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The map label for this gene is virB11 [H]

Identifier: 218689997

GI number: 218689997

Start: 2207832

End: 2208857

Strand: Direct

Name: virB11 [H]

Synonym: ECED1_2270

Alternate gene names: 218689997

Gene position: 2207832-2208857 (Clockwise)

Preceding gene: 218689996

Following gene: 218689998

Centisome position: 42.38

GC content: 47.27

Gene sequence:

>1026_bases
ATGACCGCTAAGAATATTTCCCTCGACCGCTATAAACAGCGTTTCTTTGGCGACTTTCTAGAGCTTCCCGGCCTGACGGA
GATCGCCGTCAATCGTCCAGGTGAGCTGTATACCAAAATCAACGGCGTATGGGAGCAGCACGCCGTTCCTTTGTCCTATG
AGGATTGCTACAACTTTGCCCGGTGCCTGGCAAAGCACCACGGCGACAATATCGAAGATATTAAGCCGGGGCTGTCAGCC
ACGCTGGAATCTGGCGAACGGTGCCAGGTGATTGTTCCCCCGGCCTGTGAGCGCGATACGGTGTCTATCACCATCCGTAA
GCCATCGAAGGTACAAATCCCGCATCAGTCATACATCGATGCGGGATTTTATAACCGGGTAACAGGCGAGGAAAAAACGG
AGACGCACGACGAGGAATTAATTGCATTGTACAATACAAAAAATATTCCTCTGTTTATGGAGAAATGCGTCGAGTACGGT
AAAACTCTCGCGGTCGCCGGGGAAACAAGCACCGGGAAAACCACCTATATGAAAATGTTGATAGGGTATATTCCTGTACA
TCTTCGGATATCAACCATTGAGGACAACCCGGAAATCACGTTCTTTATCCATAAAAACTACGTCCATCTTTTTTATCCGT
CAGAATCATCAGATGAAAAAGGTTCTATCGTTACCCCGGCGAGCCTTTTACGCTGGAATTACCGTATGAACCCTGACCGC
ATTTTATTAACAGAGGTTCGCGGTGCGGAAGCCTGGGACTTCCTTAAAATAACAGGTTCCGGCCATGAAGGGAGTATGAC
CTCCATTCATGCAGGATCAGCGAAAGAAGCTATAGATGGGTTTATTACCCGTTGCTATGAAAATCCACAGTGCGCCCAGC
TCCCCTATACATTTATGTTACGTAAGGTTCTGGATAGCCTGGACGTGATTGTGAGCATTGATTTAGACGGAAATGTTCGC
CGTATGAATGACATCTATTTCCGTCCAATTCATCGAAACCAGTATTTTGAGGAAATGAAAGCATGA

Upstream 100 bases:

>100_bases
AATATTCCCCCAACGCTCTATAAGAATCAGGGCGAGATCATCAACCTAATCACAGGCGAGGATATTGATTTTTCCAACAT
CTATACACTGAGGTTGAAAA

Downstream 100 bases:

>100_bases
TAAAGAAACTTAAAGTCATCATGTTGGCAGCAATAGTTACCGGATGTTCATCGCCGCCGCCTCCCGTTCCTGTGGAGTGG
GATAAAGCCGCTGCCCCATT

Product: putative type IV secretory pathway VirB11 component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELYTKINGVWEQHAVPLSYEDCYNFARCLAKHHGDNIEDIKPGLSA
TLESGERCQVIVPPACERDTVSITIRKPSKVQIPHQSYIDAGFYNRVTGEEKTETHDEELIALYNTKNIPLFMEKCVEYG
KTLAVAGETSTGKTTYMKMLIGYIPVHLRISTIEDNPEITFFIHKNYVHLFYPSESSDEKGSIVTPASLLRWNYRMNPDR
ILLTEVRGAEAWDFLKITGSGHEGSMTSIHAGSAKEAIDGFITRCYENPQCAQLPYTFMLRKVLDSLDVIVSIDLDGNVR
RMNDIYFRPIHRNQYFEEMKA

Sequences:

>Translated_341_residues
MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELYTKINGVWEQHAVPLSYEDCYNFARCLAKHHGDNIEDIKPGLSA
TLESGERCQVIVPPACERDTVSITIRKPSKVQIPHQSYIDAGFYNRVTGEEKTETHDEELIALYNTKNIPLFMEKCVEYG
KTLAVAGETSTGKTTYMKMLIGYIPVHLRISTIEDNPEITFFIHKNYVHLFYPSESSDEKGSIVTPASLLRWNYRMNPDR
ILLTEVRGAEAWDFLKITGSGHEGSMTSIHAGSAKEAIDGFITRCYENPQCAQLPYTFMLRKVLDSLDVIVSIDLDGNVR
RMNDIYFRPIHRNQYFEEMKA
>Mature_340_residues
TAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELYTKINGVWEQHAVPLSYEDCYNFARCLAKHHGDNIEDIKPGLSAT
LESGERCQVIVPPACERDTVSITIRKPSKVQIPHQSYIDAGFYNRVTGEEKTETHDEELIALYNTKNIPLFMEKCVEYGK
TLAVAGETSTGKTTYMKMLIGYIPVHLRISTIEDNPEITFFIHKNYVHLFYPSESSDEKGSIVTPASLLRWNYRMNPDRI
LLTEVRGAEAWDFLKITGSGHEGSMTSIHAGSAKEAIDGFITRCYENPQCAQLPYTFMLRKVLDSLDVIVSIDLDGNVRR
MNDIYFRPIHRNQYFEEMKA

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb11 is essential for pathogenesis in mice but is not required for intracellular survival [H]

COG id: COG0630

COG function: function code NU; Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014155
- InterPro:   IPR002078
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 38925; Mature: 38794

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELYTKINGVWEQHAVPLSYEDCYNFA
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCHHHHCCCCCCHHHHHHHH
RCLAKHHGDNIEDIKPGLSATLESGERCQVIVPPACERDTVSITIRKPSKVQIPHQSYID
HHHHHHCCCCHHHHCCCHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCEEECCCHHHHC
AGFYNRVTGEEKTETHDEELIALYNTKNIPLFMEKCVEYGKTLAVAGETSTGKTTYMKML
CCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHH
IGYIPVHLRISTIEDNPEITFFIHKNYVHLFYPSESSDEKGSIVTPASLLRWNYRMNPDR
HHHEEEEEEEEEECCCCCEEEEEEECEEEEECCCCCCCCCCCEECCHHHHEECCCCCCCE
ILLTEVRGAEAWDFLKITGSGHEGSMTSIHAGSAKEAIDGFITRCYENPQCAQLPYTFML
EEEEECCCCCCEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
RKVLDSLDVIVSIDLDGNVRRMNDIYFRPIHRNQYFEEMKA
HHHHCCCEEEEEEECCCCCEEECCEEEEECHHHHHHHHHCC
>Mature Secondary Structure 
TAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELYTKINGVWEQHAVPLSYEDCYNFA
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCHHHHCCCCCCHHHHHHHH
RCLAKHHGDNIEDIKPGLSATLESGERCQVIVPPACERDTVSITIRKPSKVQIPHQSYID
HHHHHHCCCCHHHHCCCHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCEEECCCHHHHC
AGFYNRVTGEEKTETHDEELIALYNTKNIPLFMEKCVEYGKTLAVAGETSTGKTTYMKML
CCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCEEEEECCCCCCHHHHHHHH
IGYIPVHLRISTIEDNPEITFFIHKNYVHLFYPSESSDEKGSIVTPASLLRWNYRMNPDR
HHHEEEEEEEEEECCCCCEEEEEEECEEEEECCCCCCCCCCCEECCHHHHEECCCCCCCE
ILLTEVRGAEAWDFLKITGSGHEGSMTSIHAGSAKEAIDGFITRCYENPQCAQLPYTFML
EEEEECCCCCCEEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
RKVLDSLDVIVSIDLDGNVRRMNDIYFRPIHRNQYFEEMKA
HHHHCCCEEEEEEECCCCCEEECCEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]