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The map label for this gene is kpsT [H]

Identifier: 218691244

GI number: 218691244

Start: 3524137

End: 3524805

Strand: Reverse

Name: kpsT [H]

Synonym: ECED1_3601

Alternate gene names: 218691244

Gene position: 3524805-3524137 (Counterclockwise)

Preceding gene: 218691245

Following gene: 218691243

Centisome position: 67.66

GC content: 40.21

Gene sequence:

>669_bases
ATGATTAAGATTGAAAATTTGACGAAGTCATATCGCACGCCAGCGGGTCGACATTATGTCTTTAAGGATTTAAATATTGA
AATCCCTTCAGGAAAAAGTGTTGCCTTTATTGGTCGCAACGGAGCGGGTAAATCAACGTTACTGAGAATGATTGGCGGCA
TTGACCGCCCCGACAGTGGAAAGATCATCACTAATAAAACAATATCATGGCCAGTCGGCCTCGCAGGTGGATTTCAGGGA
AGTTTAACCGGACGCGAAAACGTAAAATTTGTTGCGCGGTTATACGCGAAGCAAGAAGAGCTGAAAGAGAAAATTGAGTT
TGTCGAAGAATTTGCCGAACTCGGTAAGTACTTCGATATGCCGATTAAAACTTACTCATCTGGTATGCGATCGCGTTTAG
GCTTTGGTTTAAGCATGGCATTTAAGTTTGATTATTATATCGTCGATGAAGTAACTGCAGTCGGTGATGCCAGGTTTAAA
GAAAAATGCGCTCAATTGTTTAAAGAAAGGCATAAAGAATCTAGTTTTTTAATGGTTTCACATAGTTTGAATTCATTGAA
AGAGTTTTGTGATGTGGCGATTGTGTTTAAGGATGACAATGCGGTTAGTTTTCATGAGGATGTTCAGGAGGGGGTAGATG
AGTATCGGAATTTATTGCTCACAAGTTAG

Upstream 100 bases:

>100_bases
GCGAAGGCGTTAGTCTGAACTACCTTGCAATGTTCACTCTGGTCACCCTGTTCATCGGTCTGGCTTTATACCTAACGCGT
GAAGAGGCAATGCTGACATC

Downstream 100 bases:

>100_bases
ATATCTGGATTCTACGTGACATTATTTAACAATAACTAAATTTTGATAGTTTATATAATTAGAATATATCAAAAAGTAAA
TTGTTTATTGTATCGATAAA

Product: Polysialic acid transport ATP-binding protein kpsT

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIKIENLTKSYRTPAGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQG
SLTGRENVKFVARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFK
EKCAQLFKERHKESSFLMVSHSLNSLKEFCDVAIVFKDDNAVSFHEDVQEGVDEYRNLLLTS

Sequences:

>Translated_222_residues
MIKIENLTKSYRTPAGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQG
SLTGRENVKFVARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFK
EKCAQLFKERHKESSFLMVSHSLNSLKEFCDVAIVFKDDNAVSFHEDVQEGVDEYRNLLLTS
>Mature_222_residues
MIKIENLTKSYRTPAGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQG
SLTGRENVKFVARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFK
EKCAQLFKERHKESSFLMVSHSLNSLKEFCDVAIVFKDDNAVSFHEDVQEGVDEYRNLLLTS

Specific function: Putative ATP-binding protein, and an energy coupling component for the transport of polysialic acid across the cytoplasmic membrane [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI30795238, Length=204, Percent_Identity=25, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI27881501, Length=204, Percent_Identity=25.4901960784314, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI27477115, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI27436953, Length=211, Percent_Identity=24.1706161137441, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI45446740, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI47078218, Length=204, Percent_Identity=25.9803921568627, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1790467, Length=208, Percent_Identity=28.3653846153846, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788761, Length=218, Percent_Identity=27.0642201834862, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081709, Length=210, Percent_Identity=23.3333333333333, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1786803, Length=221, Percent_Identity=25.7918552036199, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI2367384, Length=68, Percent_Identity=47.0588235294118, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=197, Percent_Identity=25.3807106598985, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=197, Percent_Identity=25.3807106598985, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=197, Percent_Identity=25.3807106598985, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007184, Length=207, Percent_Identity=25.1207729468599, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221500365, Length=207, Percent_Identity=25.1207729468599, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25054; Mature: 25054

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIENLTKSYRTPAGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSG
CEEECCHHHHHCCCCCCEEEEEECEEECCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCC
KIITNKTISWPVGLAGGFQGSLTGRENVKFVARLYAKQEELKEKIEFVEEFAELGKYFDM
CEEECCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS
CHHHHHHHHHHHHCCCEEEEEEEEEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEH
HSLNSLKEFCDVAIVFKDDNAVSFHEDVQEGVDEYRNLLLTS
HHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKIENLTKSYRTPAGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSG
CEEECCHHHHHCCCCCCEEEEEECEEECCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCC
KIITNKTISWPVGLAGGFQGSLTGRENVKFVARLYAKQEELKEKIEFVEEFAELGKYFDM
CEEECCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS
CHHHHHHHHHHHHCCCEEEEEEEEEEEEEHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEH
HSLNSLKEFCDVAIVFKDDNAVSFHEDVQEGVDEYRNLLLTS
HHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2082146 [H]