BacMap

Definition	Escherichia coli ED1a chromosome, complete genome.
Accession	NC_011745
Length	5,209,548

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The map label for this gene is lolD [C]

Identifier: 218691051

GI number: 218691051

Start: 3336406

End: 3337116

Strand: Direct

Name: lolD [C]

Synonym: ECED1_3388

Alternate gene names: 218691051

Gene position: 3336406-3337116 (Clockwise)

Preceding gene: 218691050

Following gene: 218691057

Centisome position: 64.04

GC content: 52.74

Gene sequence:

>711_bases
GTGGCAATTGCAAAACGGAGCGCTCCAGCCACTATGTTAACGTTAAATCAGATATCTTATCGCTGGCCTGGCGCGGCAAC
GGATTGTCTTTGCGACATTTCTCTGCAACTCAAACAAGGTGAATGGCTGGCGCTGACCGGCGACAATGGCGCGGGAAAAT
CGACGCTGTTACGAGTAATGGCAGGTCTTCTTACGCCCACAGCCGGTACGGTTATGCTGCAACAACAAGCGATGAAAAAC
CTGAAAAACCGCCAGCGCGCGGCAAAGATTGGCGTACTGTTTCAGGAAGCGGAAAATCAGCTTTTTCACAGCACCGTTGC
TGACGAAATCGCATTTGGTTTGATACTGCAAAAATGCCCGGCGGATGAAATCACTCAACGTACCAATGCTGCCCTGCAAT
GCTGTCAGTTAGCAGACACTGCCAGCGCGCATCCGTTAGATCTGCATAGTGCGCAGCGACGGATGGTCGCCGTCGCCTGC
CTGGAAGCACTCTCTCCGCCACTATTGCTACTGGACGAGCCGAGTCGGGATTTTGACGAAAATTGGTTGAGCGTGTTTGA
AAGCTGGCTGGAAAAGTGCCGCCAGCGAGGCACGAGCGTCGTAGCAATCAGTCATGACGCCGCATTTACCCGGCGTCATT
TCTCTCGTGTGGTGCGACTGGAAGATGGTGTAATCAGGAACGTTAATCCATCAGACGATATTCACCCGTAG

Upstream 100 bases:

>100_bases
TGCTGTTGCAGCGCTTACAACACTGGGCGCTTGAACGTGGTTCGCTGATTATTCTTTTTGAACGTCATCACACACCTTTC
CTGAACCACTGCCAGCAAGC

Downstream 100 bases:

>100_bases
CGGTCATCATTAAGGTCAAATTTGCAGGCAGACTCTCTTCCAGCACCCGGCGAACATTCGGCCCGTCGGTACGGTCATAA
AAGGCTTCTGCGTCTGCCAG

Product: putative ATP-binding protein of ABC transport system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MAIAKRSAPATMLTLNQISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTVMLQQQAMKN
LKNRQRAAKIGVLFQEAENQLFHSTVADEIAFGLILQKCPADEITQRTNAALQCCQLADTASAHPLDLHSAQRRMVAVAC
LEALSPPLLLLDEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPSDDIHP

Sequences:

>Translated_236_residues
MAIAKRSAPATMLTLNQISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTVMLQQQAMKN
LKNRQRAAKIGVLFQEAENQLFHSTVADEIAFGLILQKCPADEITQRTNAALQCCQLADTASAHPLDLHSAQRRMVAVAC
LEALSPPLLLLDEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPSDDIHP
>Mature_235_residues
AIAKRSAPATMLTLNQISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTVMLQQQAMKNL
KNRQRAAKIGVLFQEAENQLFHSTVADEIAFGLILQKCPADEITQRTNAALQCCQLADTASAHPLDLHSAQRRMVAVACL
EALSPPLLLLDEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPSDDIHP

Specific function: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system [H]

COG id: COG1118

COG function: function code P; ABC-type sulfate/molybdate transport systems, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI4505771, Length=232, Percent_Identity=28.0172413793103, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI9961252, Length=232, Percent_Identity=28.0172413793103, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI9961250, Length=239, Percent_Identity=27.1966527196653, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI42741659, Length=230, Percent_Identity=27.3913043478261, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI255708477, Length=220, Percent_Identity=26.3636363636364, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI9955963, Length=187, Percent_Identity=29.9465240641711, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI148612844, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87081834, Length=214, Percent_Identity=32.7102803738318, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789873, Length=215, Percent_Identity=30.6976744186047, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788761, Length=215, Percent_Identity=34.8837209302326, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787370, Length=202, Percent_Identity=34.1584158415842, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87081791, Length=236, Percent_Identity=33.0508474576271, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1790467, Length=200, Percent_Identity=30.5, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788225, Length=206, Percent_Identity=29.126213592233, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786398, Length=207, Percent_Identity=29.4685990338164, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789032, Length=208, Percent_Identity=29.3269230769231, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1787029, Length=224, Percent_Identity=27.2321428571429, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790739, Length=213, Percent_Identity=30.9859154929577, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI87082267, Length=225, Percent_Identity=25.7777777777778, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787089, Length=224, Percent_Identity=30.3571428571429, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI48995001, Length=204, Percent_Identity=30.3921568627451, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1790525, Length=202, Percent_Identity=28.7128712871287, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787712, Length=205, Percent_Identity=27.3170731707317, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786253, Length=199, Percent_Identity=31.6582914572864, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081709, Length=227, Percent_Identity=25.1101321585903, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787164, Length=217, Percent_Identity=30.4147465437788, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789672, Length=230, Percent_Identity=25.6521739130435, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789891, Length=229, Percent_Identity=28.3842794759825, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787759, Length=243, Percent_Identity=27.5720164609054, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786803, Length=201, Percent_Identity=28.3582089552239, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788897, Length=209, Percent_Identity=29.1866028708134, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788472, Length=221, Percent_Identity=23.9819004524887, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786563, Length=192, Percent_Identity=31.7708333333333, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=26.457399103139, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=29.6650717703349, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787792, Length=202, Percent_Identity=30.1980198019802, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790190, Length=206, Percent_Identity=26.6990291262136, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786872, Length=228, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789864, Length=232, Percent_Identity=26.2931034482759, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786703, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786345, Length=222, Percent_Identity=28.3783783783784, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788506, Length=211, Percent_Identity=28.9099526066351, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786698, Length=216, Percent_Identity=26.3888888888889, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787500, Length=211, Percent_Identity=26.5402843601896, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787547, Length=214, Percent_Identity=22.8971962616822, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=197, Percent_Identity=26.3959390862944, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081782, Length=195, Percent_Identity=31.2820512820513, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788450, Length=223, Percent_Identity=25.5605381165919, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789593, Length=180, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788053, Length=204, Percent_Identity=29.9019607843137, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082268, Length=214, Percent_Identity=22.8971962616822, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1787112, Length=227, Percent_Identity=27.3127753303965, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=231, Percent_Identity=26.8398268398268, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17558664, Length=234, Percent_Identity=24.3589743589744, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17569143, Length=228, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=230, Percent_Identity=24.3478260869565, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=235, Percent_Identity=22.9787234042553, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=210, Percent_Identity=25.2380952380952, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=161, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=228, Percent_Identity=23.2456140350877, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=217, Percent_Identity=23.0414746543779, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=201, Percent_Identity=26.3681592039801, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573571, Length=176, Percent_Identity=28.4090909090909, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28573573, Length=176, Percent_Identity=28.4090909090909, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR022216
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran; PF12558 DUF3744 [H]

EC number: NA

Molecular weight: Translated: 25990; Mature: 25859

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIAKRSAPATMLTLNQISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVM
CCCCCCCCCCCEEEEHHHCCCCCCCCCHHEEECEEEEECCCEEEEECCCCCCHHHHHHHH
AGLLTPTAGTVMLQQQAMKNLKNRQRAAKIGVLFQEAENQLFHSTVADEIAFGLILQKCP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADEITQRTNAALQCCQLADTASAHPLDLHSAQRRMVAVACLEALSPPLLLLDEPSRDFDE
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
NWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPSDDIHP
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCEECCCCCCCCCCC
>Mature Secondary Structure 
AIAKRSAPATMLTLNQISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVM
CCCCCCCCCCEEEEHHHCCCCCCCCCHHEEECEEEEECCCEEEEECCCCCCHHHHHHHH
AGLLTPTAGTVMLQQQAMKNLKNRQRAAKIGVLFQEAENQLFHSTVADEIAFGLILQKCP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADEITQRTNAALQCCQLADTASAHPLDLHSAQRRMVAVACLEALSPPLLLLDEPSRDFDE
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
NWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGVIRNVNPSDDIHP
HHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA