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The map label for this gene is cat [H]

Identifier: 218549454

GI number: 218549454

Start: 2151474

End: 2152154

Strand: Reverse

Name: cat [H]

Synonym: EFER_2123

Alternate gene names: 218549454

Gene position: 2152154-2151474 (Counterclockwise)

Preceding gene: 218549455

Following gene: 218549453

Centisome position: 46.9

GC content: 32.89

Gene sequence:

>681_bases
ATGGGACTTCTAAGTAGAATTAAATCACATTTAAAAAAAAGAAAATTGAATAAAAGTCACTTAAATATATATGTTGATGT
TTTTTCTTATATTGATGAGTCTTCAACTTTAGATGGTTGTAACAGAATAACTGGAAAATCATCAATTTATGACTCTCATA
TTGGGAAATATAGTTATGTTGCCGGAGCAAGCATAGGAAATGCGACAGTGGGAAAATTTTGCAGTATTGCAAAAGGAGCT
AAAATAGGAGGGCTTGGTGCGCATCCAACAACTTTCATATCTTCTCATCCTATCTTTTATTCTACTAAGAAACAATGTGG
GGTTACGTTTACTAGTAAGGATTATTTTTTAGAAAATGCGGATACAATATTAGGAAATGATGTATGGGTGGGTACGAATG
CCATCATTATGGATGGGGTAACAATTGGTGATGGTGCCATAATAGGTGCAGGTGCAATTGTTACAAAAGACGTTCCACCA
TATGCAATCGTTGTTGGTGTTCCGGCAATTATAAAACGATACCGTTTTCCAACTGAACAGATTGAAATTTTAAAAAAAAT
TAAATGGTGGGATTGGCCTGAACAAGACCTAAAAAAAAATTCATTCCTATTTCGAGAGGATTTTAATGAAAGTATCTGTG
AGTTAGCTAAATTATATAATAAAGTTAAAAGGCTAGATTAA

Upstream 100 bases:

>100_bases
GATTATTATTTAGCTCACTTACATTATTTCAGGAAAAATCAACAAAATTTTATTTATAAAATTTATTCATTTGTGAAAAA
GATAGTAAAAAAGAGGTGCT

Downstream 100 bases:

>100_bases
TGCAAACAGTGAATAATCATTTTTATAAAACTTTACTTCTATTAAGTTTTTTCTCTGCAGGGTTTAGTCTGTATTACGTA
TTTATACCGTTATTAATAAT

Product: chloramphenicol acetyltransferase (fragment)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGLLSRIKSHLKKRKLNKSHLNIYVDVFSYIDESSTLDGCNRITGKSSIYDSHIGKYSYVAGASIGNATVGKFCSIAKGA
KIGGLGAHPTTFISSHPIFYSTKKQCGVTFTSKDYFLENADTILGNDVWVGTNAIIMDGVTIGDGAIIGAGAIVTKDVPP
YAIVVGVPAIIKRYRFPTEQIEILKKIKWWDWPEQDLKKNSFLFREDFNESICELAKLYNKVKRLD

Sequences:

>Translated_226_residues
MGLLSRIKSHLKKRKLNKSHLNIYVDVFSYIDESSTLDGCNRITGKSSIYDSHIGKYSYVAGASIGNATVGKFCSIAKGA
KIGGLGAHPTTFISSHPIFYSTKKQCGVTFTSKDYFLENADTILGNDVWVGTNAIIMDGVTIGDGAIIGAGAIVTKDVPP
YAIVVGVPAIIKRYRFPTEQIEILKKIKWWDWPEQDLKKNSFLFREDFNESICELAKLYNKVKRLD
>Mature_225_residues
GLLSRIKSHLKKRKLNKSHLNIYVDVFSYIDESSTLDGCNRITGKSSIYDSHIGKYSYVAGASIGNATVGKFCSIAKGAK
IGGLGAHPTTFISSHPIFYSTKKQCGVTFTSKDYFLENADTILGNDVWVGTNAIIMDGVTIGDGAIIGAGAIVTKDVPPY
AIVVGVPAIIKRYRFPTEQIEILKKIKWWDWPEQDLKKNSFLFREDFNESICELAKLYNKVKRLD

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=84, Percent_Identity=36.9047619047619, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 25050; Mature: 24919

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLSRIKSHLKKRKLNKSHLNIYVDVFSYIDESSTLDGCNRITGKSSIYDSHIGKYSYV
CCHHHHHHHHHHHHCCCHHHHEEEEEHHHHHCCCCCCCHHHHCCCCCHHHHHHCCCEEEE
AGASIGNATVGKFCSIAKGAKIGGLGAHPTTFISSHPIFYSTKKQCGVTFTSKDYFLENA
ECCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEECCHHCCEEECCCCHHHCCC
DTILGNDVWVGTNAIIMDGVTIGDGAIIGAGAIVTKDVPPYAIVVGVPAIIKRYRFPTEQ
CCCCCCCEEECCCEEEECCEEECCCCEEECCEEEECCCCCEEEEECCHHHHHHHCCCHHH
IEILKKIKWWDWPEQDLKKNSFLFREDFNESICELAKLYNKVKRLD
HHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLLSRIKSHLKKRKLNKSHLNIYVDVFSYIDESSTLDGCNRITGKSSIYDSHIGKYSYV
CHHHHHHHHHHHHCCCHHHHEEEEEHHHHHCCCCCCCHHHHCCCCCHHHHHHCCCEEEE
AGASIGNATVGKFCSIAKGAKIGGLGAHPTTFISSHPIFYSTKKQCGVTFTSKDYFLENA
ECCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEEECCHHCCEEECCCCHHHCCC
DTILGNDVWVGTNAIIMDGVTIGDGAIIGAGAIVTKDVPPYAIVVGVPAIIKRYRFPTEQ
CCCCCCCEEECCCEEEECCEEECCCCEEECCEEEECCCCCEEEEECCHHHHHHHCCCHHH
IEILKKIKWWDWPEQDLKKNSFLFREDFNESICELAKLYNKVKRLD
HHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]