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The map label for this gene is pocR [H]

Identifier: 218549339

GI number: 218549339

Start: 2059035

End: 2059952

Strand: Reverse

Name: pocR [H]

Synonym: EFER_2006

Alternate gene names: 218549339

Gene position: 2059952-2059035 (Counterclockwise)

Preceding gene: 218549340

Following gene: 218549338

Centisome position: 44.89

GC content: 41.61

Gene sequence:

>918_bases
ATGATTTCTGCCAGTACATTAAACTCAGAACTCATTAATAAAATCGCGCAGGATTTTGCACAAGCTACCAGCCTGGCGGT
TGTCATTGTGAACATCCACGGTGACGAAATTTCGCAACTTTTTAACTTTACCCCTTTTTGCCAACTGATGCGCCAACATC
CTCAGCATAGCGAACGCTGCCGAATGAGTGATCGCTGCGGTGGCTTTGAGTCGTCAAAGTCTGAAAAGCCGTGTATTTAT
CGCTGCCATGCGGGGTTAACAGATTTTTCGATTCCATTGGTGATTGCCGGTCATTTGGTTGGTTTTGTGTTATGTGGTCA
GGTGCGTTTACGTAATGATGGCGATGCTGATTTAGTTGATATTTTAAATATCGATAATTGTTGGCAAGCTGATCCTGATT
TACTGAATGAATTTCGCAAAGTTCCAGAGATGGATTATTCAAGAGTGATGGCGTCAGCCGACCTGCTGAAGCTTATTGTT
GAAAACTGTCTTAAGAATCAGCTCAATTTTATTGTTATCAAAGAGAGTAAGCCAGGTTCTGAAATAGCCCGTCAAAGTCG
AGCATCAAGTCCGCACGATAATAAAATGAAAAAAGCATTGCGTTATATCGATGCACATTTATCAGACGATTTGCGTCTGG
AGGATGTGGCCTCTCACGTTTATCTAAGCCCTTATTATTTCAGTAAATTATTTAAAAAATATAATGGAATTGGTTTTAAT
GCTTGGGTTAATCAACAGAGAATGGCCAGCGCCCGTGAATTACTTAGCCACAGTGACTGGAGTATTAGCAGCATTGCGCG
AAATCTCGGTTTCTCGCAAACCAGCTATTTTTGCAAAGTGTTTCGTCAGACATACCAGATAACACCGCAAGCATATCGTC
AGCAAATCAACGAAAATGCTATTGCACAGATGGCCTGA

Upstream 100 bases:

>100_bases
GTCCGTTTTGTTTTCTGGCAATGAAATGGAATGGTAACGCAGAAAAACAAAATTCGCTTTATATATTCATTATATCAATA
ATTCAAATAAGGGATTTTAT

Downstream 100 bases:

>100_bases
TTAATTGGTAAATAATATGGAGGTTTTTGTAAATTCGTCATGCTTCAGGTTGCATATGCTGCAACGCGAATTATTTAAAG
TACAGACGTAAATATCGTGT

Product: Propanediol utilization: transcriptional regulation

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MISASTLNSELINKIAQDFAQATSLAVVIVNIHGDEISQLFNFTPFCQLMRQHPQHSERCRMSDRCGGFESSKSEKPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDGDADLVDILNIDNCWQADPDLLNEFRKVPEMDYSRVMASADLLKLIV
ENCLKNQLNFIVIKESKPGSEIARQSRASSPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYNGIGFN
AWVNQQRMASARELLSHSDWSISSIARNLGFSQTSYFCKVFRQTYQITPQAYRQQINENAIAQMA

Sequences:

>Translated_305_residues
MISASTLNSELINKIAQDFAQATSLAVVIVNIHGDEISQLFNFTPFCQLMRQHPQHSERCRMSDRCGGFESSKSEKPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDGDADLVDILNIDNCWQADPDLLNEFRKVPEMDYSRVMASADLLKLIV
ENCLKNQLNFIVIKESKPGSEIARQSRASSPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYNGIGFN
AWVNQQRMASARELLSHSDWSISSIARNLGFSQTSYFCKVFRQTYQITPQAYRQQINENAIAQMA
>Mature_305_residues
MISASTLNSELINKIAQDFAQATSLAVVIVNIHGDEISQLFNFTPFCQLMRQHPQHSERCRMSDRCGGFESSKSEKPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDGDADLVDILNIDNCWQADPDLLNEFRKVPEMDYSRVMASADLLKLIV
ENCLKNQLNFIVIKESKPGSEIARQSRASSPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYNGIGFN
AWVNQQRMASARELLSHSDWSISSIARNLGFSQTSYFCKVFRQTYQITPQAYRQQINENAIAQMA

Specific function: Positive regulatory protein of pdu and cob operons [H]

COG id: COG4936

COG function: function code TK; Predicted sensor domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790391, Length=118, Percent_Identity=37.2881355932203, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786251, Length=116, Percent_Identity=35.3448275862069, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788725, Length=91, Percent_Identity=34.0659340659341, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR018771 [H]

Pfam domain/function: PF10114 Hist_Kin_Sens; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34642; Mature: 34642

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISASTLNSELINKIAQDFAQATSLAVVIVNIHGDEISQLFNFTPFCQLMRQHPQHSERC
CCCHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHCCCHHHHHHHHCCCHHHHH
RMSDRCGGFESSKSEKPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDGDADLVD
CHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHH
ILNIDNCWQADPDLLNEFRKVPEMDYSRVMASADLLKLIVENCLKNQLNFIVIKESKPGS
HCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHH
EIARQSRASSPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYNGIGFN
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHH
AWVNQQRMASARELLSHSDWSISSIARNLGFSQTSYFCKVFRQTYQITPQAYRQQINENA
HHHCHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IAQMA
HHHCC
>Mature Secondary Structure
MISASTLNSELINKIAQDFAQATSLAVVIVNIHGDEISQLFNFTPFCQLMRQHPQHSERC
CCCHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHCCCHHHHHHHHCCCHHHHH
RMSDRCGGFESSKSEKPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLRNDGDADLVD
CHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHH
ILNIDNCWQADPDLLNEFRKVPEMDYSRVMASADLLKLIVENCLKNQLNFIVIKESKPGS
HCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHH
EIARQSRASSPHDNKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYNGIGFN
HHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHH
AWVNQQRMASARELLSHSDWSISSIARNLGFSQTSYFCKVFRQTYQITPQAYRQQINENA
HHHCHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IAQMA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8071226; 9352910; 11677609; 8501034 [H]