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The map label for this gene is secD [H]

Identifier: 218549932

GI number: 218549932

Start: 2685755

End: 2687602

Strand: Reverse

Name: secD [H]

Synonym: EFER_2617

Alternate gene names: 218549932

Gene position: 2687602-2685755 (Counterclockwise)

Preceding gene: 218549933

Following gene: 218549931

Centisome position: 58.57

GC content: 52.27

Gene sequence:

>1848_bases
GTGTTAAACCGTTATCCTTTGTGGAAGTACGTCATGCTGATCGTGGTGATTGTCATCGGTCTGCTGTATGCGCTTCCCAA
CCTGTTTGGTGAGGATCCGGCTGTTCAGATCACTGGCGCGCGCGGAGTCGCCGCCAGTGAGCAAACGCTGATCCAGGTCC
AGAAAACGTTACAAGAAGAAAAAATAACTGCTAAGTCTGTGGCACTGGAAGAGGGCGCTATTCTTGCGCGCTTCGACTCC
ACTGACACCCAACTGCGCGCTCGTGAAGCGTTGCTGGATATTCTGGGTGATAAGTACGTCGTGGCGCTTAACCTTGCTCC
GGCAACGCCACGCTGGCTGGCAGCTATTCACGCTGAGCCAATGAAGCTTGGTCTCGATTTGCGTGGCGGCGTTCACTTTC
TGATGGAAGTGGATATGGACACCGCGCTTGGCAAACTCCAGGAACAAAATATCGATAGCCTGCGCAGCGACCTGCGCGAA
AAGGGCATCCCATACACCACCGTTCGTAAAGATAAAAATTACGCACTGACTATCACTTTCCGTGATAGCAAAGCACGTGA
TGAAGCTATCTCTTACTTGTCTCCACGCCATCAGGATTTAGTCATCTCCAGTCAGGGCGATAATGCTCTGCGTGCCGTAA
TGACCGATGCGCGTCTGAGTGAAGCCCGCGAGTATGCGGTGCAGCAGAACATCAATATCCTGCGTAACCGTGTTAACCAA
CTTGGTGTGGCTGAACCGGTGGTACAACGTCAGGGGGCTGACCGCATCGTTGTAGAACTGCCTGGTATCCAGGACACCGC
GCGTGCGAAAGAGATTCTGGGGGCGACGGCAACGCTGGAATTCCGTCTGGTAAACACCAACGTTGATCAGGCCGCTGCTG
CGTCTGGCCGCGTACCGGGTGACTCAGAAGTGAAACAGACTCGCGAAGGTCAGCCGGTAGTGCTGTACAAACGCGTGATT
CTGACCGGTGACCATATTACCGACTCCACTTCAAGCCAGGACGAATACAACCAGCCGCAGGTTAACATCTCGCTCGATAG
CGCAGGTGGTAACATCATGTCTAACTTCACTAAGGACAACATCGGCAAACCGATGGCGACCCTGTTTGTGGAGTACAAAG
ACAGCGGTAAGAAAGATGCAAACGGTCGTGCGGTTCTGGTGAAACAGGAAGAGGTGATAAACATCGCTAACATCCAGTCT
CGTCTGGGTAACAGCTTCCGTATCACTGGTATTAATAACCCGAACGAAGCGCGTCAGCTGTCGCTCCTGCTTCGTGCCGG
TGCGTTGATTGCGCCGATTCAGATTGTTGAAGAACGTACCATTGGCCCGACTCTGGGTATGCAGAACATCGAACAGGGGC
TGGAAGCGTGTCTGGCTGGCCTGCTAGTTTCTATTCTGTTTATGATCCTCTTCTACAAGAAGTTCGGTCTGATTGCGACC
AGTGCTCTGGTTGCTAACTTGATCTTGATTGTCGGCATTATGTCACTGTTGCCTGGTGCAACGCTGAGTATGCCGGGTAT
CGCAGGTATCGTCTTAACCCTTGCGGTGGCAGTCGATGCGAACGTACTGATCAACGAACGTATCAAAGAAGAGTTGAGCA
ACGGACGTTCTGTTCAACAGGCAATTGATGAAGGTTATCGCGGTGCATTCAGTTCCATCTTCGATGCGAACATCACCACG
CTGATTAAAGTCATCATCCTGTACGCAGTGGGTACCGGGGCAATTAAAGGGTTCGCGATTACTACCGGTATCGGTGTGGC
GACGTCGATGTTTACTGCGATTGTCGGTACTCGCGCCATCGTAAACCTGCTATATGGCGGCAAACGCGTCAAGAAGCTGT
CAATCTGA

Upstream 100 bases:

>100_bases
CACCACTGAAGTAGTTATTAAACGTGACTTCGTAGCTGCCGTTCTGCCGAAAGGCACCATGAAGGCGCTGTAATTAAAAT
TTTTCCCTAAGGGAATTGCC

Downstream 100 bases:

>100_bases
GGAGTGCGATGTGGCACAGGAATATACTGTTGAACAACTAAATCATGGCCGTAAAGTCTATGACTTTATGCGCTGGGATT
ACTGGGCTTTCGGCATCTCC

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDS
TDTQLRAREALLDILGDKYVVALNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
KGIPYTTVRKDKNYALTITFRDSKARDEAISYLSPRHQDLVISSQGDNALRAVMTDARLSEAREYAVQQNINILRNRVNQ
LGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVI
LTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQS
RLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMILFYKKFGLIAT
SALVANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRSVQQAIDEGYRGAFSSIFDANITT
LIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI

Sequences:

>Translated_615_residues
MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDS
TDTQLRAREALLDILGDKYVVALNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
KGIPYTTVRKDKNYALTITFRDSKARDEAISYLSPRHQDLVISSQGDNALRAVMTDARLSEAREYAVQQNINILRNRVNQ
LGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVI
LTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQS
RLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMILFYKKFGLIAT
SALVANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRSVQQAIDEGYRGAFSSIFDANITT
LIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI
>Mature_615_residues
MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDS
TDTQLRAREALLDILGDKYVVALNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
KGIPYTTVRKDKNYALTITFRDSKARDEAISYLSPRHQDLVISSQGDNALRAVMTDARLSEAREYAVQQNINILRNRVNQ
LGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVI
LTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQS
RLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMILFYKKFGLIAT
SALVANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRSVQQAIDEGYRGAFSSIFDANITT
LIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=615, Percent_Identity=97.0731707317073, Blast_Score=1207, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 66686; Mature: 66686

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQKTLQEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
KITAKSVALEEGAILARFDSTDTQLRAREALLDILGDKYVVALNLAPATPRWLAAIHAEP
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCH
MKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLREKGIPYTTVRKDKNYALTITF
HHCCCCCCCCEEEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCEEEEEEE
RDSKARDEAISYLSPRHQDLVISSQGDNALRAVMTDARLSEAREYAVQQNINILRNRVNQ
CCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAASGRVPG
CCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEEEEECCCHHHHHCCCCCCC
DSEVKQTREGQPVVLYKRVILTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDN
CHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCCHHC
IGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQSRLGNSFRITGINNPNEARQL
CCCCHHHEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
SLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMILFYKKFGLIAT
HHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALVANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRSVQQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
AIDEGYRGAFSSIFDANITTLIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
VNLLYGGKRVKKLSI
HHHHHCCCCEEECCC
>Mature Secondary Structure
MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQKTLQEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
KITAKSVALEEGAILARFDSTDTQLRAREALLDILGDKYVVALNLAPATPRWLAAIHAEP
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHCCCH
MKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLREKGIPYTTVRKDKNYALTITF
HHCCCCCCCCEEEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCEEEEEEE
RDSKARDEAISYLSPRHQDLVISSQGDNALRAVMTDARLSEAREYAVQQNINILRNRVNQ
CCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAASGRVPG
CCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEEEEECCCHHHHHCCCCCCC
DSEVKQTREGQPVVLYKRVILTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDN
CHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCCHHC
IGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQSRLGNSFRITGINNPNEARQL
CCCCHHHEEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
SLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMILFYKKFGLIAT
HHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALVANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRSVQQ
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
AIDEGYRGAFSSIFDANITTLIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
VNLLYGGKRVKKLSI
HHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]