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The map label for this gene is nudH [H]

Identifier: 218550078

GI number: 218550078

Start: 2828591

End: 2829121

Strand: Reverse

Name: nudH [H]

Synonym: EFER_2763

Alternate gene names: 218550078

Gene position: 2829121-2828591 (Counterclockwise)

Preceding gene: 218550084

Following gene: 218550077

Centisome position: 61.65

GC content: 50.28

Gene sequence:

>531_bases
GTGATTGATGACGATGGCTACCGCCCAAATGTAGGTATCGTAATTTGTAATCGCCAGGGGCAAGTTATGTGGGCCCGGCG
ATATGGTCAGCACTCCTGGCAATTCCCTCAGGGCGGGATTAACCCAGGAGAATCAGCAGAACAGGCGATGTACCGGGAAC
TGTTTGAAGAGGTTGGATTAAGCCGCAAAGATGTGCGGATCCTCGCCTCGACTCGCAACTGGTTGCGTTACAAGTTACCG
AAACGTTTGGTGCGTTGGGATACAAAGCCGGTGTGTATCGGCCAGAAACAAAAGTGGTTCCTTTTGCAATTGATGAGCGC
TGATGCGGAAATCAATATGCAAACCAGCAGTACTCCAGAGTTTGACGGTTGGCGCTGGGTTAGTTACTGGTACCCCGTCC
GACAGGTGGTGTCATTTAAACGTGATGTCTACCGCAGGGTGATGAAAGAGTTTGCAAGTGTAGTCATGGCGCTTCAGGAC
AATACGCCGAAGCCACAAAACTCACCTGCTTATCGACGTAAAAGAGGTTAA

Upstream 100 bases:

>100_bases
CAAATGTTATTAGTAAGCTGTCGCTTTAACAGAGTGGTTTACCGCCTCACTGGAGTGTGAAACAATCGTTTGTATATAAA
GTTTATGTTGAGGTAGTCCG

Downstream 100 bases:

>100_bases
GTCACGCAAATCATGCTCACTCGCCTGCGCGAAATAGTCGAAAAAGTTGCCAGTGCTCCGCGCCTCAATGAGGCGCTGAA
CATTCTGGTCACCGACATCT

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MIDDDGYRPNVGIVICNRQGQVMWARRYGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQKWFLLQLMSADAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQD
NTPKPQNSPAYRRKRG

Sequences:

>Translated_176_residues
MIDDDGYRPNVGIVICNRQGQVMWARRYGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQKWFLLQLMSADAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQD
NTPKPQNSPAYRRKRG
>Mature_176_residues
MIDDDGYRPNVGIVICNRQGQVMWARRYGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQKWFLLQLMSADAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQD
NTPKPQNSPAYRRKRG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=176, Percent_Identity=96.0227272727273, Blast_Score=355, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20853; Mature: 20853

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDDGYRPNVGIVICNRQGQVMWARRYGQHSWQFPQGGINPGESAEQAMYRELFEEVGL
CCCCCCCCCCCEEEEECCCCCEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLMSADAEINMQTSSTPE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCEEEECCCCCCC
FDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQDNTPKPQNSPAYRRKRG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIDDDGYRPNVGIVICNRQGQVMWARRYGQHSWQFPQGGINPGESAEQAMYRELFEEVGL
CCCCCCCCCCCEEEEECCCCCEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLMSADAEINMQTSSTPE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCEEEECCCCCCC
FDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQDNTPKPQNSPAYRRKRG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA