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The map label for this gene is tolQ [H]

Identifier: 218549690

GI number: 218549690

Start: 2421947

End: 2422639

Strand: Reverse

Name: tolQ [H]

Synonym: EFER_2367

Alternate gene names: 218549690

Gene position: 2422639-2421947 (Counterclockwise)

Preceding gene: 218549691

Following gene: 218549689

Centisome position: 52.8

GC content: 48.63

Gene sequence:

>693_bases
GTGACTGACATGAATATCCTTGATTTGTTCCTGAAGGCTAGCCTTCTGGTTAAACTTATCATGTTGATTTTGATTGGTTT
TTCAATCGCATCCTGGGCCATTATTATCCAGCGGACTCGTATCCTTAACGCAGCGGCGCGCGAAGCCGAAGCGTTTGAAG
ATAAATTCTGGTCTGGAATCGAACTCTCTCGCCTCTACCAGGAGAGCCAGGGAAGGCGTGATAATCTCAGTGGTTCGGAA
CAAATCTTCTACAGTGGGTTCAAAGAGTTTGTTCGTCTCCATAGGGCGAACAGTCATGCTCCTGAAGCTGTTGTTGAAGG
GGCATCGCGTGCTATGCGTATTTCCATGAACCGTGAACTTGAAAACCTGGAAACGCACATTCCGTTCCTCGGCACAGTTG
GCTCCATCAGCCCATATATTGGTCTGTTTGGTACGGTCTGGGGGATTATGCATGCCTTTATCGCCCTTGGTGCAGTAAAA
CAGGCAACGTTACAAATGGTTGCGCCCGGTATCGCAGAAGCGTTGATTGCGACGGCAATCGGTCTGTTTGCCGCTATTCC
GGCAGTTATGGCCTACAACCGTCTCAACCAACGTGTAAACAAACTGGAGCTGAATTACGACAACTTTATGGAAGAGTTTA
CCGCTATTCTGCACCGCCAGGCGTTTACTGTTAGCGAGAGCAACAAGGGGTAA

Upstream 100 bases:

>100_bases
ATACTTTGCTGAATGAAGCAGAGGTTCTGGTTGTTTGCGTTGACCCACTCAAAATGAAGCCTCGTGCGCTTCCCAAGTCT
ATTGTCGCGGAGTTTAAGCA

Downstream 100 bases:

>100_bases
GCCATGGCCAGAGCGCGTGGGCGAGGTCGTCGCGATCTTAAGTCCGAAATCAACATTGTACCGTTGCTGGACGTACTGCT
GGTGCTGCTGCTGATCTTTA

Product: colicin uptake protein TolQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGIELSRLYQESQGRRDNLSGSE
QIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG

Sequences:

>Translated_230_residues
MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGIELSRLYQESQGRRDNLSGSE
QIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG
>Mature_229_residues
TDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGIELSRLYQESQGRRDNLSGSEQ
IFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVKQ
ATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=230, Percent_Identity=99.1304347826087, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1789381, Length=205, Percent_Identity=34.1463414634146, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25612; Mature: 25481

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ELSRLYQESQGRRDNLSGSEQIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNREL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVKQATLQMVAPGIAEALIATAI
HHHHHHCCHHCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ELSRLYQESQGRRDNLSGSEQIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNREL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
ENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVKQATLQMVAPGIAEALIATAI
HHHHHHCCHHCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]