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The map label for this gene is dalD [H]

Identifier: 218549505

GI number: 218549505

Start: 2215798

End: 2217210

Strand: Reverse

Name: dalD [H]

Synonym: EFER_2176

Alternate gene names: 218549505

Gene position: 2217210-2215798 (Counterclockwise)

Preceding gene: 218549507

Following gene: 218549504

Centisome position: 48.32

GC content: 49.89

Gene sequence:

>1413_bases
ATGTTCGATTACAGTTCAGCCATAACGTCAATGGAGAACGAAACAATGAACGAACAATTTACATGGCTGCACATCGGGTT
AGGTTCTTTTCATCGCGCGCATCAGGCGTGGTATCTACACCGTTTGCATGTGATGGGCGATAAACGCTGGAGCATTGCTG
CGGGAAATATTCGTAACGATGCTGAACATGTCGTACAGGCACTCAGTGCGCAGAAAGGTCGCTATGTGCTGGAAACCGTT
AGCCCGGAAGGGGTAAGCGAATATGAAGAGATCACCTCAATTCAGAAGCTGATACCGTGGCAGGCAGATTTACAACCGCT
GATTGCTGAAGGGGCAGATCCGAAGACAAAAGTGATTGCTTTCACCGTCACCGAAGGCGGGTACTACCTGAACACCAGTC
ACAAACTGGAAGTCAACAATCCTGATTTAGCGGCAGATCTTAAAGGGGGATGCAAAACAATTTACGGTGTTATTACCCGT
ATCCTCGAAGCGCGTATGGCAAATAACGCCGGACCTCTGACCCTGCTGAATTGCGATAACGTGCGCCATAATGGTGAACG
TTTCCATGATGGTCTGGTCGAGTTTCTCCAGCTGACTGGCAAACAGGATGTCATCGACTGGCTGAGTACAAATACTACTT
GCCCGAACACCATGGTTGACCGCATTACGCCTCGTCCGGCAGCAGAACTTCCGGCACGGATCAAGGCACAAACAGGTATT
GCAGATAAAGCGCCGGTAATGGGTGAAACCTTTATCCAGTGGGTCGTGGAGGATAATTTCCGCGATGTGCGCCCGGCACT
GGAGAAGGTCGGTGTTGAGCTGGTGGCGTCGGTAATCCCCTATGAAGAGGCGAAGATTCGCATTCTTAACTCTTCACACA
GTTGCATCGCCTGGGCAGGTACGTTAATCGGTCAAAAATATATCCACGAAAGCACAATGACCGATTTTATCTATCAGATT
GCCGACCGCTACGTGACGGAAGATGTCATTCCTTGTCTGGGCGATAACGGTATCGATTTGCCAACCTACCGTGATGTTGT
ACTCAAGCGTTTTACCAATCCACATATTCAGGACACCAACCAACGTGTCGCTGCGGATGGTTTCTCGAAAATTCCGGCGA
TGATTGCCCCCACACTGCGAGAGTGCTACCAGCGAGGCGTTCGCCCGAATGCCACAGCCATGTTACCTGCTCTGTTTTAC
GTATTCATGGAGCAGTGGCATCACGGCAAACTGCCCTATGAATATCAGGATGGCATCCTCGATGCGCCAGCTGTTCATGC
AATGTTCCAGTCTGCCGATCCCGTCGCTGTTTATGCCAGTGATAAAGCGCTGTTTGGCGATTTAACCGAACGTGAAGATT
TTGCCGCGTTGTTGCGCGAAAAAATCGCTGACGTCTACGCGTTAATTAACTAA

Upstream 100 bases:

>100_bases
GATAGCTTTACCGCGAGGCAAGTTTATTGCTTTGATTTGGTCATTTGTAATTTTTACGGTCAATTGTTCTTTTGTGATCT
AACGCTCTTAATTAACTCAA

Downstream 100 bases:

>100_bases
CCAGGAGGCGGTTATGTATCTGGGTATCGATCTGGGCACATCGGAAGTTAAGGCGCTGGTCATTGATGAAAACAATGAAA
TTGTTGCCACCCATAGTGCG

Product: D-arabinitol 4-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MFDYSSAITSMENETMNEQFTWLHIGLGSFHRAHQAWYLHRLHVMGDKRWSIAAGNIRNDAEHVVQALSAQKGRYVLETV
SPEGVSEYEEITSIQKLIPWQADLQPLIAEGADPKTKVIAFTVTEGGYYLNTSHKLEVNNPDLAADLKGGCKTIYGVITR
ILEARMANNAGPLTLLNCDNVRHNGERFHDGLVEFLQLTGKQDVIDWLSTNTTCPNTMVDRITPRPAAELPARIKAQTGI
ADKAPVMGETFIQWVVEDNFRDVRPALEKVGVELVASVIPYEEAKIRILNSSHSCIAWAGTLIGQKYIHESTMTDFIYQI
ADRYVTEDVIPCLGDNGIDLPTYRDVVLKRFTNPHIQDTNQRVAADGFSKIPAMIAPTLRECYQRGVRPNATAMLPALFY
VFMEQWHHGKLPYEYQDGILDAPAVHAMFQSADPVAVYASDKALFGDLTEREDFAALLREKIADVYALIN

Sequences:

>Translated_470_residues
MFDYSSAITSMENETMNEQFTWLHIGLGSFHRAHQAWYLHRLHVMGDKRWSIAAGNIRNDAEHVVQALSAQKGRYVLETV
SPEGVSEYEEITSIQKLIPWQADLQPLIAEGADPKTKVIAFTVTEGGYYLNTSHKLEVNNPDLAADLKGGCKTIYGVITR
ILEARMANNAGPLTLLNCDNVRHNGERFHDGLVEFLQLTGKQDVIDWLSTNTTCPNTMVDRITPRPAAELPARIKAQTGI
ADKAPVMGETFIQWVVEDNFRDVRPALEKVGVELVASVIPYEEAKIRILNSSHSCIAWAGTLIGQKYIHESTMTDFIYQI
ADRYVTEDVIPCLGDNGIDLPTYRDVVLKRFTNPHIQDTNQRVAADGFSKIPAMIAPTLRECYQRGVRPNATAMLPALFY
VFMEQWHHGKLPYEYQDGILDAPAVHAMFQSADPVAVYASDKALFGDLTEREDFAALLREKIADVYALIN
>Mature_470_residues
MFDYSSAITSMENETMNEQFTWLHIGLGSFHRAHQAWYLHRLHVMGDKRWSIAAGNIRNDAEHVVQALSAQKGRYVLETV
SPEGVSEYEEITSIQKLIPWQADLQPLIAEGADPKTKVIAFTVTEGGYYLNTSHKLEVNNPDLAADLKGGCKTIYGVITR
ILEARMANNAGPLTLLNCDNVRHNGERFHDGLVEFLQLTGKQDVIDWLSTNTTCPNTMVDRITPRPAAELPARIKAQTGI
ADKAPVMGETFIQWVVEDNFRDVRPALEKVGVELVASVIPYEEAKIRILNSSHSCIAWAGTLIGQKYIHESTMTDFIYQI
ADRYVTEDVIPCLGDNGIDLPTYRDVVLKRFTNPHIQDTNQRVAADGFSKIPAMIAPTLRECYQRGVRPNATAMLPALFY
VFMEQWHHGKLPYEYQDGILDAPAVHAMFQSADPVAVYASDKALFGDLTEREDFAALLREKIADVYALIN

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790779, Length=443, Percent_Identity=31.8284424379233, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1787823, Length=447, Percent_Identity=30.8724832214765, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1788497, Length=362, Percent_Identity=29.5580110497238, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI48994885, Length=388, Percent_Identity=23.4536082474227, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790028, Length=219, Percent_Identity=25.1141552511416, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324401, Length=455, Percent_Identity=32.0879120879121, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6320765, Length=455, Percent_Identity=32.0879120879121, Blast_Score=225, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.11 [H]

Molecular weight: Translated: 52669; Mature: 52669

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDYSSAITSMENETMNEQFTWLHIGLGSFHRAHQAWYLHRLHVMGDKRWSIAAGNIRND
CCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
AEHVVQALSAQKGRYVLETVSPEGVSEYEEITSIQKLIPWQADLQPLIAEGADPKTKVIA
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEE
FTVTEGGYYLNTSHKLEVNNPDLAADLKGGCKTIYGVITRILEARMANNAGPLTLLNCDN
EEEECCCEEECCCCEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
VRHNGERFHDGLVEFLQLTGKQDVIDWLSTNTTCPNTMVDRITPRPAAELPARIKAQTGI
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCCCCHHHCCCHHHHHCCC
ADKAPVMGETFIQWVVEDNFRDVRPALEKVGVELVASVIPYEEAKIRILNSSHSCIAWAG
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
TLIGQKYIHESTMTDFIYQIADRYVTEDVIPCLGDNGIDLPTYRDVVLKRFTNPHIQDTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCC
QRVAADGFSKIPAMIAPTLRECYQRGVRPNATAMLPALFYVFMEQWHHGKLPYEYQDGIL
CHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCC
DAPAVHAMFQSADPVAVYASDKALFGDLTEREDFAALLREKIADVYALIN
CCHHHHHHHCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFDYSSAITSMENETMNEQFTWLHIGLGSFHRAHQAWYLHRLHVMGDKRWSIAAGNIRND
CCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
AEHVVQALSAQKGRYVLETVSPEGVSEYEEITSIQKLIPWQADLQPLIAEGADPKTKVIA
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCEEEE
FTVTEGGYYLNTSHKLEVNNPDLAADLKGGCKTIYGVITRILEARMANNAGPLTLLNCDN
EEEECCCEEECCCCEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
VRHNGERFHDGLVEFLQLTGKQDVIDWLSTNTTCPNTMVDRITPRPAAELPARIKAQTGI
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCCCCHHHCCCHHHHHCCC
ADKAPVMGETFIQWVVEDNFRDVRPALEKVGVELVASVIPYEEAKIRILNSSHSCIAWAG
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHH
TLIGQKYIHESTMTDFIYQIADRYVTEDVIPCLGDNGIDLPTYRDVVLKRFTNPHIQDTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCC
QRVAADGFSKIPAMIAPTLRECYQRGVRPNATAMLPALFYVFMEQWHHGKLPYEYQDGIL
CHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCC
DAPAVHAMFQSADPVAVYASDKALFGDLTEREDFAALLREKIADVYALIN
CCHHHHHHHCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9639934 [H]