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The map label for this gene is hflC [H]

Identifier: 218691057

GI number: 218691057

Start: 3342109

End: 3343077

Strand: Direct

Name: hflC [H]

Synonym: ECED1_3396

Alternate gene names: 218691057

Gene position: 3342109-3343077 (Clockwise)

Preceding gene: 218691051

Following gene: 218691059

Centisome position: 64.15

GC content: 48.71

Gene sequence:

>969_bases
TTGTCTGTTTTCTCATCACCTCATGTGACATATTCCCCACTTTACTCAAGGAAGATTCATATGAAAGCACCTGTTTCATT
AACCTCATTTCGCCCACAAAAATCTCTTGCTATCGCCATTGGCGTGCTTGCCGTGGTTGTGCTGCCATTTCTCTCGTATT
ACACCGTTAATGAAGGTGAACGCGGCATTTTGCTGCGCTACGGAAAAATCGTAAAAGTTGCCGAGCCGGGGCTGGGTTTT
AAGATCCCTTTTATGGAAAGCGTAGAGAAAATTTCCACGCGTAATCAGGCTGTGGTCTATCAGGGATTACAGGCCTACAG
CCGCGACCAGCAACCGGCACAAATGACAGTATCAGTCAGCTTCCACATTAAACCTTCAGAAGCAGGCGCGGTTTATACCA
CCTACAACACCATTGAAGCATTAAAAGATCGTCTGATTGTCCGTCAGTTGCCAACTCAACTGGAGAACGTTTTCGGACAA
TATACCGCCATCAGCGCCGTACAGGATCGTACAAAACTGGTTCAGGATCTGCAAAATGCCATGCGCAAAGCCGTTGTTGG
GCCAGTGGTAATTGACGGGGTCCAGATTGAAAATATTGATTTTTCTGACGCTTATGAAAAGTCGATTGAAGACCGAATGA
AAGCAGAAGTCGCCATTGCCACGCGTAAGCAAAATCTGGAAACGGAGAAAATCCAGGCGCAAATAGCGGTAACTCAGGCC
CAGGCGGAAGCAGACAGTAAACTAGCGGCAGCCAAAGCAGAAGCGGAAACTATTCGCGTAAGAGGCGCGGCAGAGGCTGA
AACTATTCGTTTAAAAAGTGCGGCTGAAGCAGAAGCTATCCGCCTGCGCGGTGAAGCTCTGCGGGAGAATCCCGGACTTG
TTGCCCTCACCACTGCTGAGCGTTGGGACGGTAAACTGCCCGATACCATGATCCCCGGCAGCACAGTTCCGTTTATCTCT
ACTAAGTAA

Upstream 100 bases:

>100_bases
TGATACACATCTCTATTTTCTTATTGAATGTTCGAAAACATACTTATTACGTTTATTATTTTTTCGCTCATCCCCTTTAT
AAATTCTGAATTATCGGCTG

Downstream 100 bases:

>100_bases
AAAAGGGCCGCTTTCGCGGCCCTTGAGACTGATAGCAAAGACAAAACTGCCTGATGCGCTACGCTTATCAGGCCTACATA
CTTCCTGCAATATGTTGAAT

Product: putative membrane protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSVFSSPHVTYSPLYSRKIHMKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGF
KIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENVFGQ
YTAISAVQDRTKLVQDLQNAMRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRKQNLETEKIQAQIAVTQA
QAEADSKLAAAKAEAETIRVRGAAEAETIRLKSAAEAEAIRLRGEALRENPGLVALTTAERWDGKLPDTMIPGSTVPFIS
TK

Sequences:

>Translated_322_residues
MSVFSSPHVTYSPLYSRKIHMKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGF
KIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENVFGQ
YTAISAVQDRTKLVQDLQNAMRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRKQNLETEKIQAQIAVTQA
QAEADSKLAAAKAEAETIRVRGAAEAETIRLKSAAEAEAIRLRGEALRENPGLVALTTAERWDGKLPDTMIPGSTVPFIS
TK
>Mature_321_residues
SVFSSPHVTYSPLYSRKIHMKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGILLRYGKIVKVAEPGLGFK
IPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFHIKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENVFGQY
TAISAVQDRTKLVQDLQNAMRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRKQNLETEKIQAQIAVTQAQ
AEADSKLAAAKAEAETIRVRGAAEAETIRLKSAAEAEAIRLRGEALRENPGLVALTTAERWDGKLPDTMIPGSTVPFIST
K

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=301, Percent_Identity=24.2524916943522, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 35370; Mature: 35239

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFSSPHVTYSPLYSRKIHMKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGE
CCCCCCCCCEECCHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCC
RGILLRYGKIVKVAEPGLGFKIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVS
CEEEEEECCEEEEECCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEE
FHIKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDLQNA
EEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRKQNLETEKIQAQIAVTQA
HHHHHCCCEEECCEEEECCCCHHHHHHHHHHHHHHHEEEEHHHCCCCHHHHHEEEEEEHH
QAEADSKLAAAKAEAETIRVRGAAEAETIRLKSAAEAEAIRLRGEALRENPGLVALTTAE
HHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCHHHHHHHCCHHHHCCCCEEEEEECH
RWDGKLPDTMIPGSTVPFISTK
HCCCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
SVFSSPHVTYSPLYSRKIHMKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGE
CCCCCCCCEECCHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCC
RGILLRYGKIVKVAEPGLGFKIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVS
CEEEEEECCEEEEECCCCCEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEE
FHIKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDLQNA
EEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRKQNLETEKIQAQIAVTQA
HHHHHCCCEEECCEEEECCCCHHHHHHHHHHHHHHHEEEEHHHCCCCHHHHHEEEEEEHH
QAEADSKLAAAKAEAETIRVRGAAEAETIRLKSAAEAEAIRLRGEALRENPGLVALTTAE
HHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCHHHHHHHCCHHHHCCCCEEEEEECH
RWDGKLPDTMIPGSTVPFISTK
HCCCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]