Click here to switch to the map view.

The map label for this gene is sucC [H]

Identifier: 218551370

GI number: 218551370

Start: 4252874

End: 4254043

Strand: Direct

Name: sucC [H]

Synonym: EFER_4151

Alternate gene names: 218551370

Gene position: 4252874-4254043 (Clockwise)

Preceding gene: 218551369

Following gene: 218551371

Centisome position: 92.68

GC content: 51.88

Gene sequence:

>1170_bases
ATGAATTTACATGAGTATCAGGCCAAATCGTTACTGGCTGGCATGGGGATGCCGTGTCCAAAAGAGATAGCTATCCAACA
GATTTCGCAACTGGCAGATGCCTGGCAACATATTGCTTGCCCGAGTAAAGGCGCGGTACTTAAAGCGCAGGTACACGCTG
GTGGGCGCGGTAAAGCTGGCGGCGTAAAAGTGCTTAAGCAGCTGCCGGAAGCACAGGCTTTTGTACAGCAAATGCTGGGA
TCGCAACTGGTGACTTATCAGACCGGGCCAGAAGGGCAGTATGTCAGCAGTATTTTGCTGTGCGAAAACATTTATCCGGT
ACGCCAGGAACTCTATTTTGGCATGGTGGTGGATCGTGAAAGCCAGCGGGTCACGTTTATTGTCAGCCCGGAAGGTGGTG
TGGAAATTGAAAAAGTCGCCCATGAGACACCGGAGAAAATCAGCAGTGTCAGCATTGATCCACTGACAGGCGTGCAGCCT
TGCCATATCCGCGAAATGTTTGCTGTTCTGCAACTGGAACACGGGCTATTTGCTGCCTTTAGTCGCCTGGTTAATCAGGC
GTGGAAAGCCTTTAACGAACTGGATTTTGCCCTGCTGGAAATTAACCCTCTGGTGTTGCGGGAAACGGGCGAATTTATGT
GTGCAGATGCGAAAGTATCGTTGGATGATAACGCGCTGTATCGCCACCCGGAACTCCAGGCGCTACGCGATGAAACCCAG
GAAGATCCGCGCGAAAGCCAGGCGGCGAAGCTTGATCTTAACTATGTCTCGCTGGACGGAAACATCGGCTGCATGGTCAA
TGGTGCCGGATTGGCTATGGCAACCATGGACATCATCAAACTGTACGGTGAACAACCAGCAAACTTCCTGGATGTTGGCG
GTGGCGCAACTCAGGAGCGCGTCAGTGAAGCCTTTCGTCTGATTGTTTCCGACAGCAAAGTGAAAGCCATTCTGGTCAAT
ATTTTTGGTGGGATTGTTCGTTGCGATATGATCGCCCGAGCCATTATTCATGCACTGAATGAGGCCAGCATCACCCTGCC
TGTCGTGGTGCGTCTCTCCGGTAATAACGCCGTCGAAGGGCAGCGGTTACTGGCAGAAAGTGGCCTGACGGTGGAAGCCG
TCGATTCTCTGGATGATGCCGCGAAACGCATCATTGCGTTACTGAATTAA

Upstream 100 bases:

>100_bases
GGTACATGCGCATCCGACGTTAAGCGAAGTCATCCACGAAGCAGCAATGGCCTTGAATAATAAAGTATTACACGGATAAC
ACACACCACTGAGGGAATAT

Downstream 100 bases:

>100_bases
CAGGAGGTTAAGATGAGCGTTTTGATCAACAAACACACGCGGGTACTGGTGCAGGGCATTACTGGCAAAAACGGCACATT
TCATACAGAGCAGGCTATTG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAGGVKVLKQLPEAQAFVQQMLG
SQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRESQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQP
CHIREMFAVLQLEHGLFAAFSRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQALRDETQ
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQERVSEAFRLIVSDSKVKAILVN
IFGGIVRCDMIARAIIHALNEASITLPVVVRLSGNNAVEGQRLLAESGLTVEAVDSLDDAAKRIIALLN

Sequences:

>Translated_389_residues
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAGGVKVLKQLPEAQAFVQQMLG
SQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRESQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQP
CHIREMFAVLQLEHGLFAAFSRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQALRDETQ
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQERVSEAFRLIVSDSKVKAILVN
IFGGIVRCDMIARAIIHALNEASITLPVVVRLSGNNAVEGQRLLAESGLTVEAVDSLDDAAKRIIALLN
>Mature_389_residues
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAGGVKVLKQLPEAQAFVQQMLG
SQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRESQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQP
CHIREMFAVLQLEHGLFAAFSRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQALRDETQ
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQERVSEAFRLIVSDSKVKAILVN
IFGGIVRCDMIARAIIHALNEASITLPVVVRLSGNNAVEGQRLLAESGLTVEAVDSLDDAAKRIIALLN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=396, Percent_Identity=45.4545454545455, Blast_Score=328, Evalue=6e-90,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=39.3782383419689, Blast_Score=275, Evalue=5e-74,
Organism=Homo sapiens, GI294862256, Length=361, Percent_Identity=39.612188365651, Blast_Score=258, Evalue=5e-69,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=55.9585492227979, Blast_Score=407, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17539378, Length=397, Percent_Identity=38.7909319899244, Blast_Score=293, Evalue=7e-80,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=41.2658227848101, Blast_Score=289, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=39.2947103274559, Blast_Score=290, Evalue=3e-79,
Organism=Drosophila melanogaster, GI21356231, Length=403, Percent_Identity=41.6873449131514, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=44.3298969072165, Blast_Score=300, Evalue=8e-82,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=44.3298969072165, Blast_Score=300, Evalue=8e-82,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=44.4730077120823, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=44.4730077120823, Blast_Score=298, Evalue=4e-81,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42280; Mature: 42280

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCH
GVKVLKQLPEAQAFVQQMLGSQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRE
HHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHEEEECC
SQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQPCHIREMFAVLQLEHGLFAAF
CCEEEEEECCCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQALRDETQ
HHHHHHHHHHHHHCCEEEEECCCEEEECCCCEEEECCEEECCCCCEECCCHHHHHHHHHH
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQER
CCCCHHHHEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHH
VSEAFRLIVSDSKVKAILVNIFGGIVRCDMIARAIIHALNEASITLPVVVRLSGNNAVEG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCH
QRLLAESGLTVEAVDSLDDAAKRIIALLN
HHHHHHCCCEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCH
GVKVLKQLPEAQAFVQQMLGSQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRE
HHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHEEEECC
SQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQPCHIREMFAVLQLEHGLFAAF
CCEEEEEECCCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQALRDETQ
HHHHHHHHHHHHHCCEEEEECCCEEEECCCCEEEECCEEECCCCCEECCCHHHHHHHHHH
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQER
CCCCHHHHEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHH
VSEAFRLIVSDSKVKAILVNIFGGIVRCDMIARAIIHALNEASITLPVVVRLSGNNAVEG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCH
QRLLAESGLTVEAVDSLDDAAKRIIALLN
HHHHHHCCCEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA