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The map label for this gene is uxuR [H]

Identifier: 218550336

GI number: 218550336

Start: 3099562

End: 3100335

Strand: Reverse

Name: uxuR [H]

Synonym: EFER_3028

Alternate gene names: 218550336

Gene position: 3100335-3099562 (Counterclockwise)

Preceding gene: 218550337

Following gene: 218550335

Centisome position: 67.56

GC content: 49.48

Gene sequence:

>774_bases
ATGAAATCAGGCACTTCTGCGCAAAGACCTTACCAGGAAGTAGGGGCGATGATCCGCGATCTCATCATCAAAACGCCTTA
TAAGCCCGGCGATCGCTTGCCACCTGAGCGGGAGATCGCTGAAATGCTTGATGTCACCCGTACCGTTGTGCGTGAAGCGC
TGATCATGCTGGAAATTAAAGGCCTGGTGGAAGTCCGTCGGGGTGCCGGGATCTACGTCCTCGATAGCGACAGTGAACAG
GTAATCGATACGCCAGATGTCAATGTTTGTAATGATGCCGGTCCGTTTGAATTACTACAGGCACGCCAGTTGCTGGAGAG
TAATATCGCCGAGTTTGCCGCTTTACAGGCCACCCGTGAAGATATTGTTAAAATGCGCCAGGCGTTGCAACTGGAAGAGC
GTGAACTGGCTTCCAGTGGACCGGGAAGTAGTGAAAGCGGCGATATGCAATTTCATCTCGCTATTGCAGAAGCGACGCAC
AATAGCATGTTAGTTGAATTGTTCCGCCAGTCCTGGCAGTGGCGCGAAAATAATCCAATGTGGATTCAGGTGCATAGTCA
TCTTGATGATAGTCTGTATCGCAAGGAGTGGCTGAAAGATCACAAACAGATCCTCGCAGCATTAATCAAGAAAGATGCCC
GAGCAGCAAAACTGGCGATGTGGCAGCATCTGGAAAACGTTAAACAGCGGCTGCTGGAGTTTTCTAATGTTGATGATATC
TACTTTGATGGCTACCTGTTTGATTCCTGGCCACTGGATAAAGTTGACACCTGA

Upstream 100 bases:

>100_bases
AGTCATAATTTATTGAGTATGAACTCTTTGTTGGCTGGATCAGGCGTAAATACTGCTTTCGGCAATAATTCGATTAATCG
CACCTAACGGACACAACATC

Downstream 100 bases:

>100_bases
TAAATTTCAGACCATATGAAACCTTTGCTGAATATAGCGAAGGTTTTTTTATACGCTCTAAATTATTATTTAATAACGTT
CTGATATATTAACCCTGAAA

Product: DNA-binding transcriptional repressor UxuR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKSGTSAQRPYQEVGAMIRDLIIKTPYKPGDRLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSDSEQ
VIDTPDVNVCNDAGPFELLQARQLLESNIAEFAALQATREDIVKMRQALQLEERELASSGPGSSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWIQVHSHLDDSLYRKEWLKDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFDSWPLDKVDT

Sequences:

>Translated_257_residues
MKSGTSAQRPYQEVGAMIRDLIIKTPYKPGDRLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSDSEQ
VIDTPDVNVCNDAGPFELLQARQLLESNIAEFAALQATREDIVKMRQALQLEERELASSGPGSSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWIQVHSHLDDSLYRKEWLKDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFDSWPLDKVDT
>Mature_257_residues
MKSGTSAQRPYQEVGAMIRDLIIKTPYKPGDRLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSDSEQ
VIDTPDVNVCNDAGPFELLQARQLLESNIAEFAALQATREDIVKMRQALQLEERELASSGPGSSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWIQVHSHLDDSLYRKEWLKDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFDSWPLDKVDT

Specific function: Repressor for the uxuRBA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=257, Percent_Identity=94.1634241245136, Blast_Score=502, Evalue=1e-144,
Organism=Escherichia coli, GI87082208, Length=256, Percent_Identity=47.265625, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1790032, Length=232, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786303, Length=224, Percent_Identity=33.4821428571429, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789353, Length=248, Percent_Identity=30.241935483871, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI48994955, Length=188, Percent_Identity=28.1914893617021, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29480; Mature: 29480

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00018 EF_HAND_1 ; PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGTSAQRPYQEVGAMIRDLIIKTPYKPGDRLPPEREIAEMLDVTRTVVREALIMLEIK
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLVEVRRGAGIYVLDSDSEQVIDTPDVNVCNDAGPFELLQARQLLESNIAEFAALQATRE
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DIVKMRQALQLEERELASSGPGSSESGDMQFHLAIAEATHNSMLVELFRQSWQWRENNPM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCE
WIQVHSHLDDSLYRKEWLKDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
YFDGYLFDSWPLDKVDT
EECCEEECCCCCCCCCC
>Mature Secondary Structure
MKSGTSAQRPYQEVGAMIRDLIIKTPYKPGDRLPPEREIAEMLDVTRTVVREALIMLEIK
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLVEVRRGAGIYVLDSDSEQVIDTPDVNVCNDAGPFELLQARQLLESNIAEFAALQATRE
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DIVKMRQALQLEERELASSGPGSSESGDMQFHLAIAEATHNSMLVELFRQSWQWRENNPM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCE
WIQVHSHLDDSLYRKEWLKDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
YFDGYLFDSWPLDKVDT
EECCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]