Click here to switch to the map view.

The map label for this gene is lptA [H]

Identifier: 218550483

GI number: 218550483

Start: 3262804

End: 3263361

Strand: Direct

Name: lptA [H]

Synonym: EFER_3177

Alternate gene names: 218550483

Gene position: 3262804-3263361 (Clockwise)

Preceding gene: 218550482

Following gene: 218550484

Centisome position: 71.11

GC content: 48.92

Gene sequence:

>558_bases
ATGAAATTCAAAATAAACAAACACAGCCTTAATCTTGCGCTTGCCAGCGCACTTCTGGCCGCCAGTATTCCGGCCCTCGC
CGTAACTGGTGACACTGAACAGCCGATTCATATTGAATCTGATCAGCAGTCTCTGGATATGCAGGGAAACGTCGTGACCT
TCACCGGTAATGTCGTCGTGACCCAGGGCACCATTAAGATCAATGCCGATAAAGTGGTCGTCACCCGTCCGGGTGGTGAA
CAAGGTAAGGAAGTGATCGACGGTTACGGTAACCCGGCCACCTTCTATCAAATGCAGGATAACGGTAAACCGGTCGAAGG
TCATGCCTCCAAGATGCACTACGAACTGGCGAAAGATTTCGTCGTGCTCACTGGTAATGCTTATCTACAACAAGTCGATA
GCAACATTAAAGGCGACAAGATCACTTACCTGGTGAAAGAACAGAAAATGCAGGCCTTCAGCGATAAAGGCAAACGCGTA
ACCACCGTTCTGGTGCCATCGCAATTGCAGGATAAAAACAATAAAGGCCAGGCCCCGGCGCAGAAAAAGGGTAATTAA

Upstream 100 bases:

>100_bases
GTCACGTTATACGGTACGACATTTAACTCCAGCGGCCTGAAAATGCGCGGCAACTTACGCAGCAAGAACGCCGAGCTGAT
TGAAAAGGTTAGAACCTCAT

Downstream 100 bases:

>100_bases
TTCGTTATGGCAACATTAACTGCAAAAAACCTGGCAAAAGCGTACAAAGGTCGCCGCGTCGTAGAAGACGTCAGCCTGAC
CGTAAACTCTGGTGAAATTG

Product: lipopolysaccharide transport periplasmic protein LptA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKFKINKHSLNLALASALLAASIPALAVTGDTEQPIHIESDQQSLDMQGNVVTFTGNVVVTQGTIKINADKVVVTRPGGE
QGKEVIDGYGNPATFYQMQDNGKPVEGHASKMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
TTVLVPSQLQDKNNKGQAPAQKKGN

Sequences:

>Translated_185_residues
MKFKINKHSLNLALASALLAASIPALAVTGDTEQPIHIESDQQSLDMQGNVVTFTGNVVVTQGTIKINADKVVVTRPGGE
QGKEVIDGYGNPATFYQMQDNGKPVEGHASKMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
TTVLVPSQLQDKNNKGQAPAQKKGN
>Mature_185_residues
MKFKINKHSLNLALASALLAASIPALAVTGDTEQPIHIESDQQSLDMQGNVVTFTGNVVVTQGTIKINADKVVVTRPGGE
QGKEVIDGYGNPATFYQMQDNGKPVEGHASKMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
TTVLVPSQLQDKNNKGQAPAQKKGN

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=185, Percent_Identity=94.5945945945946, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 20041; Mature: 20041

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKINKHSLNLALASALLAASIPALAVTGDTEQPIHIESDQQSLDMQGNVVTFTGNVVV
CEEEECHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCCCCCEEEEECCEEE
TQGTIKINADKVVVTRPGGEQGKEVIDGYGNPATFYQMQDNGKPVEGHASKMHYELAKDF
EECEEEECCCEEEEECCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCE
VVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRVTTVLVPSQLQDKNNKGQAPA
EEEECCHHHHHHCCCCCCCEEEEEEEHHHHHHHHCCCCEEEEEEECCHHCCCCCCCCCCC
QKKGN
CCCCC
>Mature Secondary Structure
MKFKINKHSLNLALASALLAASIPALAVTGDTEQPIHIESDQQSLDMQGNVVTFTGNVVV
CEEEECHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCCCCCEEEEECCEEE
TQGTIKINADKVVVTRPGGEQGKEVIDGYGNPATFYQMQDNGKPVEGHASKMHYELAKDF
EECEEEECCCEEEEECCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCE
VVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRVTTVLVPSQLQDKNNKGQAPA
EEEECCHHHHHHCCCCCCCEEEEEEEHHHHHHHHCCCCEEEEEEECCHHCCCCCCCCCCC
QKKGN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]