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The map label for this gene is ycaM [H]

Identifier: 218548418

GI number: 218548418

Start: 1077142

End: 1078572

Strand: Direct

Name: ycaM [H]

Synonym: EFER_1046

Alternate gene names: 218548418

Gene position: 1077142-1078572 (Clockwise)

Preceding gene: 218548417

Following gene: 218548423

Centisome position: 23.47

GC content: 43.96

Gene sequence:

>1431_bases
ATGGCGCGTAATGGGCAGGAAAAACAGTTGCGATGGTACAATATTGCATTGATGTCATTTATTACAGTCTGGGGATTTGG
CAATGTTGTTAATAATTATGCAAACCAGGGATTAGTGGTAGTTTTCTCATGGTTGTTTATATTTATCCTTTATTTTACTC
CGTATGCTCTTATTGTCGGACAACTGGGTTCAACGTTTAAAGATGGGAAGGGCGGAGTTAGCACCTGGATTAAGCATACT
ATGGGGCCAGGACTGGCTTATCTTGCCGCATGGACCTATTGGGTGGTGCATATTCCTTACCTGGCACAAAAACCTCAAAC
AATTCTGATTGCTCTTGGTTGGGCCGTGAAAGGTGACGGTTCACTAATTAAAGAATACTCGGTGGTAGTATTACAGGGGC
TAACATTAGTGTTGTTTGTCTTCTTTATGTGGGTCGCATCGCGCGGTATGAAATCGCTGAAAACCGTCGGTTCGATTGCG
GGAATCGCGATGTTTGTAATGTCGCTGTTATATGTGGCGATGGCAGTAGCTGCACCGGCTATAACTGAAGTTCATATTGC
GACCACTAATATTACCTCGGAAACGTTTATTCCTCATATAGATTTCACCTACATAACGACTATTTCGATGTTAGTTTTTG
CAGTGGGCGGTGCTGAGAAGATTTCTCCTTACGTTAATCAAACGTGTAATCCGGGAAAAGAGTTTCCAAAAGGGATGCTA
TGTTTAGCAGCAATGGTTGCGGTGTGTGCAATTCTGGGATCGCTGGCGATGGGGATGATGTTTGACTCGCGGCATATTCC
GGATGATTTAATGACCAATGGGCAATATTATGCCTTCCAGAAATTGGGAGAGTATTACAATATGGGTAATTCCTTAATGG
TCATTTACGCCATTGCTAATACCCTTGGGCATGTTGCTGCACTGGTATTCTCAATTGATGCGCCACTGAAAGTCTTACTA
GGGGATGCAGACAGGAAATATATTCCTGCAAGATTGTGCCGTACAAATGATTCAGGAACACCAGTTAACGGGTATATTTT
GACGCTGGTGTTAGTGGCGATCCTGATAATGCTGCCAACGCTGGGTATTGGTGATATGAATAATCTCTACAAATGGTTGT
TGAATCTTAACTCGGTAGTGATGCCACTGCGTTATTTGTGGGTGTTTGTTGCATTTATTGCAGTCGTTCGCCTGGCGCAG
AAATATAAACCAGAGTATGTCTTTATTCGTAATAGATGGCTGGCGATGATCGTCGGGATTTGGTGTTTTGCCTTTACCGC
TTTTGCCTGTTTGACGGGGATCTTCCCGAAAATGGAAGCCTTCACTACCGAGTGGACTTTCCAGCTGGCGCTGAACATTG
CAACGCCGTTTGTGCTGGTAGGATTAGGGCTGATATTCCCGTTGTTGGCGCGTAAAGCGAATAGTGAATAA

Upstream 100 bases:

>100_bases
TAGGTTATATTTTTGCATTTCACTATTTCCGTCTCTTTCTTTTATCGCGCATAATCCCCGGATTTTCCAATAGCATTCAA
TTTTTAGCGAAGGATTGTTT

Downstream 100 bases:

>100_bases
TCGTTGTGGTCAGTTCTGCTAAGTCGGGCAGAGCTGACCCGTTTTTACATAATCGAGAAATGCACGCAATCCGCAGGACA
TATACTGGCGGTTTGGGTAA

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MARNGQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSWLFIFILYFTPYALIVGQLGSTFKDGKGGVSTWIKHT
MGPGLAYLAAWTYWVVHIPYLAQKPQTILIALGWAVKGDGSLIKEYSVVVLQGLTLVLFVFFMWVASRGMKSLKTVGSIA
GIAMFVMSLLYVAMAVAAPAITEVHIATTNITSETFIPHIDFTYITTISMLVFAVGGAEKISPYVNQTCNPGKEFPKGML
CLAAMVAVCAILGSLAMGMMFDSRHIPDDLMTNGQYYAFQKLGEYYNMGNSLMVIYAIANTLGHVAALVFSIDAPLKVLL
GDADRKYIPARLCRTNDSGTPVNGYILTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFIAVVRLAQ
KYKPEYVFIRNRWLAMIVGIWCFAFTAFACLTGIFPKMEAFTTEWTFQLALNIATPFVLVGLGLIFPLLARKANSE

Sequences:

>Translated_476_residues
MARNGQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSWLFIFILYFTPYALIVGQLGSTFKDGKGGVSTWIKHT
MGPGLAYLAAWTYWVVHIPYLAQKPQTILIALGWAVKGDGSLIKEYSVVVLQGLTLVLFVFFMWVASRGMKSLKTVGSIA
GIAMFVMSLLYVAMAVAAPAITEVHIATTNITSETFIPHIDFTYITTISMLVFAVGGAEKISPYVNQTCNPGKEFPKGML
CLAAMVAVCAILGSLAMGMMFDSRHIPDDLMTNGQYYAFQKLGEYYNMGNSLMVIYAIANTLGHVAALVFSIDAPLKVLL
GDADRKYIPARLCRTNDSGTPVNGYILTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFIAVVRLAQ
KYKPEYVFIRNRWLAMIVGIWCFAFTAFACLTGIFPKMEAFTTEWTFQLALNIATPFVLVGLGLIFPLLARKANSE
>Mature_475_residues
ARNGQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSWLFIFILYFTPYALIVGQLGSTFKDGKGGVSTWIKHTM
GPGLAYLAAWTYWVVHIPYLAQKPQTILIALGWAVKGDGSLIKEYSVVVLQGLTLVLFVFFMWVASRGMKSLKTVGSIAG
IAMFVMSLLYVAMAVAAPAITEVHIATTNITSETFIPHIDFTYITTISMLVFAVGGAEKISPYVNQTCNPGKEFPKGMLC
LAAMVAVCAILGSLAMGMMFDSRHIPDDLMTNGQYYAFQKLGEYYNMGNSLMVIYAIANTLGHVAALVFSIDAPLKVLLG
DADRKYIPARLCRTNDSGTPVNGYILTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFIAVVRLAQK
YKPEYVFIRNRWLAMIVGIWCFAFTAFACLTGIFPKMEAFTTEWTFQLALNIATPFVLVGLGLIFPLLARKANSE

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081798, Length=476, Percent_Identity=94.327731092437, Blast_Score=909, Evalue=0.0,
Organism=Escherichia coli, GI48994921, Length=420, Percent_Identity=22.8571428571429, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI87082380, Length=463, Percent_Identity=22.0302375809935, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787768, Length=434, Percent_Identity=23.7327188940092, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52754; Mature: 52623

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNGQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSWLFIFILYFTPYALIVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
QLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLAQKPQTILIALGWAVKGDG
HHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEEEECCC
SLIKEYSVVVLQGLTLVLFVFFMWVASRGMKSLKTVGSIAGIAMFVMSLLYVAMAVAAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ITEVHIATTNITSETFIPHIDFTYITTISMLVFAVGGAEKISPYVNQTCNPGKEFPKGML
HHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHHHHHH
CLAAMVAVCAILGSLAMGMMFDSRHIPDDLMTNGQYYAFQKLGEYYNMGNSLMVIYAIAN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
TLGHVAALVFSIDAPLKVLLGDADRKYIPARLCRTNDSGTPVNGYILTLVLVAILIMLPT
HHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
LGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFIAVVRLAQKYKPEYVFIRNRWLAMIVGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
WCFAFTAFACLTGIFPKMEAFTTEWTFQLALNIATPFVLVGLGLIFPLLARKANSE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARNGQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSWLFIFILYFTPYALIVG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
QLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLAQKPQTILIALGWAVKGDG
HHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEEEECCC
SLIKEYSVVVLQGLTLVLFVFFMWVASRGMKSLKTVGSIAGIAMFVMSLLYVAMAVAAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ITEVHIATTNITSETFIPHIDFTYITTISMLVFAVGGAEKISPYVNQTCNPGKEFPKGML
HHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHHHHHH
CLAAMVAVCAILGSLAMGMMFDSRHIPDDLMTNGQYYAFQKLGEYYNMGNSLMVIYAIAN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
TLGHVAALVFSIDAPLKVLLGDADRKYIPARLCRTNDSGTPVNGYILTLVLVAILIMLPT
HHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
LGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFIAVVRLAQKYKPEYVFIRNRWLAMIVGI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
WCFAFTAFACLTGIFPKMEAFTTEWTFQLALNIATPFVLVGLGLIFPLLARKANSE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]