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The map label for this gene is motA [H]

Identifier: 218548502

GI number: 218548502

Start: 1171973

End: 1172860

Strand: Direct

Name: motA [H]

Synonym: EFER_1131

Alternate gene names: 218548502

Gene position: 1171973-1172860 (Clockwise)

Preceding gene: 218548501

Following gene: 218548503

Centisome position: 25.54

GC content: 51.01

Gene sequence:

>888_bases
GTGCTTATCATATTAGGTTACCTGGTTGTTATCGGTACAGTTTTCGGCGGTTACTTAATGACCGGCGGAAGTCTTGGAGC
ACTCTATCAACCTGCTGAGTTGGTGATTATTGCTGGTGCCGGAATCGGGGCATTTATCGTTGGCAACAACGGTAAAGCGA
TCAAAGGAACCCTCAAGGCGTTACCGCTCTTGTTTCGTCGCTCGAAATATAGCAAAGCGATGTATATGGATCTGCTGGCG
CTGCTTTACCGCCTGATGGCGAAATCACGCCAGCAGGGGATGTTTTCTCTTGAACGGGATATTGAAAACCCCCAGGAAAG
TGAAATTTTTGCCAGTTACCCGCGTATTCTGGCAGACAGCGTAATGCTTGAATTTATTGTCGATTATCTACGTCTGATCA
TCAGCGGTCATATGAACAGCTTTGAAATTGAAGCGTTGATGGACGAAGAGATCGAAACCCATGAAAGTGAAGCAGAAGTA
CCAGCCAATAGCCTGGCAATTGTTGGCGATTCTCTCCCCGCGTTTGGCATTGTTGCGGCGGTAATGGGCGTTGTTCATGC
CCTGGGATCGGCTGATCGACCCGCTGCGGAGTTAGGGGCGCTGATCGCCCACGCTATGGTGGGCACTTTCCTCGGTATTT
TGCTCGCTTACGGATTTATCTCGCCGCTGGCCGGAGTGTTACGGCAGAAAAGCGCCGAAACCACCAAGATGATGCAGTGC
GTCAAAGTGACACTGCTTTCCAGTCTGAATGGCTATGCCCCACCGATTGCCGTCGAGTTTGGTCGCAAGACGCTTTACTC
CAGTGAGCGCCCGTCATTTGTGGAGCTGGAAGAACATGTCCGCGCCGTGAAAAACCCGAATCAGCAGGCCACTACCGAGG
AAGTATGA

Upstream 100 bases:

>100_bases
CCAGCAGCGGTCACTCTCCACCGCTGCTTTTTTTGCCACTTCACCCGGTTAATCCTTCGACTGCTCATCCTGTCATGATC
AACAGTGGAAGGATGATGTC

Downstream 100 bases:

>100_bases
AGAATCGTGATCAACCTATTATCGTCGTTAAAAGGCGTAAGCCCAAAAACCACGGCGGCGCGGGGCATGGTTCGTGGAAA
ATTGCCTACGCCGATTTTAT

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLIILGYLVVIGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGAFIVGNNGKAIKGTLKALPLLFRRSKYSKAMYMDLLA
LLYRLMAKSRQQGMFSLERDIENPQESEIFASYPRILADSVMLEFIVDYLRLIISGHMNSFEIEALMDEEIETHESEAEV
PANSLAIVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYGFISPLAGVLRQKSAETTKMMQC
VKVTLLSSLNGYAPPIAVEFGRKTLYSSERPSFVELEEHVRAVKNPNQQATTEEV

Sequences:

>Translated_295_residues
MLIILGYLVVIGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGAFIVGNNGKAIKGTLKALPLLFRRSKYSKAMYMDLLA
LLYRLMAKSRQQGMFSLERDIENPQESEIFASYPRILADSVMLEFIVDYLRLIISGHMNSFEIEALMDEEIETHESEAEV
PANSLAIVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYGFISPLAGVLRQKSAETTKMMQC
VKVTLLSSLNGYAPPIAVEFGRKTLYSSERPSFVELEEHVRAVKNPNQQATTEEV
>Mature_295_residues
MLIILGYLVVIGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGAFIVGNNGKAIKGTLKALPLLFRRSKYSKAMYMDLLA
LLYRLMAKSRQQGMFSLERDIENPQESEIFASYPRILADSVMLEFIVDYLRLIISGHMNSFEIEALMDEEIETHESEAEV
PANSLAIVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYGFISPLAGVLRQKSAETTKMMQC
VKVTLLSSLNGYAPPIAVEFGRKTLYSSERPSFVELEEHVRAVKNPNQQATTEEV

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=294, Percent_Identity=94.8979591836735, Blast_Score=569, Evalue=1e-164,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 31864; Mature: 31864

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIILGYLVVIGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGAFIVGNNGKAIKGTLKA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHH
LPLLFRRSKYSKAMYMDLLALLYRLMAKSRQQGMFSLERDIENPQESEIFASYPRILADS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHH
VMLEFIVDYLRLIISGHMNSFEIEALMDEEIETHESEAEVPANSLAIVGDSLPAFGIVAA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHH
VMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYGFISPLAGVLRQKSAETTKMMQC
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVTLLSSLNGYAPPIAVEFGRKTLYSSERPSFVELEEHVRAVKNPNQQATTEEV
HHHHHHHHCCCCCCCHHHHHCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLIILGYLVVIGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGAFIVGNNGKAIKGTLKA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHH
LPLLFRRSKYSKAMYMDLLALLYRLMAKSRQQGMFSLERDIENPQESEIFASYPRILADS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHH
VMLEFIVDYLRLIISGHMNSFEIEALMDEEIETHESEAEVPANSLAIVGDSLPAFGIVAA
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHH
VMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYGFISPLAGVLRQKSAETTKMMQC
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVTLLSSLNGYAPPIAVEFGRKTLYSSERPSFVELEEHVRAVKNPNQQATTEEV
HHHHHHHHCCCCCCCHHHHHCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]