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The map label for this gene is irp [H]

Identifier: 218689972

GI number: 218689972

Start: 2167106

End: 2168509

Strand: Reverse

Name: irp [H]

Synonym: ECED1_2245

Alternate gene names: 218689972

Gene position: 2168509-2167106 (Counterclockwise)

Preceding gene: 218689973

Following gene: 218689971

Centisome position: 41.63

GC content: 58.9

Gene sequence:

>1404_bases
TTGAGCAGGGTACTCATGCACAATTGCTCTCACATCATGGACGTTATCAGGCGCTGTGGCAGGCGCAAATGGCCGCGCGC
GTGTGGCGCGACGACGGGGTTTCCGCGTCTGGAGAGTGGGTGCATGAGTGATGTTCAGTCGAATGTGAAACCGCTGACGT
TGACGACCGGGCGGGTGATTTTTGCTATTGCCGGCGTCTATGTGACGCAGAGTCTGGTATCGGCGCTGTCTATGCAGTCC
TTACCCGCGCTGGTGCGCGCTGCTGGCGGATCGCTGGCGCTTGCCGGTGCGACAACCCTGTTCATGCTGCCCTGGGCGCT
GAAGTTTATTTGGGCGCCGTGGATCGAACGCTGGCGGCTTCCGCCCGGTAGCCAGGAACGCCGTTCGCGGATGTTAATCC
TGCGTGGTCAGGTCGCGCTAGCGGCGATCCTGATGATTGCCGCAGCGATTGGCTGGTTTGGGCGAGAAGGAGGATTTCCC
GATACGCAAATCGTCGCGTTATTTGTTCTGTTTATGGTGGCAGGCACGGTCGCTTCCACCATTGATATCGCCAGCGACGG
CTTTTGCGTCGATCAACTGACTCGCGCGGGTTACGGCTGGGGAAACAGCGTGCAGGTCGGCGGCAGCTATCTGGGAATGA
TGTGCGGCGGCGGGGTGTTCCTAATGTTGTCGGCAGCATCCGGCTGGCCTGTCGCCATGCTGATGATGGCGATGCTGATT
ATGGCGCTGTCATTCCCGCTGTGGCGCATTACGGAGCCGACGCGAACAGCGCCTATCCCGCATGTTCCGGCGTTAGGTTA
TGCGCTAAGGAGGAAGCAGGCGCGCCTGGGCTTACTGCTGGTATTAATGCTGAATTCAGGTATGCGGTTTGTGCTGCCTC
TTCTGGCGCCGCTGTTGTTGGATCATGGGTTGAGCATGTCTGCGTTGGGCGCGCTGTTCAGCGGCGGCAATATTGCAGCG
GGCATAGCAGGAACGCTGGCCGGCGGATTACTGATGAAATACACCTCACCCGGCAGAGCGCTGTTGACGGCTTATGGCGT
CCAGGGGATCGCGCTGCTGGCGGTGGTGATGACGTTCATGATGGCGCCGGGTCATCTGTTGCTGCCGATTCTCCAGTGTC
TGGTCATTGTCCAGTCCATTTCGCTGGCCTGCGCGCTGGTCTGTCTTTACGCCACGCTGATGTCGCTTTCATCGCCTTTG
CAGGCCGGTGTCGACTTCACCCTCTTTCAATGTACTGACGCGGCAATCGCCATCCTGGCTGGTGTTATCGGCGGCGTTGT
TGCTCAACATTTTGGCTATGCGGCCTGCTTCCTGTTTGCCGGGGTATTCACGTTGCTGGCGGCGTGGGTTGCTTATATCC
GGCTGCATTCGGCAAGAGAACTGATGACAAGCGCAATTGATTGA

Upstream 100 bases:

>100_bases
GATAACCTGGTTCACAACCGGACGGTGATTATCATCGCTCACCGTTTATCCACCATCGCCGGGGCCGGAAACATTCTGGT
GATGGAAGAGGGACAGGTGG

Downstream 100 bases:

>100_bases
TCCGGGAATAACACAGAGAGGTAAGGGATGAAAATCAGTGAATTTTTACACCTGGCGTTACCAGAGGAACAATGGCTGCC
GACGATTTCTGGCGTTTTAC

Product: yersiniabactin-iron transporter permease YbtX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSRVLMHNCSHIMDVIRRCGRRKWPRACGATTGFPRLESGCMSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQS
LPALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAILMIAAAIGWFGREGGFP
DTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRAGYGWGNSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAMLI
MALSFPLWRITEPTRTAPIPHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAA
GIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTFMMAPGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPL
QAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAGVFTLLAAWVAYIRLHSARELMTSAID

Sequences:

>Translated_467_residues
MSRVLMHNCSHIMDVIRRCGRRKWPRACGATTGFPRLESGCMSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQS
LPALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAILMIAAAIGWFGREGGFP
DTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRAGYGWGNSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAMLI
MALSFPLWRITEPTRTAPIPHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAA
GIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTFMMAPGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPL
QAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAGVFTLLAAWVAYIRLHSARELMTSAID
>Mature_466_residues
SRVLMHNCSHIMDVIRRCGRRKWPRACGATTGFPRLESGCMSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSL
PALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAILMIAAAIGWFGREGGFPD
TQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRAGYGWGNSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAMLIM
ALSFPLWRITEPTRTAPIPHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAAG
IAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTFMMAPGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPLQ
AGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAGVFTLLAAWVAYIRLHSARELMTSAID

Specific function: Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786636, Length=380, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49576; Mature: 49445

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVLMHNCSHIMDVIRRCGRRKWPRACGATTGFPRLESGCMSDVQSNVKPLTLTTGRVI
CCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHH
FAIAGVYVTQSLVSALSMQSLPALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
PPGSQERRSRMLILRGQVALAAILMIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVAST
CCCCHHHHCCEEHEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IDIASDGFCVDQLTRAGYGWGNSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAMLI
HHHCCCCCHHHHHHHCCCCCCCCEEECHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
MALSFPLWRITEPTRTAPIPHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLL
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DHGLSMSALGALFSGGNIAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTFM
HCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHH
MAPGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEHHHHHHHHHHH
GVIGGVVAQHFGYAACFLFAGVFTLLAAWVAYIRLHSARELMTSAID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRVLMHNCSHIMDVIRRCGRRKWPRACGATTGFPRLESGCMSDVQSNVKPLTLTTGRVI
CCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCHHH
FAIAGVYVTQSLVSALSMQSLPALVRAAGGSLALAGATTLFMLPWALKFIWAPWIERWRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
PPGSQERRSRMLILRGQVALAAILMIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVAST
CCCCHHHHCCEEHEEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IDIASDGFCVDQLTRAGYGWGNSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAMLI
HHHCCCCCHHHHHHHCCCCCCCCEEECHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
MALSFPLWRITEPTRTAPIPHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLL
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DHGLSMSALGALFSGGNIAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTFM
HCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHH
MAPGHLLLPILQCLVIVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEEHHHHHHHHHHH
GVIGGVVAQHFGYAACFLFAGVFTLLAAWVAYIRLHSARELMTSAID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]