPLHSIPKQYWSYLLWNPLVHVVELSREAVM
PGYISEGVSLNYLAMFTLVTLFIGLALYLTREEAMLTS

Specific function: KpsM and kpsT constitute a system for the transport of polysialic acid across the cytoplasmic membrane [H]

COG id: COG1682

COG function: function code GM; ABC-type polysaccharide/polyol phosphate export systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000412
- InterPro:   IPR013526
- InterPro:   IPR013525 [H]

Pfam domain/function: PF01061 ABC2_membrane [H]

EC number: NA

Molecular weight: Translated: 31749; Mature: 31749

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS51012 ABC_TM2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVKPRAVAYLKRLGSHHQMARSGFEVQKVTVEALFLREIRTRFGKFRLGYLWAILEPS
CCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
AHLLILLGIFGYIMHRTMPDISFPVFLLNGLIPFFIFSSISNRSVGAIEANQGLFNYRPV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
KPIDTIIARALLETLIYVAVYILLMLIVWMAGEYFEITNFLQLVLTWSLLIILSCGVGLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMVVGKTFPEMQKVLPILLKPLYFISCIMFPLHSIPKQYWSYLLWNPLVHVVELSREAVM
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGYISEGVSLNYLAMFTLVTLFIGLALYLTREEAMLTS
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAVKPRAVAYLKRLGSHHQMARSGFEVQKVTVEALFLREIRTRFGKFRLGYLWAILEPS
CCCCCHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
AHLLILLGIFGYIMHRTMPDISFPVFLLNGLIPFFIFSSISNRSVGAIEANQGLFNYRPV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
KPIDTIIARALLETLIYVAVYILLMLIVWMAGEYFEITNFLQLVLTWSLLIILSCGVGLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMVVGKTFPEMQKVLPILLKPLYFISCIMFPLHSIPKQYWSYLLWNPLVHVVELSREAVM
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGYISEGVSLNYLAMFTLVTLFIGLALYLTREEAMLTS
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1856162; 7715449 [H]