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The map label for this gene is tolR [H]

Identifier: 218549689

GI number: 218549689

Start: 2421515

End: 2421943

Strand: Reverse

Name: tolR [H]

Synonym: EFER_2366

Alternate gene names: 218549689

Gene position: 2421943-2421515 (Counterclockwise)

Preceding gene: 218549690

Following gene: 218549688

Centisome position: 52.78

GC content: 50.12

Gene sequence:

>429_bases
ATGGCCAGAGCGCGTGGGCGAGGTCGTCGCGATCTTAAGTCCGAAATCAACATTGTACCGTTGCTGGACGTACTGCTGGT
GCTGCTGCTGATCTTTATGGCAACGGCCCCCATCATTACCCAGAGCGTGGAAGTCGACTTGCCGGAGGCTACCGACTCGC
AAACAGTGAGTAGTAATGATAATCCACCGGTAATTATTGAAGTTTCTGACGTTGGTCAGTACGCGATATCTGTTGAGAAA
GAGCGACTGGAACGGTTACCTCCTGAGCAGGTAGTGGCAGAAGTTTCAAGCCGATTCAAGGCCAATCCGAAAACGGTCTT
CCTGATCGGTGGTGCGAAAGATGTGCCTTACGATGAAATCATTAAAGCACTGAACTTGTTACACAGTGCGGGTGTGAAAT
CGGTTGGCTTAATGACGCAGCCTATCTAA

Upstream 100 bases:

>100_bases
AAACAAACTGGAGCTGAATTACGACAACTTTATGGAAGAGTTTACCGCTATTCTGCACCGCCAGGCGTTTACTGTTAGCG
AGAGCAACAAGGGGTAAGCC

Downstream 100 bases:

>100_bases
TTACCTGCGTTTCCAGGCGTAAAGATAGCGAGTTACGGGCGAACAGTTTTTGGGAACCAAGAGTGTCAAAGGCAACCGAA
CAAAACGACAAACTTAAACG

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPEATDSQTVSSNDNPPVIIEVSDVGQYAISVEK
ERLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI

Sequences:

>Translated_142_residues
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPEATDSQTVSSNDNPPVIIEVSDVGQYAISVEK
ERLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI
>Mature_141_residues
ARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPEATDSQTVSSNDNPPVIIEVSDVGQYAISVEKE
RLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). [C]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=132, Percent_Identity=92.4242424242424, Blast_Score=219, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15457; Mature: 15326

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPEATDSQTVSSND
CCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
NPPVIIEVSDVGQYAISVEKERLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEI
CCCEEEEECCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
IKALNLLHSAGVKSVGLMTQPI
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPEATDSQTVSSND
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
NPPVIIEVSDVGQYAISVEKERLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEI
CCCEEEEECCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
IKALNLLHSAGVKSVGLMTQPI
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]