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The map label for this gene is qseC [H]

Identifier: 218550276

GI number: 218550276

Start: 3037301

End: 3038656

Strand: Direct

Name: qseC [H]

Synonym: EFER_2968

Alternate gene names: 218550276

Gene position: 3037301-3038656 (Clockwise)

Preceding gene: 218550275

Following gene: 218550277

Centisome position: 66.19

GC content: 50.44

Gene sequence:

>1356_bases
ATGAAATTCACACAACGCCTTAGCCTGCGCATCAGGCTGACGCTTATTTTTTTAATTCTGGCTTCCATGACCTGGCTTGT
TTCTGGCTTTATTGCCTGGAAGCTGACCGCTGATAACGTTGACGAGCTATTTGATACCCAACAAATGCTGTTTGCAAAAC
GGCTTATCGCATTAGATATCAATGAACTACGCGCTTCCGAGCGTATCGCACAAACACCCAAAAAATTCAAACATGGTCAT
ATTGATGACGATGTGCTGGCTTTCGCTGTTTTCACCCGTGACGGAAAAATGGTGATGAATGATGGTGACAATGGGCGATA
CATTCCCTACAGCTATCATCGGGAAGGCTTTGATGATGGACAATTGACGAACGATGACGATAGCTGGCGTTTTATCTGGC
TGACTTCTGCTGACGGAAAATACCGCATTGTGGTGGGTCAGGAGTGGGAATATCGGGAAGAGATGGCACTGGGGATTGTG
CTGGCGCAATTAGTACCGTGGCTGGTGGCCCTGCCATTAATGCTGCTTATATTACTGTTTGCCCTCGGTCGTGAGCTGAA
ACCACTACAAAAAATAGCTGCGGCTCTGCGTTTGCGTGACCCGGAGTCTGCCCAACCACTCGACACAACCGGTGTACCAT
GCGAAGTACGTCCCCTGGTTGACTCACTAAACCAACTTTTTGCTCGTATACATACTGTTATGGTACGCGAGCGACGATTT
ACATCCGATGCCGCCCATGAACTGCGTAGCCCTTTAACAGCGCTAAAAGTGCAAACCGAAGTGGCGCAACTTTCCGTGGA
CGATCCGCAAGTCCGAGACAAAGCGCTGATGCAGCTGCATGAAGGGATCGAGCGTGCAACTCGTTTGGTGGATCAGTTGT
TAACGCTTTCTCGTCTGGACTCACTGGACAATCTTCAGGATGTAGCAGAAATCTCTTTTGATGACCTGCTGCAATCAGCA
GTAATGGATATTTACCATACCGCTCAACAGGCACAAATTGATGTACGTCTGGCACTCAACGCCCAGGGCATCATACGAAC
GGGGCAGCCTCTGCTGCTCAGCCTGCTGGTACGAAATTTGCTGGATAACGCGGTTCGCTATAGCCCACCGGGTAGCGTGG
TGGAAGTCACCCTCAATACGCACAGTTTTACGGTGAAAGACAACGGCCCCGGCGTGTCAGAGGAAGCACTGGAGCATATT
GGTGAACGCTTTTATCGCCCACCTGGACAAACAGCTACCGGCAGTGGGCTGGGGCTTTCGATTGTCCGCCGGATCGCCAG
ACTGCACGGCCTTCAGGTCACTTTTGGTAATGCGGAACAGGGTGGGTTTGAAGCGAAGGTGAGTTGGAAAACTTGA

Upstream 100 bases:

>100_bases
CCAGTAATGCCGTAGAAGTCCATATTCATCACCTGCGGCGTAAACTCGGCAGCGGGTTTATCCGCACTGTTCATGGTATT
GGTTACACGTTAGGTGAGGC

Downstream 100 bases:

>100_bases
GATTTTTGCCAAATCTGCAAAAGACTTTGCACATTTTGCCAATTTTACCGACGCGCCAGCTGGCGTAATATGATCCTCAA
ACGTTTCTTTCGAGGATAAA

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKFTQRLSLRIRLTLIFLILASMTWLVSGFIAWKLTADNVDELFDTQQMLFAKRLIALDINELRASERIAQTPKKFKHGH
IDDDVLAFAVFTRDGKMVMNDGDNGRYIPYSYHREGFDDGQLTNDDDSWRFIWLTSADGKYRIVVGQEWEYREEMALGIV
LAQLVPWLVALPLMLLILLFALGRELKPLQKIAAALRLRDPESAQPLDTTGVPCEVRPLVDSLNQLFARIHTVMVRERRF
TSDAAHELRSPLTALKVQTEVAQLSVDDPQVRDKALMQLHEGIERATRLVDQLLTLSRLDSLDNLQDVAEISFDDLLQSA
VMDIYHTAQQAQIDVRLALNAQGIIRTGQPLLLSLLVRNLLDNAVRYSPPGSVVEVTLNTHSFTVKDNGPGVSEEALEHI
GERFYRPPGQTATGSGLGLSIVRRIARLHGLQVTFGNAEQGGFEAKVSWKT

Sequences:

>Translated_451_residues
MKFTQRLSLRIRLTLIFLILASMTWLVSGFIAWKLTADNVDELFDTQQMLFAKRLIALDINELRASERIAQTPKKFKHGH
IDDDVLAFAVFTRDGKMVMNDGDNGRYIPYSYHREGFDDGQLTNDDDSWRFIWLTSADGKYRIVVGQEWEYREEMALGIV
LAQLVPWLVALPLMLLILLFALGRELKPLQKIAAALRLRDPESAQPLDTTGVPCEVRPLVDSLNQLFARIHTVMVRERRF
TSDAAHELRSPLTALKVQTEVAQLSVDDPQVRDKALMQLHEGIERATRLVDQLLTLSRLDSLDNLQDVAEISFDDLLQSA
VMDIYHTAQQAQIDVRLALNAQGIIRTGQPLLLSLLVRNLLDNAVRYSPPGSVVEVTLNTHSFTVKDNGPGVSEEALEHI
GERFYRPPGQTATGSGLGLSIVRRIARLHGLQVTFGNAEQGGFEAKVSWKT
>Mature_451_residues
MKFTQRLSLRIRLTLIFLILASMTWLVSGFIAWKLTADNVDELFDTQQMLFAKRLIALDINELRASERIAQTPKKFKHGH
IDDDVLAFAVFTRDGKMVMNDGDNGRYIPYSYHREGFDDGQLTNDDDSWRFIWLTSADGKYRIVVGQEWEYREEMALGIV
LAQLVPWLVALPLMLLILLFALGRELKPLQKIAAALRLRDPESAQPLDTTGVPCEVRPLVDSLNQLFARIHTVMVRERRF
TSDAAHELRSPLTALKVQTEVAQLSVDDPQVRDKALMQLHEGIERATRLVDQLLTLSRLDSLDNLQDVAEISFDDLLQSA
VMDIYHTAQQAQIDVRLALNAQGIIRTGQPLLLSLLVRNLLDNAVRYSPPGSVVEVTLNTHSFTVKDNGPGVSEEALEHI
GERFYRPPGQTATGSGLGLSIVRRIARLHGLQVTFGNAEQGGFEAKVSWKT

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=449, Percent_Identity=79.0645879732739, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1790551, Length=308, Percent_Identity=31.8181818181818, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=28.3333333333333, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786783, Length=335, Percent_Identity=28.6567164179104, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=32.6271186440678, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=275, Percent_Identity=29.0909090909091, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788393, Length=240, Percent_Identity=28.75, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=29.1497975708502, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786912, Length=214, Percent_Identity=30.3738317757009, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789808, Length=288, Percent_Identity=26.0416666666667, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=29.5652173913043, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50762; Mature: 50762

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTQRLSLRIRLTLIFLILASMTWLVSGFIAWKLTADNVDELFDTQQMLFAKRLIALDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHH
NELRASERIAQTPKKFKHGHIDDDVLAFAVFTRDGKMVMNDGDNGRYIPYSYHREGFDDG
HHHHHHHHHHHCHHHHCCCCCCCHHHEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCC
QLTNDDDSWRFIWLTSADGKYRIVVGQEWEYREEMALGIVLAQLVPWLVALPLMLLILLF
CCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGRELKPLQKIAAALRLRDPESAQPLDTTGVPCEVRPLVDSLNQLFARIHTVMVRERRF
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLTALKVQTEVAQLSVDDPQVRDKALMQLHEGIERATRLVDQLLTLSRLD
CHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLDNLQDVAEISFDDLLQSAVMDIYHTAQQAQIDVRLALNAQGIIRTGQPLLLSLLVRNL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEECCHHHHHHHHHHHH
LDNAVRYSPPGSVVEVTLNTHSFTVKDNGPGVSEEALEHIGERFYRPPGQTATGSGLGLS
HHHHHEECCCCCEEEEEEECEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHH
IVRRIARLHGLQVTFGNAEQGGFEAKVSWKT
HHHHHHHHCCCEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure
MKFTQRLSLRIRLTLIFLILASMTWLVSGFIAWKLTADNVDELFDTQQMLFAKRLIALDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHH
NELRASERIAQTPKKFKHGHIDDDVLAFAVFTRDGKMVMNDGDNGRYIPYSYHREGFDDG
HHHHHHHHHHHCHHHHCCCCCCCHHHEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCC
QLTNDDDSWRFIWLTSADGKYRIVVGQEWEYREEMALGIVLAQLVPWLVALPLMLLILLF
CCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGRELKPLQKIAAALRLRDPESAQPLDTTGVPCEVRPLVDSLNQLFARIHTVMVRERRF
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC
TSDAAHELRSPLTALKVQTEVAQLSVDDPQVRDKALMQLHEGIERATRLVDQLLTLSRLD
CHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLDNLQDVAEISFDDLLQSAVMDIYHTAQQAQIDVRLALNAQGIIRTGQPLLLSLLVRNL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEECCHHHHHHHHHHHH
LDNAVRYSPPGSVVEVTLNTHSFTVKDNGPGVSEEALEHIGERFYRPPGQTATGSGLGLS
HHHHHEECCCCCEEEEEEECEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHH
IVRRIARLHGLQVTFGNAEQGGFEAKVSWKT
HHHHHHHHCCCEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]