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The map label for this gene is xylB [H]

Identifier: 218549504

GI number: 218549504

Start: 2214321

End: 2215784

Strand: Reverse

Name: xylB [H]

Synonym: EFER_2175

Alternate gene names: 218549504

Gene position: 2215784-2214321 (Counterclockwise)

Preceding gene: 218549505

Following gene: 218549503

Centisome position: 48.29

GC content: 54.44

Gene sequence:

>1464_bases
ATGTATCTGGGTATCGATCTGGGCACATCGGAAGTTAAGGCGCTGGTCATTGATGAAAACAATGAAATTGTTGCCACCCA
TAGTGCGCCGCTGACCATTCAGCGCCCCCATCCACACTGGTCAGAACAATCGCCGCAAGCCTGGTGGGAAGCGACGGAAT
ATTTAATGACGACCCTGCGGGAAAAATGCGGTCACCACTGGCAGGCGATCAAGGCCATTGGCCTTTCTGGTCAAATGCAT
GGTGCCGTCCTGCTGGATGAAAAAGGAGAGGCGATTCGTCCGGCGATTTTATGGAACGACACCCGCAGTGCGCAGGAGTG
CGCGGAGCTGGAAGAGATTGCACCAGAGTTGCATCAGGTAGCGGGAAACCTGGCGATGCCTGGATTTACCGCCCCCAAAT
TGCTATGGGTACGGCGCCATGAGCCGCAGCACTTTGCGCGCATTTCCACCGTTTTACTGCCGAAAGACTATTTGCGTTTC
AAAATGACCGGCCAAAAGATTTCCGATATGTCGGATTCTGCTGGCACGTTGTGGCTTGATGTTGAAAAACGCGACTGGTC
AGATTCGTTACTGGAAAAATGTGGCCTGACACGGGCGAATATGCCGGAACTGGTAGAAGGTTGTGACGTTTCTGCCACTC
TTTCCCCTGAAGTTGCCAGCCGATGGGGGCTGACATCTTCGGTTGTTGTTGCTGGCGGCGGTGGCGATAACGCCGTGAGT
GCAATTGGTGTGGGGGCCGTTTCTCCCGGAGATGCGTTTATTTCTTTGGGAACTTCCGGGGTGTTGTTTGTGGTGACAGA
TGCCTATCGTCCTGCGCCGCAATCAGCAGTCCATGCTTTCTGTCACGTACTACCGAATTTATGGCACCAGATGAGTGTCA
TGCTCAGTGCCGCCAGTTGCCTGCAATGGTTCTGCCGCCTGGTGGGGGTAACGGAAACAGAGCTACTGGAAGAGATTGCC
CAACTTTCTGATGCAGACAAAGCCAGCGCACCGATGTTCCTCCCGTATCTTTCTGGTGAACGTACGCCACATAACGATCC
TCATGCCCGGGGAATGTTCTGGGGGCTGACACACTCCAGTCAGCGTGCGCTAATGGGATATGCAGTGCTGGAAGGTGTCA
GCTTTGGTATTGCCGATGGGCTGCGAGTCCTGCAAGAAAGCGGTACGGCAATTGAGCAATGCTCGCTGGTAGGTGGGGGG
GCGAGAAGTCCATTCTGGGCGCAGTTACTGGCCGACATTCTCGATATGCCAGTGGTGACGCATAAAGGCGGTGAGACGGG
GGGGGCGCTGGGAGCCGCGCGTCTGGCCTGTCTGGCTACGGGAAAACCACTGGCGGCAGTGTGTGAAAAACCTGAAATCT
TCAAAACCTGGCGCAGCGATCCTGAACGTCATAAAGCGCTGATGCAACGATATCAGCAGTTTACTGCGCTGTACCACAAC
GACCTGAACTATCGCAATCAATAA

Upstream 100 bases:

>100_bases
GCGCTGTTTGGCGATTTAACCGAACGTGAAGATTTTGCCGCGTTGTTGCGCGAAAAAATCGCTGACGTCTACGCGTTAAT
TAACTAACCAGGAGGCGGTT

Downstream 100 bases:

>100_bases
CATCTGTCACAAATGCCCTCCGGTGTGTGCACCGGAGCGGCGTTTTGTATCCTACAAACGAGGTCACTATGTCGTTAACA
AATAAACAATGGCTGGGATT

Product: Xylulose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MYLGIDLGTSEVKALVIDENNEIVATHSAPLTIQRPHPHWSEQSPQAWWEATEYLMTTLREKCGHHWQAIKAIGLSGQMH
GAVLLDEKGEAIRPAILWNDTRSAQECAELEEIAPELHQVAGNLAMPGFTAPKLLWVRRHEPQHFARISTVLLPKDYLRF
KMTGQKISDMSDSAGTLWLDVEKRDWSDSLLEKCGLTRANMPELVEGCDVSATLSPEVASRWGLTSSVVVAGGGGDNAVS
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASCLQWFCRLVGVTETELLEEIA
QLSDADKASAPMFLPYLSGERTPHNDPHARGMFWGLTHSSQRALMGYAVLEGVSFGIADGLRVLQESGTAIEQCSLVGGG
ARSPFWAQLLADILDMPVVTHKGGETGGALGAARLACLATGKPLAAVCEKPEIFKTWRSDPERHKALMQRYQQFTALYHN
DLNYRNQ

Sequences:

>Translated_487_residues
MYLGIDLGTSEVKALVIDENNEIVATHSAPLTIQRPHPHWSEQSPQAWWEATEYLMTTLREKCGHHWQAIKAIGLSGQMH
GAVLLDEKGEAIRPAILWNDTRSAQECAELEEIAPELHQVAGNLAMPGFTAPKLLWVRRHEPQHFARISTVLLPKDYLRF
KMTGQKISDMSDSAGTLWLDVEKRDWSDSLLEKCGLTRANMPELVEGCDVSATLSPEVASRWGLTSSVVVAGGGGDNAVS
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASCLQWFCRLVGVTETELLEEIA
QLSDADKASAPMFLPYLSGERTPHNDPHARGMFWGLTHSSQRALMGYAVLEGVSFGIADGLRVLQESGTAIEQCSLVGGG
ARSPFWAQLLADILDMPVVTHKGGETGGALGAARLACLATGKPLAAVCEKPEIFKTWRSDPERHKALMQRYQQFTALYHN
DLNYRNQ
>Mature_487_residues
MYLGIDLGTSEVKALVIDENNEIVATHSAPLTIQRPHPHWSEQSPQAWWEATEYLMTTLREKCGHHWQAIKAIGLSGQMH
GAVLLDEKGEAIRPAILWNDTRSAQECAELEEIAPELHQVAGNLAMPGFTAPKLLWVRRHEPQHFARISTVLLPKDYLRF
KMTGQKISDMSDSAGTLWLDVEKRDWSDSLLEKCGLTRANMPELVEGCDVSATLSPEVASRWGLTSSVVVAGGGGDNAVS
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASCLQWFCRLVGVTETELLEEIA
QLSDADKASAPMFLPYLSGERTPHNDPHARGMFWGLTHSSQRALMGYAVLEGVSFGIADGLRVLQESGTAIEQCSLVGGG
ARSPFWAQLLADILDMPVVTHKGGETGGALGAARLACLATGKPLAAVCEKPEIFKTWRSDPERHKALMQRYQQFTALYHN
DLNYRNQ

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=448, Percent_Identity=23.2142857142857, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI189409120, Length=451, Percent_Identity=23.2815964523282, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4504007, Length=448, Percent_Identity=23.2142857142857, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI164663828, Length=543, Percent_Identity=23.3885819521179, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI41393575, Length=442, Percent_Identity=22.3981900452489, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI164663830, Length=280, Percent_Identity=24.6428571428571, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI18860918, Length=463, Percent_Identity=20.3023758099352, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1789987, Length=485, Percent_Identity=51.7525773195876, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1790005, Length=483, Percent_Identity=24.8447204968944, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1787789, Length=509, Percent_Identity=25.3438113948919, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790361, Length=482, Percent_Identity=24.6887966804979, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789168, Length=455, Percent_Identity=25.7142857142857, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786249, Length=486, Percent_Identity=22.4279835390947, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17535599, Length=445, Percent_Identity=25.6179775280899, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17554530, Length=531, Percent_Identity=22.0338983050847, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321633, Length=339, Percent_Identity=27.7286135693215, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320314, Length=567, Percent_Identity=22.7513227513227, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17864214, Length=464, Percent_Identity=24.3534482758621, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24654573, Length=401, Percent_Identity=24.4389027431421, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24657106, Length=474, Percent_Identity=24.4725738396624, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24657102, Length=474, Percent_Identity=24.4725738396624, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920476, Length=495, Percent_Identity=23.2323232323232, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356607, Length=321, Percent_Identity=22.1183800623053, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 53127; Mature: 53127

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00933 FGGY_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGIDLGTSEVKALVIDENNEIVATHSAPLTIQRPHPHWSEQSPQAWWEATEYLMTTLR
CEEEEECCCCCEEEEEEECCCCEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
EKCGHHWQAIKAIGLSGQMHGAVLLDEKGEAIRPAILWNDTRSAQECAELEEIAPELHQV
HHHCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
AGNLAMPGFTAPKLLWVRRHEPQHFARISTVLLPKDYLRFKMTGQKISDMSDSAGTLWLD
HCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHEEECCCHHHCCCCCCCEEEEE
VEKRDWSDSLLEKCGLTRANMPELVEGCDVSATLSPEVASRWGLTSSVVVAGGGGDNAVS
ECCCCCHHHHHHHHCCCCCCCHHHHHCCCCCEECCHHHHHHCCCCCEEEEECCCCCCCHH
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASC
HEECCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQWFCRLVGVTETELLEEIAQLSDADKASAPMFLPYLSGERTPHNDPHARGMFWGLTHSS
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCC
QRALMGYAVLEGVSFGIADGLRVLQESGTAIEQCSLVGGGARSPFWAQLLADILDMPVVT
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
HKGGETGGALGAARLACLATGKPLAAVCEKPEIFKTWRSDPERHKALMQRYQQFTALYHN
ECCCCCCCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
DLNYRNQ
CCCCCCC
>Mature Secondary Structure
MYLGIDLGTSEVKALVIDENNEIVATHSAPLTIQRPHPHWSEQSPQAWWEATEYLMTTLR
CEEEEECCCCCEEEEEEECCCCEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
EKCGHHWQAIKAIGLSGQMHGAVLLDEKGEAIRPAILWNDTRSAQECAELEEIAPELHQV
HHHCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
AGNLAMPGFTAPKLLWVRRHEPQHFARISTVLLPKDYLRFKMTGQKISDMSDSAGTLWLD
HCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHEEECCCHHHCCCCCCCEEEEE
VEKRDWSDSLLEKCGLTRANMPELVEGCDVSATLSPEVASRWGLTSSVVVAGGGGDNAVS
ECCCCCHHHHHHHHCCCCCCCHHHHHCCCCCEECCHHHHHHCCCCCEEEEECCCCCCCHH
AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASC
HEECCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQWFCRLVGVTETELLEEIAQLSDADKASAPMFLPYLSGERTPHNDPHARGMFWGLTHSS
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCC
QRALMGYAVLEGVSFGIADGLRVLQESGTAIEQCSLVGGGARSPFWAQLLADILDMPVVT
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
HKGGETGGALGAARLACLATGKPLAAVCEKPEIFKTWRSDPERHKALMQRYQQFTALYHN
ECCCCCCCHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
DLNYRNQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]