Click here to switch to the map view.

The map label for this gene is licC [H]

Identifier: 218551192

GI number: 218551192

Start: 4058724

End: 4060055

Strand: Direct

Name: licC [H]

Synonym: EFER_3957

Alternate gene names: 218551192

Gene position: 4058724-4060055 (Clockwise)

Preceding gene: 218551191

Following gene: 218551193

Centisome position: 88.45

GC content: 50.08

Gene sequence:

>1332_bases
ATGAGTTCGTTATATCAATCAATGGTTGCCGTTATTGAACAATCCATCACACCGCTTGCCGGGAAGCTGGGGCAGCAAAA
ATATGTGATTGCCATCCGCGACGGTTTTACTGCCGCTCTACCGTTTATGATCATCGGTTCGTTTATGCTGGTGTTTATTT
TCCCACCGTTTTCGGCTGAAACAACCAACAGTTTTGCCCGAGGCTGGCTGGATTTTTCCGCCACCTACCGTGAACAGCTA
ATGTTGCCATTTAACCTCAGCATGGGAGTGATGACTTTCTTCATCTCAGTAGGGATCGGTGCCAGTCTTGGGCGACAGTT
TAATCTCGATCCGATTATGTCTGGCTTGCTGGCATTTATGGCATTTTTACTGGTCGCAGCGCCTTACGCTGACGGCAAAA
TATCGACTCAATATCTTTCCGGGCAAGGTATTTTCACTTCGCTGATTACCGCCATTTATGCCACTCGTGTGTACGCCTGG
TTAAAACAACACAACGTGACAATCCGCTTACCCAAAGAAGTCCCTACTGGGGTTGCGCGTTCCTTTGAGATCCTTATCCC
GGTTCTGGTGGTCATTGCTACGCTACACCCACTGAATCTGTTTATTGAAGCCCAGACTGGAATGATTATTCCTGAGGCGA
TCATGCATCTTTTAGCGCCACTGGTCTCTGCCTCTGATTCTCTGCCTGCAATTCTGCTGTCTGTTCTGATGTGTCAGATT
TTCTGGTTCGCAGGTATTCATGGTTCACTGATTGTAACAGGCATCATGAATCCCTTCTGGATGGCAAACCTGTCGGCAAA
TCAGGCAGCTCTTGCCGCTGGCGCAGCGCTTCCTCACGTTTATCTGCAAGGGTTTTGGGATCACTACCTGTTGATTGGCG
GTGTCGGCTCGACGTTACCGCTGGCGTTCTTGCTGTTACGCAGCCGCGTTGCTCACTTGCGTACCATCGGAAAAATGGGC
GTTGTCCCCAGTTTTTTCAACATCAATGAGCCTATTCTGTTCGGTGCGCCGATCATCATGAATCCGATGTTGTTTATCCC
GTTCGTTTTCGTGCCAATTATTAACGCCATCCTGGCCTATACCGCGACCAGACTAGGCTGGCTGGCGCAGGTTGTCTCAT
TAACGCCATGGACTACACCTGCTCCAATTGGCGCCTCCTGGGCTGCCAACTGGGCACTTAGCCCGGTAGTGATGTGCATT
ATCTGTATGGTGATGTCGGCGCTGATGTACCTCCCATTCTTGCGCGCCTATGAACGCTCTTTGCTGAAAAGCGAAGAACA
AAAAGCGCAGGATCCCGTCTCCGTGGCCAATGCAGCCCGTAGCAACTCATAA

Upstream 100 bases:

>100_bases
GAAAGCCATTGATATGGCGGACTACGGAATGCAACGGGGTGACAAGGTGCTGGATTACGCTCTGTCGCTTATTGCAGCGA
CACATTAGAAAGGTGTCATT

Downstream 100 bases:

>100_bases
TGAATCAAGGAGTAAGAACAATGAGATACCGTTTTCCCGACAACTTCTGGTGGGGTAGTGCTTGCTCTGCGCTGCAAACC
GAAGGGGATAGTCTGAACGG

Product: PTS subunit, cellobiose/chitosan-specific IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSSLYQSMVAVIEQSITPLAGKLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSAETTNSFARGWLDFSATYREQL
MLPFNLSMGVMTFFISVGIGASLGRQFNLDPIMSGLLAFMAFLLVAAPYADGKISTQYLSGQGIFTSLITAIYATRVYAW
LKQHNVTIRLPKEVPTGVARSFEILIPVLVVIATLHPLNLFIEAQTGMIIPEAIMHLLAPLVSASDSLPAILLSVLMCQI
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGAALPHVYLQGFWDHYLLIGGVGSTLPLAFLLLRSRVAHLRTIGKMG
VVPSFFNINEPILFGAPIIMNPMLFIPFVFVPIINAILAYTATRLGWLAQVVSLTPWTTPAPIGASWAANWALSPVVMCI
ICMVMSALMYLPFLRAYERSLLKSEEQKAQDPVSVANAARSNS

Sequences:

>Translated_443_residues
MSSLYQSMVAVIEQSITPLAGKLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSAETTNSFARGWLDFSATYREQL
MLPFNLSMGVMTFFISVGIGASLGRQFNLDPIMSGLLAFMAFLLVAAPYADGKISTQYLSGQGIFTSLITAIYATRVYAW
LKQHNVTIRLPKEVPTGVARSFEILIPVLVVIATLHPLNLFIEAQTGMIIPEAIMHLLAPLVSASDSLPAILLSVLMCQI
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGAALPHVYLQGFWDHYLLIGGVGSTLPLAFLLLRSRVAHLRTIGKMG
VVPSFFNINEPILFGAPIIMNPMLFIPFVFVPIINAILAYTATRLGWLAQVVSLTPWTTPAPIGASWAANWALSPVVMCI
ICMVMSALMYLPFLRAYERSLLKSEEQKAQDPVSVANAARSNS
>Mature_442_residues
SSLYQSMVAVIEQSITPLAGKLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSAETTNSFARGWLDFSATYREQLM
LPFNLSMGVMTFFISVGIGASLGRQFNLDPIMSGLLAFMAFLLVAAPYADGKISTQYLSGQGIFTSLITAIYATRVYAWL
KQHNVTIRLPKEVPTGVARSFEILIPVLVVIATLHPLNLFIEAQTGMIIPEAIMHLLAPLVSASDSLPAILLSVLMCQIF
WFAGIHGSLIVTGIMNPFWMANLSANQAALAAGAALPHVYLQGFWDHYLLIGGVGSTLPLAFLLLRSRVAHLRTIGKMGV
VPSFFNINEPILFGAPIIMNPMLFIPFVFVPIINAILAYTATRLGWLAQVVSLTPWTTPAPIGASWAANWALSPVVMCII
CMVMSALMYLPFLRAYERSLLKSEEQKAQDPVSVANAARSNS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=458, Percent_Identity=29.9126637554585, Blast_Score=189, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 48305; Mature: 48174

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLYQSMVAVIEQSITPLAGKLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSAE
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
TTNSFARGWLDFSATYREQLMLPFNLSMGVMTFFISVGIGASLGRQFNLDPIMSGLLAFM
CCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHH
AFLLVAAPYADGKISTQYLSGQGIFTSLITAIYATRVYAWLKQHNVTIRLPKEVPTGVAR
HHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHH
SFEILIPVLVVIATLHPLNLFIEAQTGMIIPEAIMHLLAPLVSASDSLPAILLSVLMCQI
HHHHHHHHHHHHHHHCHHHEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGAALPHVYLQGFWDHYLLIGGVGSTLP
HHHHCCCCHHHHHHHCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHH
LAFLLLRSRVAHLRTIGKMGVVPSFFNINEPILFGAPIIMNPMLFIPFVFVPIINAILAY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHH
TATRLGWLAQVVSLTPWTTPAPIGASWAANWALSPVVMCIICMVMSALMYLPFLRAYERS
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKSEEQKAQDPVSVANAARSNS
HHHHHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure 
SSLYQSMVAVIEQSITPLAGKLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSAE
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
TTNSFARGWLDFSATYREQLMLPFNLSMGVMTFFISVGIGASLGRQFNLDPIMSGLLAFM
CCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHH
AFLLVAAPYADGKISTQYLSGQGIFTSLITAIYATRVYAWLKQHNVTIRLPKEVPTGVAR
HHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHH
SFEILIPVLVVIATLHPLNLFIEAQTGMIIPEAIMHLLAPLVSASDSLPAILLSVLMCQI
HHHHHHHHHHHHHHHCHHHEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGAALPHVYLQGFWDHYLLIGGVGSTLP
HHHHCCCCHHHHHHHCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHH
LAFLLLRSRVAHLRTIGKMGVVPSFFNINEPILFGAPIIMNPMLFIPFVFVPIINAILAY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHH
TATRLGWLAQVVSLTPWTTPAPIGASWAANWALSPVVMCIICMVMSALMYLPFLRAYERS
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKSEEQKAQDPVSVANAARSNS
HHHHHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]