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The map label for this gene is uxuR [H]

Identifier: 218550264

GI number: 218550264

Start: 3023526

End: 3024314

Strand: Direct

Name: uxuR [H]

Synonym: EFER_2956

Alternate gene names: 218550264

Gene position: 3023526-3024314 (Clockwise)

Preceding gene: 218550262

Following gene: 218550265

Centisome position: 65.89

GC content: 45.37

Gene sequence:

>789_bases
ATGATCGGCTATCCGAGGACACCCACAGTAAGGCTAGGTATGGAACAGGTTATTACAAAGCGCCGCTATTACGATATTGG
TCTACAGATTGAGGAGTTGCTGTATTCAGGCGTATTTAAAGCCGGAGAGCGCCTACCTTCAGAACGTGAACTGAGCGAGC
GGTTTAATACCAGCCGAACTACCATTCGTGAAGCCATCATTATGCTGGAACTGAAAGGCGTGCTGAATGTGAAGCAAGGG
TCAGGGATCTTCTTTGTTGATTCCACCGATAAGCTCAATCAGAAATCCTTGATGCCTTATTCAGAAATTGGCCCGTTTGA
ACTGTTACAGGCACGTCAGGTAATTGAGAGCAATATTACCGGTTTTGCTGCCAGCCAGATCAGCTTTAACGAGTTACAAG
AGTTGAAGAAAATCATTGGATTACAGGAAAAGGCTATCGCTGCGGAAAGCGATAAATTTGAAGAACTGGATCATCGTTTT
CATAGCATTATTGCCGAAGCAACGCAAAATCGGGTACTCATCAAACAAGCCGCTGAATTATGGCGGGCAGTGCGCACAGA
AAACCCCCGCTGGAAGAAACTTAACTACAAGTACCTGCATGAAAAGCATTTGCGTCTGCAATGGCTGGAAGATCACCGGG
CTATTTTCCTGGCTCTGCAACAGAAAGATTCAGAGCTCGCCAGGGAAGCGTCCTGGAGACATCTGGAAAACAGCAAAAAT
GAACTGATCAAAATCTTCAAACAAGACGCTTCCATCAGCGATTTTGATGACTTTTTCTTCGCTCGTTAA

Upstream 100 bases:

>100_bases
TTCACAGCTCAGCCATAGCAAACACATTTAAGGCTAGCGGTATCGTGGCAACTGCCGTTACTATTTATGCCGATCAGCAA
CGCTCAAGTCATGTTGCACG

Downstream 100 bases:

>100_bases
CCTTCATTAGTCCAGAGCTGGCGTGAAAAATGACGCTGGCTCTGCGTTGCACCCTCCACTGGTACACGCTCTCTTCTCAA
TTGGTCTAATAAATCGATTA

Product: regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MIGYPRTPTVRLGMEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRTTIREAIIMLELKGVLNVKQG
SGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVIESNITGFAASQISFNELQELKKIIGLQEKAIAAESDKFEELDHRF
HSIIAEATQNRVLIKQAAELWRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKN
ELIKIFKQDASISDFDDFFFAR

Sequences:

>Translated_262_residues
MIGYPRTPTVRLGMEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRTTIREAIIMLELKGVLNVKQG
SGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVIESNITGFAASQISFNELQELKKIIGLQEKAIAAESDKFEELDHRF
HSIIAEATQNRVLIKQAAELWRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKN
ELIKIFKQDASISDFDDFFFAR
>Mature_262_residues
MIGYPRTPTVRLGMEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRTTIREAIIMLELKGVLNVKQG
SGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVIESNITGFAASQISFNELQELKKIIGLQEKAIAAESDKFEELDHRF
HSIIAEATQNRVLIKQAAELWRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKN
ELIKIFKQDASISDFDDFFFAR

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=247, Percent_Identity=38.4615384615385, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87082208, Length=252, Percent_Identity=38.4920634920635, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786303, Length=220, Percent_Identity=33.1818181818182, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790032, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789353, Length=226, Percent_Identity=27.4336283185841, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 30637; Mature: 30637

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGYPRTPTVRLGMEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRT
CCCCCCCCHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
TIREAIIMLELKGVLNVKQGSGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVIESNIT
HHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHCCCHHHCCHHHHHHHHHHHHHCCC
GFAASQISFNELQELKKIIGLQEKAIAAESDKFEELDHRFHSIIAEATQNRVLIKQAAEL
CHHHCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
WRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKN
HHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCHH
ELIKIFKQDASISDFDDFFFAR
HHHHHHHHCCCCCCHHHHHHCC
>Mature Secondary Structure
MIGYPRTPTVRLGMEQVITKRRYYDIGLQIEELLYSGVFKAGERLPSERELSERFNTSRT
CCCCCCCCHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHH
TIREAIIMLELKGVLNVKQGSGIFFVDSTDKLNQKSLMPYSEIGPFELLQARQVIESNIT
HHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHCCCHHHCCHHHHHHHHHHHHHCCC
GFAASQISFNELQELKKIIGLQEKAIAAESDKFEELDHRFHSIIAEATQNRVLIKQAAEL
CHHHCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
WRAVRTENPRWKKLNYKYLHEKHLRLQWLEDHRAIFLALQQKDSELAREASWRHLENSKN
HHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCHH
ELIKIFKQDASISDFDDFFFAR
HHHHHHHHCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]