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The map label for this gene is fiu [H]

Identifier: 218549628

GI number: 218549628

Start: 2360764

End: 2363046

Strand: Direct

Name: fiu [H]

Synonym: EFER_2303

Alternate gene names: 218549628

Gene position: 2360764-2363046 (Clockwise)

Preceding gene: 218549627

Following gene: 218549629

Centisome position: 51.45

GC content: 53.44

Gene sequence:

>2283_bases
ATGGAAAACAATCGCAATTTCCCTGCCAGACAATTTCATTCGCTCACGTTCTTTGCCGGTCTTTGTATTGGTATTACGCC
TGTGGCACAGGCACTCGCCGCCGAAGGGCAAACTAACGCGGATGACACGCTGGTTGTCGAAGCATCAACGCCTTCGCTTT
ATGCACCACAACAATCTGCCGATCCGAAATTCTCGCGTCCGGTAGCGGATACGACCCGCACGATGACGGTGATTTCTGAA
CAAGTGATTAAAGATCAGGGCGCAACCAACCTTACCGATGCGCTCAAAAACGTCCCCGGAGTGGGTGCGTTTTTTGCTGG
TGAGAACGGTAACTCCACCACTGGCGACGCCATTTATATGCGCGGTGCCGATACTTCTAACAGTATTTATATTGATGGCA
TTCGCGATATCGGCAGCGTCTCACGCGACACCTTCAATACCGAACAGGTCGAAGTGATTAAAGGGCCGTCCGGCACCGAC
TACGGGCGCAGCGCGCCGACGGGCTCGATCAATATGATCAGCAAGCAGCCGCGCAATGATTCAGGCATTGACGCTTCCGC
CAGTATTGGCAGCGCCTGGTTCCGCCGCGGCACGCTGGACGTCAATCAGGTCATTGGTGATACCACCGCGGTGCGCCTGA
ATGTGATGGGTGAAAAAACGCACGATGCCGGACGCGACAAAGTTAAAAATGAGCGTTACGGCGTCGCCCCTTCTGTAGCT
TTTGGCCTTGGCACAGCGAATCGTTTGTATCTTAATTATCTGCATGTCACCCAGCACAACACGCCAGACGGCGGCATTCC
GACCATCGGTTTGCCGGGCTATTCTGCCCCATCTGCGGGAACGGCGGCCCTGAATCATTCCGGAAAAGTTGATACGCATA
ACTTTTACGGCACGGATTCCGATTACGACGATTCGACCACCGACACCGCTACCATGCGTTTTGAGCACGACATCAACGAT
AACACCACCATTCGCAATACTACCCGTTGGTCGCGCGTAAAGCAGGATTACCTGATGACGGCGATTATGGGCGGGGCATC
GAATATTACCCAGCCCACCAGCGATGTGAATAGCTGGACGTGGTCACGTACGGCGAATACCAAGGATGTGAGTAATAAAA
TTCTCACCAACCAGACCAACCTGACCTCGACGTTCTATACCGGTTCTATCGGTCATGATGTCAGTACTGGCGTGGAATTT
ACCCGTGAAACGCAGACTAACTATGGCGTTAATCCGGTCACGTTACCTGCGGTGAATATTTATCATCCTGACAGCAGCAT
TCATCCTGGCGGCCTGACGCGTAACGGCGCAAACGCCAATGGTCAGACGGATACCTTCGCAATTTATGCCTTCGATACGC
TGCAAATCACCCGTGATTTTGAGCTGAACGGCGGGATCCGTCTGGATAATTATCATACTGAATATGACAGTGCCACCGCC
TGCGGCGGCAGTGGCCGAGGTGCCGTTACCTGCCCAGCTGGCGTGGCGAAAGGTTCTCCGGTCACCACTGTTGACACCGC
CAAGTCTGGCAATCTGGTGAACTGGAAAGCCGGGGCGCTGTATCACCTGACGGAAAACGGCAATGTCTATATTAACTATG
CCGTTTCCCAACAGCCGCCGGGCGGCAACAACTTCGCCCTTGCGCAGTCTGGCAGCGGTAACAGTGCCAACCGTACCGAT
TTTAAACCGCAAAAAGCCAACACCAGCGAGATTGGCACCAAATGGCAGGTTCTGGATAAACGCCTGTTGCTCACCGCCGC
GCTGTTCCGTACTGATATCGAAAATGAAGTTGAGCAAAATGACGACGGGACTTACTCGCAATACGGTAAGAAACGCGTCG
AAGGCTATGAGATATCCGTAGCCGGGAATATCACTCCCGCGTGGCAGGTGATTGGCGGCTATACCCAGCAAAAAGCAACC
ATCAAAAACGGCAAAGATGTTGCCCAGGATGGTTCCTCATCGCTGCCGTATACCCCGGAGCACGCCTTTACCTTATGGAG
CCAGTATCAGGCAACCGATGATATCTCTGTTGGCGCGGGCGCTCGCTATATCGGCAGTATGCATAAAGGTTCAGACGGCG
CGGTGGGAACGCCAGCATTTACCGAGGGTTATTGGGTCGCCGATGCCAAACTGGGGTATCGGGTTAATCGCAATCTCGAC
TTCCAGCTAAACGTCTACAACCTGTTTGATACCGATTACGTCGCCTCAATCAACAAGAGCGGCTACCGTTATCACCCGGG
CGAGCCAAGAACCTTCCTGCTCACGGCCAATATGCATTTCTGA

Upstream 100 bases:

>100_bases
GCACGAACGCTATCACGGGATTAACAGTGGCATCGCATCCGCAGAGATGCTTTCTCGTGACAGTGAAAATTTCAACATAT
AAGAAAAAGTCACCTGCAAA

Downstream 100 bases:

>100_bases
TTCAGATGTGGGGCGCAGGCCCCACTTTTTGGAGAACTTGTATGATGTACCACATTCCCGGCGTGCTATCGCCAAAGGAC
GTCGCCCGGTTTCGCGAACA

Product: catecholate siderophore receptor Fiu

Products: NA

Alternate protein names: Ferric iron uptake protein; TonB-dependent receptor fiu [H]

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAVTCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF

Sequences:

>Translated_760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAVTCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
>Mature_760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAVTCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF

Specific function: Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein

COG id: COG4774

COG function: function code P; Outer membrane receptor for monomeric catechols

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=760, Percent_Identity=99.6052631578947, Blast_Score=1559, Evalue=0.0,
Organism=Escherichia coli, GI1786344, Length=818, Percent_Identity=24.6943765281174, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1790405, Length=207, Percent_Identity=29.951690821256, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787723, Length=256, Percent_Identity=28.515625, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81885; Mature: 81885

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCC
DPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYM
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCEEEE
RGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTDYGRSAPTGSINMISKQPRND
ECCCCCCCEEEECCHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
SGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
CCCCCCCCCCHHHHHCCCCCHHHHHCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHE
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDS
ECCCCCCEEEEEEEEEEECCCCCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
DYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWT
CCCCCCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
WSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEFTRETQTNYGVNPVTLPAVNI
EECCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEE
YHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCCCEEECCCCCCCCCCCC
CGGSGRGAVTCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPP
CCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEECCEEEEEECCCCEEEEEEECCCCC
GGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQN
CCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPE
CCCCHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCEECCCCCHHHCCCCCCCCCCCC
HAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
HHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECEECEEECCCEE
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
EEEEEEEECCCCHHHHCCCCCCEECCCCCEEEEEEECCCC
>Mature Secondary Structure
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCC
DPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYM
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCEEEE
RGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTDYGRSAPTGSINMISKQPRND
ECCCCCCCEEEECCHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
SGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
CCCCCCCCCCHHHHHCCCCCHHHHHCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHE
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDS
ECCCCCCEEEEEEEEEEECCCCCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
DYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWT
CCCCCCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
WSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEFTRETQTNYGVNPVTLPAVNI
EECCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEE
YHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCCCEEECCCCCCCCCCCC
CGGSGRGAVTCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPP
CCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEECCEEEEEECCCCEEEEEEECCCCC
GGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQN
CCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPE
CCCCHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCEECCCCCHHHCCCCCCCCCCCC
HAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
HHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECEECEEECCCEE
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
EEEEEEEECCCCHHHHCCCCCCEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]