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The map label for this gene is ydcR [H]

Identifier: 218548868

GI number: 218548868

Start: 1548413

End: 1549819

Strand: Direct

Name: ydcR [H]

Synonym: EFER_1513

Alternate gene names: 218548868

Gene position: 1548413-1549819 (Clockwise)

Preceding gene: 218548866

Following gene: 218548869

Centisome position: 33.74

GC content: 51.31

Gene sequence:

>1407_bases
ATGAAAAAATACCAGCAGCTTGCAGAACAATTACGCGAGCAGATTGCGTCGGGTATCTGGCAACCCGGCGATCGTTTACC
TTCGTTGCGTGACCAGGTGGCGCTTTCTGGCATGAGCTTTATGACCGTCAGCCATGCCTATCAGTTGCTCGAAAGTCAGG
GACATATTATCGCGCGACCGCAGTCGGGTTATTACGTTGCGCCACAGGCAATAAAAATGCCGAAAGCGCCAGTCATTCCA
GTCACTCGAGATGAAGCAGTCGATATCAATACCTATATTTTTGATATGTTGCAGGCCAGCCGCGATCCGTCGGTAGTTCC
GTTTGCCTCGGCCTTTCCCGACCCGCGACTTTTCCCCCTCCAACAACTGAACCGCTCGCTGGCGCAGGTAAGCAAAACCG
CCACGGCGATGAGCGTGATTGAAAACTTACCGCCAGGAAACGCAGAACTGCGTCAGGCTATTGCTCGTCGCTATGCCTTA
CAGGGCATCACTATTTCTCCCGATGAAATTGTTATTACCGCCGGGGCGTTAGAGGCATTAAACCTCAGTTTACAAGCGGT
AACGGAACCAGGCGATTGGGTGATAGTAGAGAATCCTTGTTTCTACGGCGCGTTGCAGGCACTGGAGCGGTTACGGCTGA
AGGCGTTATCGGTGGCGACGGATGTTAACGAAGGGATCGATCTCAAGGCGCTGGAACTGGCGTTGCAGGAGTATCCGGTG
AAAGCGTGCTGGCTGATGACTAATAGCCAGAATCCACTCGGGTTTACCTTAACGCCACAGAAAAAAGCGCGACTGGTAGC
GTTGCTCAATCAGTACAACGTAACGCTGATTGAAGATGACGTGTATAGCGAACTTTATTTTGGACGGGAAAAACCGCTGC
CTGCGAAAGCGTGGGATCGCCACGATGGCGTTTTGCATTGCTCTTCGTTTTCGAAATGTCTGGTGCCAGGTTTTCGTATT
GGTTGGGTCGTCGCCGGAAAACACGCACGCAAAATTCAACGCTTGCAATTGATGAGTACGCTTTCGACCAGTTCACCGAT
GCAGCTTGCGCTGGTGGATTATTTTTCCACGCGCCGTTACGACGCCCATCTTCGTCGCCTGCGTCGCCAGCTTGCGGAAC
GTAAACAACGTGTCTGGCAGGCACTGCTGCGTTATCTGCCTGCGGAAGTGAAAATTCATCATAATGACAGCGGTTATTTT
CTCTGGCTGGAACTCCCCGCGCCGTTAGATGCGGGCGAATTAAGTATTCAGGCATTGGCGCATCATATCAGTATTGCGCC
GGGTAAAATGTTTTCTACTGGCGAAAGTTGGTCATGTTTTTTCCGTTTTAATACTGCATGGCAGTGGGGCGAGCGCGAAG
AACAGGCGGTTAAACAATTAGGCAAACTTATTCAAGAACGGCTGTAA

Upstream 100 bases:

>100_bases
TTTTAAGGTTACTGTTCTGTTATGAAAATTAGAGTAAAGTTGTCATTTTTAACAACTGATATAGACTGCCGGGTAATCTA
CAAATCATAACAATACGATA

Downstream 100 bases:

>100_bases
TAGCGTTAAATTTAATTCCTCTTAGGTTGGGTAATATGAATTTCGAATAGCAGTCATATTTCCTAACCCCTTGTCTATAC
TCCAGAAGATAACCTCGCAG

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGHIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVNEGIDLKALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKARLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVVAGKHARKIQRLQLMSTLSTSSPMQLALVDYFSTRRYDAHLRRLRRQLAERKQRVWQALLRYLPAEVKIHHNDSGYF
LWLELPAPLDAGELSIQALAHHISIAPGKMFSTGESWSCFFRFNTAWQWGEREEQAVKQLGKLIQERL

Sequences:

>Translated_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGHIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVNEGIDLKALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKARLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVVAGKHARKIQRLQLMSTLSTSSPMQLALVDYFSTRRYDAHLRRLRRQLAERKQRVWQALLRYLPAEVKIHHNDSGYF
LWLELPAPLDAGELSIQALAHHISIAPGKMFSTGESWSCFFRFNTAWQWGEREEQAVKQLGKLIQERL
>Mature_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGHIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVNEGIDLKALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKARLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVVAGKHARKIQRLQLMSTLSTSSPMQLALVDYFSTRRYDAHLRRLRRQLAERKQRVWQALLRYLPAEVKIHHNDSGYF
LWLELPAPLDAGELSIQALAHHISIAPGKMFSTGESWSCFFRFNTAWQWGEREEQAVKQLGKLIQERL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=401, Percent_Identity=25.9351620947631, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI33469970, Length=401, Percent_Identity=25.9351620947631, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4507369, Length=244, Percent_Identity=24.5901639344262, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI56713256, Length=343, Percent_Identity=24.4897959183673, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI56713254, Length=343, Percent_Identity=24.4897959183673, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=97.2222222222222, Blast_Score=938, Evalue=0.0,
Organism=Escherichia coli, GI1790797, Length=466, Percent_Identity=34.7639484978541, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI1788722, Length=314, Percent_Identity=25.1592356687898, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=182, Percent_Identity=25.8241758241758, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321000, Length=219, Percent_Identity=27.3972602739726, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356535, Length=331, Percent_Identity=24.773413897281, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI18859735, Length=191, Percent_Identity=28.2722513089005, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52760; Mature: 52760

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGHIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECC
QSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVNEGIDLKALELALQEYPV
CCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLTPQKKARLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVVAGKHARKIQRLQLMSTLSTSSPMQLALVDYFSTRRY
CCCEEEECCCCHHHCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCHH
DAHLRRLRRQLAERKQRVWQALLRYLPAEVKIHHNDSGYFLWLELPAPLDAGELSIQALA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHH
HHISIAPGKMFSTGESWSCFFRFNTAWQWGEREEQAVKQLGKLIQERL
HHHCCCCCCEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGHIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEECC
QSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVNEGIDLKALELALQEYPV
CCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLTPQKKARLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVVAGKHARKIQRLQLMSTLSTSSPMQLALVDYFSTRRY
CCCEEEECCCCHHHCCCCEEEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCHH
DAHLRRLRRQLAERKQRVWQALLRYLPAEVKIHHNDSGYFLWLELPAPLDAGELSIQALA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHH
HHISIAPGKMFSTGESWSCFFRFNTAWQWGEREEQAVKQLGKLIQERL
HHHCCCCCCEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]