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The map label for this gene is qseB [H]

Identifier: 218550275

GI number: 218550275

Start: 3036645

End: 3037304

Strand: Direct

Name: qseB [H]

Synonym: EFER_2967

Alternate gene names: 218550275

Gene position: 3036645-3037304 (Clockwise)

Preceding gene: 218550270

Following gene: 218550276

Centisome position: 66.18

GC content: 52.12

Gene sequence:

>660_bases
ATGCGAATTTTACTTATCGAAGACGATCGTTTGATTGGCGACGGCATTAAAACGGGCTTAAGTAAAATGGGATTCAGTGT
TGACTGGTTTACCGGGGGGCGCGAGGGCAAAGAGGCGCTTTATAGTGCCCCCTATGACGCAATCATTCTTGATCTGACCT
TACCGGGTATAGATGGGCGCGATATTCTGCGGGAGTGGCGGGAAAACGGTAAACGGGAACCAGTACTGATTCTCACCGCT
CGGGATGCGCTGGCTGAGCGGGTTGAAGGTCTGCGTCTGGGAGCTGATGACTATTTATGCAAGCCTTTTGCGCTGATTGA
AGTCGCCGCTCGACTGGAAGCCCTGATCCGTCGAGCCAGCGGCCAGGCCAGCAATGAACTGCACCACGGAAAGGTCATTC
TCGACCCGGGTAAAAGGGTTGCAACGCTTGCAGGCGAACCACTCCCCCTGAAGCCGAAAGAATTTGCCCTGCTGGAACTG
TTGATGCGTAACGTCGGAAGGGTACTGCCACGTAAATTGATTGAAGAAAAACTCTATACCTGGGATGAAGAAGTGACCAG
TAATGCCGTAGAAGTCCATATTCATCACCTGCGGCGTAAACTCGGCAGCGGGTTTATCCGCACTGTTCATGGTATTGGTT
ACACGTTAGGTGAGGCATGA

Upstream 100 bases:

>100_bases
TTAACAACATCTTAAGGGGAAAAAAGAAAATTTTTTGCTGTACAGCTGGCGTTACAAGGCGTTTTACTTGGTGCCATTGA
AGTTTGGTGCGGGAGTAGCG

Downstream 100 bases:

>100_bases
AATTCACACAACGCCTTAGCCTGCGCATCAGGCTGACGCTTATTTTTTTAATTCTGGCTTCCATGACCTGGCTTGTTTCT
GGCTTTATTGCCTGGAAGCT

Product: DNA-binding transcriptional regulator QseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRILLIEDDRLIGDGIKTGLSKMGFSVDWFTGGREGKEALYSAPYDAIILDLTLPGIDGRDILREWRENGKREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALIRRASGQASNELHHGKVILDPGKRVATLAGEPLPLKPKEFALLEL
LMRNVGRVLPRKLIEEKLYTWDEEVTSNAVEVHIHHLRRKLGSGFIRTVHGIGYTLGEA

Sequences:

>Translated_219_residues
MRILLIEDDRLIGDGIKTGLSKMGFSVDWFTGGREGKEALYSAPYDAIILDLTLPGIDGRDILREWRENGKREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALIRRASGQASNELHHGKVILDPGKRVATLAGEPLPLKPKEFALLEL
LMRNVGRVLPRKLIEEKLYTWDEEVTSNAVEVHIHHLRRKLGSGFIRTVHGIGYTLGEA
>Mature_219_residues
MRILLIEDDRLIGDGIKTGLSKMGFSVDWFTGGREGKEALYSAPYDAIILDLTLPGIDGRDILREWRENGKREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALIRRASGQASNELHHGKVILDPGKRVATLAGEPLPLKPKEFALLEL
LMRNVGRVLPRKLIEEKLYTWDEEVTSNAVEVHIHHLRRKLGSGFIRTVHGIGYTLGEA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=91.2844036697248, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=44.4444444444444, Blast_Score=183, Evalue=8e-48,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=39.3665158371041, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=36.8181818181818, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=35.7798165137615, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=35.4545454545455, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=34.5291479820628, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.0649350649351, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.0316742081448, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=30.3964757709251, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=34.0909090909091, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=27.3542600896861, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.7610619469027, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=32.2033898305085, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=32.5, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24436; Mature: 24436

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDRLIGDGIKTGLSKMGFSVDWFTGGREGKEALYSAPYDAIILDLTLPGIDGR
CEEEEEECCCEEHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCEEEEEEECCCCCCH
DILREWRENGKREPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALIRRAS
HHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHC
GQASNELHHGKVILDPGKRVATLAGEPLPLKPKEFALLELLMRNVGRVLPRKLIEEKLYT
CCCCCCCCCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WDEEVTSNAVEVHIHHLRRKLGSGFIRTVHGIGYTLGEA
CCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MRILLIEDDRLIGDGIKTGLSKMGFSVDWFTGGREGKEALYSAPYDAIILDLTLPGIDGR
CEEEEEECCCEEHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCEEEEEEECCCCCCH
DILREWRENGKREPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALIRRAS
HHHHHHHHCCCCCCEEEEECHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHC
GQASNELHHGKVILDPGKRVATLAGEPLPLKPKEFALLELLMRNVGRVLPRKLIEEKLYT
CCCCCCCCCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WDEEVTSNAVEVHIHHLRRKLGSGFIRTVHGIGYTLGEA
CCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]