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The map label for this gene is ugd [H]

Identifier: 218549442

GI number: 218549442

Start: 2136353

End: 2137546

Strand: Reverse

Name: ugd [H]

Synonym: EFER_2111

Alternate gene names: 218549442

Gene position: 2137546-2136353 (Counterclockwise)

Preceding gene: 218549443

Following gene: 218549441

Centisome position: 46.58

GC content: 42.38

Gene sequence:

>1194_bases
ATGTTAAACCGGAAGAAGTCAGAGCTAATGAAAATAACAATTTCAGGAACAGGTTATGTTGGTCTTTCAAATGGTATTCT
GATTGCGCAAAACCACGAAGTGGTTGCACTGGATATCGTTCAGGCCAAAGTGGACATGCTTAACAAGAAGCAGTCACCGA
TTGTTGATAAGGAGATTGAAGAGTATCTGGCGACTAAAGATCTCAATTTCCGTGCTACGACAGATAAGTATGACGCGTAT
AAAAATGCCGATTACGTTATTATTGCCACGCCTACCGATTATGACCCGAAAACAAATTATTTTAATACCTCAAGCGTGGA
AGCGGTCATCCGTGATGTGACAGAGATTAACCCTAACGCTGTAATGGTGATTAAATCTACAATTCCGGTAGGTTTTACCA
AATCAATTAAAGAACGTCTGGGTATCGATAACCTTATTTTCTCTCCGGAATTCCTCCGCGAAGGTAAAGCACTTTACGAC
AATCTCCATCCTTCACGTATTGTCATCGGTGAGCGTTCAGAACGCGCAGAACGTTTTGCTGCGTTATTACAGGAGGGCGC
GATTAAGCAAAATATCCCGACTCTGTTTACCGACTCAACCGAAGCTGAAGCGATTAAACTTTTTGCAAATACCTATCTGG
CGATGCGCGTAGCGTACTTTAATGAACTGGATAGTTATGCAGAAAGTTTAGGTTTGAATACCCGACAGATTATCGAAGGT
GTTTGTCTTGACCCGCGTATCGGCAACCATTACAACAACCCTTCGTTTGGTTACGGTGGTTATTGTTTGCCGAAAGATAC
CAAGCAACTTCTGGCAAACTACCAATCTGTGCCGAATAACCTGATCTCAGCAATTGTCGATGCTAACCGCACGCGTAAAG
ACTTTATTGCCGATGCCATTTTGTCACGCAAACCGCAAGTGGTGGGTATTTATCGTCTGATTATGAAGAGTGGTTCAGAT
AACTTCCGTGCTTCCTCTATCCAGGGGATTATGAAGCGAATTAAAGCGAAAGGCGTGGAAGTGATCATCTATGAACCCGT
TATGAAAGAAGAATCATTTTTTAACTCACGTCTGGAACGAGACCTCACCACTTTCAAGCAACAATCTGATGTTATCATCT
CTAATCGCATGTCTACAGAACTGGACGATGTAAGAGAAAAAGTGTATACACGTGACCTTTTTGGCAGCGATTAA

Upstream 100 bases:

>100_bases
GAGCCGCACAGCAGGATCGCTGCCTTGACAGTTCATCTACATCAGCGTTAAAAATCCCGCAGTGGATGAAGATGTGGTGG
TGGATTAATGACCACTCTAA

Downstream 100 bases:

>100_bases
TTTTTCAGACCTGATTATAATTCCAATTATGCCTGATAGCCTCACTATTCAGGCATTTTGGTATGTAAGCCTGATATCAT
ATAATACATAATTTATGTGA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLNRKKSELMKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSPIVDKEIEEYLATKDLNFRATTDKYDAY
KNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYD
NLHPSRIVIGERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEG
VCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSD
NFRASSIQGIMKRIKAKGVEVIIYEPVMKEESFFNSRLERDLTTFKQQSDVIISNRMSTELDDVREKVYTRDLFGSD

Sequences:

>Translated_397_residues
MLNRKKSELMKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSPIVDKEIEEYLATKDLNFRATTDKYDAY
KNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYD
NLHPSRIVIGERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEG
VCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSD
NFRASSIQGIMKRIKAKGVEVIIYEPVMKEESFFNSRLERDLTTFKQQSDVIISNRMSTELDDVREKVYTRDLFGSD
>Mature_397_residues
MLNRKKSELMKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSPIVDKEIEEYLATKDLNFRATTDKYDAY
KNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYD
NLHPSRIVIGERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEG
VCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSD
NFRASSIQGIMKRIKAKGVEVIIYEPVMKEESFFNSRLERDLTTFKQQSDVIISNRMSTELDDVREKVYTRDLFGSD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=377, Percent_Identity=27.8514588859416, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI296040438, Length=269, Percent_Identity=26.3940520446097, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI296040443, Length=239, Percent_Identity=26.3598326359833, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=87.1134020618557, Blast_Score=702, Evalue=0.0,
Organism=Escherichia coli, GI48994968, Length=376, Percent_Identity=25, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17560350, Length=407, Percent_Identity=26.044226044226, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136908, Length=376, Percent_Identity=27.1276595744681, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 44784; Mature: 44784

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRKKSELMKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSPIVDKEIE
CCCCCCCCEEEEEECCCCEEEECCCEEEECCCCEEEEHHHHHHHHHHCCCCCCCHHHHHH
EYLATKDLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNA
HHHHHCCCCEEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCE
VMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYDNLHPSRIVIGERSERAERFA
EEEEECCCCCCHHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHH
ALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEG
HHHHHCCHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
VCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAI
CCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEESFFNSRLER
HHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHH
DLTTFKQQSDVIISNRMSTELDDVREKVYTRDLFGSD
HHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNRKKSELMKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSPIVDKEIE
CCCCCCCCEEEEEECCCCEEEECCCEEEECCCCEEEEHHHHHHHHHHCCCCCCCHHHHHH
EYLATKDLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNA
HHHHHCCCCEEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCE
VMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYDNLHPSRIVIGERSERAERFA
EEEEECCCCCCHHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHH
ALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNTRQIIEG
HHHHHCCHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
VCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAI
CCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEESFFNSRLER
HHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHH
DLTTFKQQSDVIISNRMSTELDDVREKVYTRDLFGSD
HHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]