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The map label for this gene is rbtR [H]

Identifier: 218549507

GI number: 218549507

Start: 2218322

End: 2219353

Strand: Reverse

Name: rbtR [H]

Synonym: EFER_2178

Alternate gene names: 218549507

Gene position: 2219353-2218322 (Counterclockwise)

Preceding gene: 218549511

Following gene: 218549505

Centisome position: 48.37

GC content: 50.19

Gene sequence:

>1032_bases
GTGACACGCGTTGAGAAAACGAAGAAAACGACCATTTACGACCTGGCAGAATTAACCGGCGTTTCTGCCAGTGCGGTAAG
CGCTATTTTGAATGGCAACTGGAAAAAGCGACGCATCAGCGCAAAGCTGGCTGAGAAGGTCACCCGTATTGCAGAAGAGC
AAGGCTATGCCGTTAATCGGCAGGCAAGTTTACTGCGCAGTAAAAAATCCAACGTTATTGGCATGATTGTGCCGAAATAC
GACAACCGATACTTTGGATCGATTGCCGAAAAATTTGAAGAGATGGCGCGAGCCAGAGGATTACTGCCAATCATCACCTG
TACGCGGCGACAACCCGAACTGGAAATTGAGGCTGCTCGCGCCATGCTCTCCTGGCAGGTGGATTGGGTCATTGCTACCG
GAGCGACTCAACCGGATAAAATAGCCAAAATGTGTCAGCAAGCGGGCGTACCGACACTGAATCTGGATCTGCCGGGAACA
CTGGCGCCGTCGATCATTTCTGATAACTACATGGGGGCGAAATTATTGACGGAAAGAATTTTAGCCAACAGCCAGAAACG
CTATGGCAAGTTGGCGCCTTTAATTTTTGTCGGCGGACGTATCAGCGATAACAATACCGCTGAGCGTTTACGTGGTTTTG
TCGATGCCCATCAGGCTTTGGGGATAACCGTACCGGATGAATATAAACTGGTTACCGGCTACTCTTCTGCTCGTGTAGAG
GGATTACTGAAAGAGGTTTTCCAAAGCTCTTCAGTGTCGCTTCACGGGTTATTCGTCAACTCGACAATCTCTCTTGAAGG
GGTGGTGCGCTGGCTGGCACAAACCGGGCAGACGGGAGCCAATCAACCGCCAATGGGATGTTTTGACTGGGATCCTTTTG
TTTCTCTGCTCGGGCACGATATCGATATGGTTCGTCAGGATGTACCCGCCATGCTCGAAAAAGTGTTTGAAATTGTGGAT
TCTGGCGATACCACCCTGCGTCGCATTGAGATACCGCCACAACTCATTCCCAGCCTGAATGTTGTCAGCTGA

Upstream 100 bases:

>100_bases
AATTTAGCTGGCGTGTGAAGCAAACTGCTCAATCGATGAAGCAGATCTAGCACTTGCTTAAATTCTCAGCAAGAGACATT
CAAAATGAAGAGGCAAATTT

Downstream 100 bases:

>100_bases
GATTAACGTGTCAGCAACCAGCGTGCGGTGTGTTCATCGGTAACCAGACCGTTGATCCACCCACCTTTTAATGCCGCGAG
GATCGCCGGACGTTTATCCT

Product: catabolite repressor protein

Products: NA

Alternate protein names: Rbt operon repressor [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTRVEKTKKTTIYDLAELTGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAVNRQASLLRSKKSNVIGMIVPKY
DNRYFGSIAEKFEEMARARGLLPIITCTRRQPELEIEAARAMLSWQVDWVIATGATQPDKIAKMCQQAGVPTLNLDLPGT
LAPSIISDNYMGAKLLTERILANSQKRYGKLAPLIFVGGRISDNNTAERLRGFVDAHQALGITVPDEYKLVTGYSSARVE
GLLKEVFQSSSVSLHGLFVNSTISLEGVVRWLAQTGQTGANQPPMGCFDWDPFVSLLGHDIDMVRQDVPAMLEKVFEIVD
SGDTTLRRIEIPPQLIPSLNVVS

Sequences:

>Translated_343_residues
MTRVEKTKKTTIYDLAELTGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAVNRQASLLRSKKSNVIGMIVPKY
DNRYFGSIAEKFEEMARARGLLPIITCTRRQPELEIEAARAMLSWQVDWVIATGATQPDKIAKMCQQAGVPTLNLDLPGT
LAPSIISDNYMGAKLLTERILANSQKRYGKLAPLIFVGGRISDNNTAERLRGFVDAHQALGITVPDEYKLVTGYSSARVE
GLLKEVFQSSSVSLHGLFVNSTISLEGVVRWLAQTGQTGANQPPMGCFDWDPFVSLLGHDIDMVRQDVPAMLEKVFEIVD
SGDTTLRRIEIPPQLIPSLNVVS
>Mature_342_residues
TRVEKTKKTTIYDLAELTGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAVNRQASLLRSKKSNVIGMIVPKYD
NRYFGSIAEKFEEMARARGLLPIITCTRRQPELEIEAARAMLSWQVDWVIATGATQPDKIAKMCQQAGVPTLNLDLPGTL
APSIISDNYMGAKLLTERILANSQKRYGKLAPLIFVGGRISDNNTAERLRGFVDAHQALGITVPDEYKLVTGYSSARVEG
LLKEVFQSSSVSLHGLFVNSTISLEGVVRWLAQTGQTGANQPPMGCFDWDPFVSLLGHDIDMVRQDVPAMLEKVFEIVDS
GDTTLRRIEIPPQLIPSLNVVS

Specific function: Repressor for the genes of the ribitol operon. Binds D- ribulose as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787906, Length=352, Percent_Identity=26.1363636363636, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994940, Length=239, Percent_Identity=27.1966527196653, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786268, Length=127, Percent_Identity=33.8582677165354, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789202, Length=224, Percent_Identity=28.125, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788474, Length=184, Percent_Identity=26.6304347826087, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790194, Length=227, Percent_Identity=25.9911894273128, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37777; Mature: 37646

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVEKTKKTTIYDLAELTGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAVNR
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECH
QASLLRSKKSNVIGMIVPKYDNRYFGSIAEKFEEMARARGLLPIITCTRRQPELEIEAAR
HHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
AMLSWQVDWVIATGATQPDKIAKMCQQAGVPTLNLDLPGTLAPSIISDNYMGAKLLTERI
HHHHEEEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCHHHHHHHHH
LANSQKRYGKLAPLIFVGGRISDNNTAERLRGFVDAHQALGITVPDEYKLVTGYSSARVE
HHCCHHHHCCCCCEEEECCEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHH
GLLKEVFQSSSVSLHGLFVNSTISLEGVVRWLAQTGQTGANQPPMGCFDWDPFVSLLGHD
HHHHHHHCCCCCEEEEEEEECEECHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCC
IDMVRQDVPAMLEKVFEIVDSGDTTLRRIEIPPQLIPSLNVVS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCC
>Mature Secondary Structure 
TRVEKTKKTTIYDLAELTGVSASAVSAILNGNWKKRRISAKLAEKVTRIAEEQGYAVNR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECH
QASLLRSKKSNVIGMIVPKYDNRYFGSIAEKFEEMARARGLLPIITCTRRQPELEIEAAR
HHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHH
AMLSWQVDWVIATGATQPDKIAKMCQQAGVPTLNLDLPGTLAPSIISDNYMGAKLLTERI
HHHHEEEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCHHHHHHHHH
LANSQKRYGKLAPLIFVGGRISDNNTAERLRGFVDAHQALGITVPDEYKLVTGYSSARVE
HHCCHHHHCCCCCEEEECCEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHH
GLLKEVFQSSSVSLHGLFVNSTISLEGVVRWLAQTGQTGANQPPMGCFDWDPFVSLLGHD
HHHHHHHCCCCCEEEEEEEECEECHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCC
IDMVRQDVPAMLEKVFEIVDSGDTTLRRIEIPPQLIPSLNVVS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3891331 [H]