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The map label for this gene is arcB [H]

Identifier: 218550493

GI number: 218550493

Start: 3270094

End: 3272430

Strand: Reverse

Name: arcB [H]

Synonym: EFER_3187

Alternate gene names: 218550493

Gene position: 3272430-3270094 (Counterclockwise)

Preceding gene: 218550494

Following gene: 218550492

Centisome position: 71.31

GC content: 48.18

Gene sequence:

>2337_bases
ATGAAGCAAATTCGTCTGCTGGCGCAGTACTATGTTGATCTGATGATGAAATTAGGTCTGGTGCGCTTCTCAATGCTGCT
GGCGCTGGCCCTCGTTGTACTCGCCATTGTGGTACAAATGGCAGTGACCATGGTGCTACATGGTCAGGTTGAAAGCATTG
ATGTTATTCGTTCTATTTTCTTTGGTCTGCTGATTACGCCGTGGGCGGTCTACTTTCTTTCGGTGGTCGTCGAGCAACTG
GAGGAGTCACGACAACGTCTGTCACGGCTGGTGCAAAAACTGGAGGAGATGCGCGAGCGCGATTTGAGCCTCAACGTTCA
GTTAAAAGATAATATTGCCCAGCTAAATCAGGAAATCGCCGTTCGTGAAAAAGCCGAAGCCGAGTTGCAGGAAACCTTTG
AACAACTGAAAATTGAAATTAAAGAGCGCGAAGAAACGCAGATCCAACTGGAACAGCAATCTTCTTTTTTACGTTCTTTC
CTCGATGCTTCGCCAGATCTGGTGTTTTATCGCAACGAAGATAAGGAGTTTTCAGGCTGTAACCGCGCAATGGAACTCCT
GACCGGAAAAAGCGAAAAGCAACTGGTACATCTGAAACCACAGGATGTGTATGCCCCGGATGTTGCTGAAAAGGTGATTG
AAACCGACGAAAAAGTTTTTCGCCACAACGTGTCACTCTCTTATGAACAGTGGTTACAGTACCCGGATGGGCGTAAAGCC
TGTTTTGAGATCCGGAAAGTGCCTTATTACGACCGGGTTGGTAAACGTCATGGGTTAATGGGATTTGGTCGCGATATTAC
AGAGCGCAAGCATTACCAGGATGCGCTGGAACAAGCCAGTCGCGATAAAACTACTTTTATTTCCACTATCAGCCACGAAT
TACGCACACCGCTTAACGGTATAGTAGGCCTGAGCCGAATTTTGCTGGATACCGATCTGAACGCCGAGCAGGAAAAATAT
CTTAAAACGATCCATGTTTCTGCAGTGACACTGGGTAATATCTTCAATGATATTATTGACATGGATAAAATTGAGCGTCG
CAAAGTCCAGCTTGATAATCAACCCATCGACTTCACCGGATTCCTTGCCGATTTAGAAAATCTTTCTGGCCTGCAGGCGC
AACAAAAAGGTCTGCGTTTTGTGATGGAGCCAACCTTACCGCTGCCGCATCAGGTGATTACCGATGGCACGCGTTTGCGT
CAGGTCTTGTGGAATCTTATCAGTAACGCCGTTAAGTTCACCCAGCAGGGCAAAGTTGAAGTGCGGGTTCGCTACGATAA
AGGTGAGATGCTGCACTTTGAAGTCGCCGATTCGGGGATCGGTATCCCGCAAGAAGAGCAGGATAAAATCTTTGCTATGT
ACTATCAGGTGAAGGATAGCCAGGGTGGAAAACCTGCTACCGGCACAGGGATCGGGCTTGCTGTATCTCGCCGTCTGGCG
CGGGATATGGGCGGCGATATTAGTGTTTCCAGCGTACCGGGGCAGGGTTCGGTGTTTACCCTAACCGTGCGTGCACCAGC
GGTAGCTGAAGAAGTTGACGATGTGTTCGAAGAAGATGATCTGCCGCTGCCAGCGTTAAATGTGTTACTGGTGGAGGATA
TCGAATTAAACGTTATTGTTGCCCGTTCAGTGCTGGAGAAATTAGGCAATAGTGTTGATGTGGCAATGACAGGTAAAGCG
GCGCTGGAGATGTTTAAGCCAGGCGAGTATGACCTGGTGTTGTTGGATATCCAACTGCCAGATATGACTGGCCTTGATAT
TTCTCGCGAGTTAACTCGCCGCTACTCTCGTGATGATTTACCACCGCTGGTGGCACTTACTGCCAACGTACTGAAAGATA
AAAAAGAGTACCTGGATGCCGGGATGGATGATGTGCTGAGTAAGCCGCTGTCCGTTCCGGCATTAACCGCGATGATCAAA
AAGTTCTGGGATACTCAGGACGAAGAGGAGAGCACGGTGGCACCTGATGACAATAGCAAATCGCAAGAGTTACTTGATAT
TCCAATGTTGGAACAATATCTCGAACTTGTTGGACCGAAGCTAATTACCGATGGTCTTGCTGTCTTCGAGAAGATGATGC
CCGGATATATGAGCGTGTTGCAGTCTAATCTGACTGCGCGCGATCAAAAAGGCATTGTTGAGGAAGGGCATAAAATCAAA
GGTGCAGCGGGTTCCGTTGGGCTTCGTCACTTACAGCAACTGGGGCAGCAAATTCAGTCACCGGATCTCCCGGCATGGGA
AGATAACGTTGGTGAATGGATTGAAGAGATGAAACAAGAGTGGCGTCACGATGTTGAAGTGCTGAAAGCGTGGGTGGCAA
AGAACGGAAAAAAATGA

Upstream 100 bases:

>100_bases
CTTTAGTTGATGCGGGGAATTCCGCATTTCTCACACAATTTTCAACGTAACTGTCAGAATTGGGTATTATTGTGGCAGGT
TGTCGTTAAGGAATTCCCCA

Downstream 100 bases:

>100_bases
CCCCGGATTAACCGGGGTGCGCGAATACTGCGCCAACACCAGGGAAATTATGGCTGCGCCGTAAATTATTGTCGTTTGTA
ACCAAGGCGCAGCACTGTTT

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLSLNVQLKDNIAQLNQEIAVREKAEAELQETFEQLKIEIKEREETQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPQDVYAPDVAEKVIETDEKVFRHNVSLSYEQWLQYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKHYQDALEQASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLNAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKIERRKVQLDNQPIDFTGFLADLENLSGLQAQQKGLRFVMEPTLPLPHQVITDGTRLR
QVLWNLISNAVKFTQQGKVEVRVRYDKGEMLHFEVADSGIGIPQEEQDKIFAMYYQVKDSQGGKPATGTGIGLAVSRRLA
RDMGGDISVSSVPGQGSVFTLTVRAPAVAEEVDDVFEEDDLPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFKPGEYDLVLLDIQLPDMTGLDISRELTRRYSRDDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDTQDEEESTVAPDDNSKSQELLDIPMLEQYLELVGPKLITDGLAVFEKMMPGYMSVLQSNLTARDQKGIVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVGEWIEEMKQEWRHDVEVLKAWVAKNGKK

Sequences:

>Translated_778_residues
MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLSLNVQLKDNIAQLNQEIAVREKAEAELQETFEQLKIEIKEREETQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPQDVYAPDVAEKVIETDEKVFRHNVSLSYEQWLQYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKHYQDALEQASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLNAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKIERRKVQLDNQPIDFTGFLADLENLSGLQAQQKGLRFVMEPTLPLPHQVITDGTRLR
QVLWNLISNAVKFTQQGKVEVRVRYDKGEMLHFEVADSGIGIPQEEQDKIFAMYYQVKDSQGGKPATGTGIGLAVSRRLA
RDMGGDISVSSVPGQGSVFTLTVRAPAVAEEVDDVFEEDDLPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFKPGEYDLVLLDIQLPDMTGLDISRELTRRYSRDDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDTQDEEESTVAPDDNSKSQELLDIPMLEQYLELVGPKLITDGLAVFEKMMPGYMSVLQSNLTARDQKGIVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVGEWIEEMKQEWRHDVEVLKAWVAKNGKK
>Mature_778_residues
MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLSLNVQLKDNIAQLNQEIAVREKAEAELQETFEQLKIEIKEREETQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPQDVYAPDVAEKVIETDEKVFRHNVSLSYEQWLQYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKHYQDALEQASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLNAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKIERRKVQLDNQPIDFTGFLADLENLSGLQAQQKGLRFVMEPTLPLPHQVITDGTRLR
QVLWNLISNAVKFTQQGKVEVRVRYDKGEMLHFEVADSGIGIPQEEQDKIFAMYYQVKDSQGGKPATGTGIGLAVSRRLA
RDMGGDISVSSVPGQGSVFTLTVRAPAVAEEVDDVFEEDDLPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFKPGEYDLVLLDIQLPDMTGLDISRELTRRYSRDDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDTQDEEESTVAPDDNSKSQELLDIPMLEQYLELVGPKLITDGLAVFEKMMPGYMSVLQSNLTARDQKGIVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVGEWIEEMKQEWRHDVEVLKAWVAKNGKK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=778, Percent_Identity=92.2879177377892, Blast_Score=1452, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=658, Percent_Identity=27.5075987841945, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI87081816, Length=516, Percent_Identity=28.2945736434109, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1789149, Length=423, Percent_Identity=29.7872340425532, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=39.1666666666667, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788549, Length=423, Percent_Identity=25.531914893617, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=30.4147465437788, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786600, Length=275, Percent_Identity=26.9090909090909, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=28.3400809716599, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1790346, Length=205, Percent_Identity=28.2926829268293, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=222, Percent_Identity=26.1261261261261, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=23.8493723849372, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=23.5023041474654, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=23.2758620689655, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=217, Percent_Identity=26.2672811059908, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=153, Percent_Identity=34.640522875817, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88086; Mature: 88086

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDLSLNVQLKDNIAQLNQEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
VREKAEAELQETFEQLKIEIKEREETQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGC
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLVHLKPQDVYAPDVAEKVIETDEKVFRHNVSLSYEQWLQYPDGRKA
HHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHH
CFEIRKVPYYDRVGKRHGLMGFGRDITERKHYQDALEQASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTDLNAEQEKYLKTIHVSAVTLGNIFNDIIDMDKIERRKVQLDNQPIDFTG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FLADLENLSGLQAQQKGLRFVMEPTLPLPHQVITDGTRLRQVLWNLISNAVKFTQQGKVE
HHHHHHHCCCCHHHHHCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEE
VRVRYDKGEMLHFEVADSGIGIPQEEQDKIFAMYYQVKDSQGGKPATGTGIGLAVSRRLA
EEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
RDMGGDISVSSVPGQGSVFTLTVRAPAVAEEVDDVFEEDDLPLPALNVLLVEDIELNVIV
HHCCCCEEEECCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHEEEEECCCCHHHH
ARSVLEKLGNSVDVAMTGKAALEMFKPGEYDLVLLDIQLPDMTGLDISRELTRRYSRDDL
HHHHHHHCCCCEEEEECCHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCC
PPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKKFWDTQDEEESTVAPDDNSK
CHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SQELLDIPMLEQYLELVGPKLITDGLAVFEKMMPGYMSVLQSNLTARDQKGIVEEGHKIK
CHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCCCC
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVGEWIEEMKQEWRHDVEVLKAWVAKNGKK
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDLSLNVQLKDNIAQLNQEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
VREKAEAELQETFEQLKIEIKEREETQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGC
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLVHLKPQDVYAPDVAEKVIETDEKVFRHNVSLSYEQWLQYPDGRKA
HHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHH
CFEIRKVPYYDRVGKRHGLMGFGRDITERKHYQDALEQASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTDLNAEQEKYLKTIHVSAVTLGNIFNDIIDMDKIERRKVQLDNQPIDFTG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FLADLENLSGLQAQQKGLRFVMEPTLPLPHQVITDGTRLRQVLWNLISNAVKFTQQGKVE
HHHHHHHCCCCHHHHHCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEE
VRVRYDKGEMLHFEVADSGIGIPQEEQDKIFAMYYQVKDSQGGKPATGTGIGLAVSRRLA
EEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
RDMGGDISVSSVPGQGSVFTLTVRAPAVAEEVDDVFEEDDLPLPALNVLLVEDIELNVIV
HHCCCCEEEECCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHEEEEECCCCHHHH
ARSVLEKLGNSVDVAMTGKAALEMFKPGEYDLVLLDIQLPDMTGLDISRELTRRYSRDDL
HHHHHHHCCCCEEEEECCHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCC
PPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKKFWDTQDEEESTVAPDDNSK
CHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SQELLDIPMLEQYLELVGPKLITDGLAVFEKMMPGYMSVLQSNLTARDQKGIVEEGHKIK
CHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCCCCCC
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVGEWIEEMKQEWRHDVEVLKAWVAKNGKK
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]