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The map label for this gene is appA [H]

Identifier: 218550351

GI number: 218550351

Start: 3116107

End: 3117393

Strand: Direct

Name: appA [H]

Synonym: EFER_3043

Alternate gene names: 218550351

Gene position: 3116107-3117393 (Clockwise)

Preceding gene: 218550350

Following gene: 218550352

Centisome position: 67.91

GC content: 51.59

Gene sequence:

>1287_bases
ATGTCTGCATCACTTATCCGCATTATCTGTGTGATGACGTTATTAGCAGCATTTCCCACTCGTGCAGAGCAAAACGATGG
CCTGCAACTACAGAGTGTGGTTATCGTCAGCCGTCACGGAGTGAGGGCCCCCACTAAACTCACCCCACTAATGCAAAATG
TTACCCCTGATACCTGGCCGCAATGGTCTGTTCCGCTGGGTTGGTTAACCCCGCGTGGTGGCGAACTCATTTCGTTGCTG
GGAGATTATCAACGCCAACGGTTAATTTCCGAAGGCCTGATAAACGCAGCACAGTGCCCGTCTGCAAAGCAGGTTGCCGT
GATTGCCGACACTGACGAGCGTACACGTAAAACAGGCGAAGCCTTTATCTCTGCGCTGGCACCACATTGCGCGCTCCCCG
TTCATGTTCAGCAAAATCTCCGGCAGACTGATCCTCTTTTTAACCCACTGAAAACCGGACATTGCCAACTGGATAAACCC
ACGGTGCGCGCAGCCATACTTAAGCAAGCGGGAGGTAGTATTGAAGCATTAAATAAACAGTATCAGCCTGCTTTTACAAC
GCTTGCTGATGTACTTAATTTACGGGAATCTCCCCTTTGCCAACAAGAGAAACGCTGCACATTACCAGAAGCGCTGCCCT
CTGAACTGGAAGTCAGCAAACGGAATGTCTCATTTAGCGGCGCGTGGGGATTGGCCTCAACCGTTAGCGAGATCTTTCTT
TTACAGCAAGCTCAGGGAATGGCAGATCCAGGATGGGGGCGGATTAAGAATTCAGAGCAGTGGCAACAGTTGCTGAGTTT
GCATAATGCCCAGTTTGATCTGTTGCAACGTACCCCGGAAGTCGCCAGCAGTCGTGCCACTCCGCTGTTGGATCTGATTA
TCGCCACACTGACACCGGGTCATGCGGGTAAGCAGATGGCAGGGATTTCACTTCCCACATCACTGCTGTTTATTGCCGGT
CATGATACGAATCTTGCCAATCTCGGTGGAGCGCTTGGGATGAGCTGGACATTACCCGGCCAACCCGATAATACTCCGCC
TGGTGGTGAACTGGTTTTTGAACGCTGGCACCGGGCAACCGATAACACCGACTGGATTCAGGTTTCGTTGGTGTATCAAA
CGTTACAACAGATGCGTAATGTGACGCGGTTATCCATGACCACGCCTCCCGGAAAAGTGCCATTAACGGTGAATGGCTGC
CAGGAAACCAACAGCCAGGGGATGTGTTCCCTGAAAAGTTTTACGGCGGTGATTAACACCATCAGAAATCCGGCGTGTGC
GCTGTGA

Upstream 100 bases:

>100_bases
CAAAAAGAGTGATGACCTTGCCTGGGAACAGGGCAATAAATGATACCCTGCGCTCCAGATGGTGTTAGTGAAAAGCGTCA
GGGATTAAGGAGATATTAAG

Downstream 100 bases:

>100_bases
AAATTATCTTTAAAAAGATGAAGTGAGGCTGATGGTAAACGATGCGCTACGCTTATCAGCCTCATACAACCACTACAACA
TATTGAATTTCAAATAGTTA

Product: phosphoanhydride phosphorylase

Products: NA

Alternate protein names: Phosphoanhydride phosphohydrolase; pH 2.5 acid phosphatase; AP; 4-phytase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSASLIRIICVMTLLAAFPTRAEQNDGLQLQSVVIVSRHGVRAPTKLTPLMQNVTPDTWPQWSVPLGWLTPRGGELISLL
GDYQRQRLISEGLINAAQCPSAKQVAVIADTDERTRKTGEAFISALAPHCALPVHVQQNLRQTDPLFNPLKTGHCQLDKP
TVRAAILKQAGGSIEALNKQYQPAFTTLADVLNLRESPLCQQEKRCTLPEALPSELEVSKRNVSFSGAWGLASTVSEIFL
LQQAQGMADPGWGRIKNSEQWQQLLSLHNAQFDLLQRTPEVASSRATPLLDLIIATLTPGHAGKQMAGISLPTSLLFIAG
HDTNLANLGGALGMSWTLPGQPDNTPPGGELVFERWHRATDNTDWIQVSLVYQTLQQMRNVTRLSMTTPPGKVPLTVNGC
QETNSQGMCSLKSFTAVINTIRNPACAL

Sequences:

>Translated_428_residues
MSASLIRIICVMTLLAAFPTRAEQNDGLQLQSVVIVSRHGVRAPTKLTPLMQNVTPDTWPQWSVPLGWLTPRGGELISLL
GDYQRQRLISEGLINAAQCPSAKQVAVIADTDERTRKTGEAFISALAPHCALPVHVQQNLRQTDPLFNPLKTGHCQLDKP
TVRAAILKQAGGSIEALNKQYQPAFTTLADVLNLRESPLCQQEKRCTLPEALPSELEVSKRNVSFSGAWGLASTVSEIFL
LQQAQGMADPGWGRIKNSEQWQQLLSLHNAQFDLLQRTPEVASSRATPLLDLIIATLTPGHAGKQMAGISLPTSLLFIAG
HDTNLANLGGALGMSWTLPGQPDNTPPGGELVFERWHRATDNTDWIQVSLVYQTLQQMRNVTRLSMTTPPGKVPLTVNGC
QETNSQGMCSLKSFTAVINTIRNPACAL
>Mature_427_residues
SASLIRIICVMTLLAAFPTRAEQNDGLQLQSVVIVSRHGVRAPTKLTPLMQNVTPDTWPQWSVPLGWLTPRGGELISLLG
DYQRQRLISEGLINAAQCPSAKQVAVIADTDERTRKTGEAFISALAPHCALPVHVQQNLRQTDPLFNPLKTGHCQLDKPT
VRAAILKQAGGSIEALNKQYQPAFTTLADVLNLRESPLCQQEKRCTLPEALPSELEVSKRNVSFSGAWGLASTVSEIFLL
QQAQGMADPGWGRIKNSEQWQQLLSLHNAQFDLLQRTPEVASSRATPLLDLIIATLTPGHAGKQMAGISLPTSLLFIAGH
DTNLANLGGALGMSWTLPGQPDNTPPGGELVFERWHRATDNTDWIQVSLVYQTLQQMRNVTRLSMTTPPGKVPLTVNGCQ
ETNSQGMCSLKSFTAVINTIRNPACAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histidine acid phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1787215, Length=432, Percent_Identity=64.1203703703704, Blast_Score=553, Evalue=1e-158,
Organism=Escherichia coli, GI1787237, Length=426, Percent_Identity=32.3943661971831, Blast_Score=231, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000560 [H]

Pfam domain/function: PF00328 Acid_phosphat_A [H]

EC number: =3.1.3.2; =3.1.3.26 [H]

Molecular weight: Translated: 46609; Mature: 46478

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00616 HIS_ACID_PHOSPHAT_1 ; PS00778 HIS_ACID_PHOSPHAT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASLIRIICVMTLLAAFPTRAEQNDGLQLQSVVIVSRHGVRAPTKLTPLMQNVTPDTWP
CCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCC
QWSVPLGWLTPRGGELISLLGDYQRQRLISEGLINAAQCPSAKQVAVIADTDERTRKTGE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCCHHHHHHHH
AFISALAPHCALPVHVQQNLRQTDPLFNPLKTGHCQLDKPTVRAAILKQAGGSIEALNKQ
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHCCCCHHHHHHH
YQPAFTTLADVLNLRESPLCQQEKRCTLPEALPSELEVSKRNVSFSGAWGLASTVSEIFL
CCHHHHHHHHHHHCCCCCCCCHHHCCCCHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
LQQAQGMADPGWGRIKNSEQWQQLLSLHNAQFDLLQRTPEVASSRATPLLDLIIATLTPG
HHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCHHHHHCCCCHHHHHHHHHCCCC
HAGKQMAGISLPTSLLFIAGHDTNLANLGGALGMSWTLPGQPDNTPPGGELVFERWHRAT
CCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCC
DNTDWIQVSLVYQTLQQMRNVTRLSMTTPPGKVPLTVNGCQETNSQGMCSLKSFTAVINT
CCCCEEEHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
IRNPACAL
HCCCCCCC
>Mature Secondary Structure 
SASLIRIICVMTLLAAFPTRAEQNDGLQLQSVVIVSRHGVRAPTKLTPLMQNVTPDTWP
CCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCC
QWSVPLGWLTPRGGELISLLGDYQRQRLISEGLINAAQCPSAKQVAVIADTDERTRKTGE
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCEEEEEECCCHHHHHHHH
AFISALAPHCALPVHVQQNLRQTDPLFNPLKTGHCQLDKPTVRAAILKQAGGSIEALNKQ
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHCCCCHHHHHHH
YQPAFTTLADVLNLRESPLCQQEKRCTLPEALPSELEVSKRNVSFSGAWGLASTVSEIFL
CCHHHHHHHHHHHCCCCCCCCHHHCCCCHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
LQQAQGMADPGWGRIKNSEQWQQLLSLHNAQFDLLQRTPEVASSRATPLLDLIIATLTPG
HHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCHHHHHCCCCHHHHHHHHHCCCC
HAGKQMAGISLPTSLLFIAGHDTNLANLGGALGMSWTLPGQPDNTPPGGELVFERWHRAT
CCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCC
DNTDWIQVSLVYQTLQQMRNVTRLSMTTPPGKVPLTVNGCQETNSQGMCSLKSFTAVINT
CCCCEEEHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
IRNPACAL
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2168385; 8905232; 9278503; 3038201; 1658595; 8387749; 10696472; 1429631; 10655611 [H]