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The map label for this gene is yliI [H]

Identifier: 218548356

GI number: 218548356

Start: 1010836

End: 1011948

Strand: Direct

Name: yliI [H]

Synonym: EFER_0978

Alternate gene names: 218548356

Gene position: 1010836-1011948 (Clockwise)

Preceding gene: 218548355

Following gene: 218548358

Centisome position: 22.03

GC content: 50.49

Gene sequence:

>1113_bases
ATGCGTCGTGTGCTTCTTTCCGTTATCTCTTTACTAATTTCTCCCCTGGTTTTTGCTACGCCCGCTGCGGTAAAAGTGGA
AGTATTGCAAACCAAACTCGATCATCCCTGGGCGCTGGCATTTTTACCCGATAATCAGGGAATTCTGATTACGCTAAAAG
GCGGACAACTTCGCCACTGGCAGGCAGGTAAAGGGTTATCTGATCCGCTTCCTGGCGTGCCGCAAGTTTGGGCTAATGGT
CAGGGTGGACTCCTTGATGTGGCGCTGGCACCTGATTTCACGACTTCTCGCCGGGTGTGGTTAAGTTTTGCCGAAGGAGA
TGCTAACGGCAAAGCCGGTACGGCAGTCGGTTATGGTCGCCTGAGTGAAGATCTCAGCCATCTTTCTGACTTCAAAACGG
TATTTCGTCAGACACCAAAGCTTTCGACAGGTAATCATTTTGGTGGACGATTGGTGTTTGATGGTAAAGGCTATTTGTTT
ATTGGGCTTGGGGAGAATAACCAACGGCCAACAGCTCAGGATCTCGATAAGTTGCAAGGGAAAGTGGTGCGACTTACCGA
CCAGGGCCAGATCCCTCCTGATAATCCCTTCGTTAATCAAGCCGCTGTGCGGCCTGAGATCTGGTCTTATGGTATCCGTA
ATCCTCAGGGAATGGCGATGAATCCTTGGAGCGATGCCCTGTGGCTGAACGAGCATGGCCCGCGTGGTGGCGATGAAATT
AATATTCCACAAAAGGGTAAAAATTACGGCTGGCCTCTGGCAACATGGGGAATCAACTATAGCGGCCTGAAGATCCCCGA
AGCAAAAGGGGAAATTGTGGCGGGTACGGAACAACCTATTTTTTACTGGAAAAAATCACCCGCTGTCAGCGGCATGGCGT
TCTATAACAGTGATACCTTTGCCCAGTGGCAACAAAAGTTGTTTATCGGTGCGTTAAAAGACAAGGATGTGATCGTGATG
AGCGTGAAGGGCGATAATGTCAGCGAAGATGGGCGCATTTTAGGCGACAGAGGTCAGCGTATTCGCGATGTACGTACAGG
ACCCGACGGCTATTTGTATGTCCTGACCGACGAGTCCGATGGCGAGTTGCTGAAAGTCAGCCCACGTCCCTGA

Upstream 100 bases:

>100_bases
CCGGGGGAGGCAACTCCCCCTTTTGGTTAAGTTTATGTAAAAATCAGCTCATGCTTCTGACTGATGACTACGCTTGAACG
AGAGTCATTAAGGAGGCGTT

Downstream 100 bases:

>100_bases
TGCTTTAACTGACCGGAATCATGACGACTTTACGAAACGCCGGGCGCTCTGTGAGTTGTTGATACCAGCGCTCAAGGTTA
GGGCGCGGAGTCCATGTCAG

Product: PQQ-dependent aldose sugar dehydrogenase

Products: NA

Alternate protein names: Asd [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRRVLLSVISLLISPLVFATPAAVKVEVLQTKLDHPWALAFLPDNQGILITLKGGQLRHWQAGKGLSDPLPGVPQVWANG
QGGLLDVALAPDFTTSRRVWLSFAEGDANGKAGTAVGYGRLSEDLSHLSDFKTVFRQTPKLSTGNHFGGRLVFDGKGYLF
IGLGENNQRPTAQDLDKLQGKVVRLTDQGQIPPDNPFVNQAAVRPEIWSYGIRNPQGMAMNPWSDALWLNEHGPRGGDEI
NIPQKGKNYGWPLATWGINYSGLKIPEAKGEIVAGTEQPIFYWKKSPAVSGMAFYNSDTFAQWQQKLFIGALKDKDVIVM
SVKGDNVSEDGRILGDRGQRIRDVRTGPDGYLYVLTDESDGELLKVSPRP

Sequences:

>Translated_370_residues
MRRVLLSVISLLISPLVFATPAAVKVEVLQTKLDHPWALAFLPDNQGILITLKGGQLRHWQAGKGLSDPLPGVPQVWANG
QGGLLDVALAPDFTTSRRVWLSFAEGDANGKAGTAVGYGRLSEDLSHLSDFKTVFRQTPKLSTGNHFGGRLVFDGKGYLF
IGLGENNQRPTAQDLDKLQGKVVRLTDQGQIPPDNPFVNQAAVRPEIWSYGIRNPQGMAMNPWSDALWLNEHGPRGGDEI
NIPQKGKNYGWPLATWGINYSGLKIPEAKGEIVAGTEQPIFYWKKSPAVSGMAFYNSDTFAQWQQKLFIGALKDKDVIVM
SVKGDNVSEDGRILGDRGQRIRDVRTGPDGYLYVLTDESDGELLKVSPRP
>Mature_370_residues
MRRVLLSVISLLISPLVFATPAAVKVEVLQTKLDHPWALAFLPDNQGILITLKGGQLRHWQAGKGLSDPLPGVPQVWANG
QGGLLDVALAPDFTTSRRVWLSFAEGDANGKAGTAVGYGRLSEDLSHLSDFKTVFRQTPKLSTGNHFGGRLVFDGKGYLF
IGLGENNQRPTAQDLDKLQGKVVRLTDQGQIPPDNPFVNQAAVRPEIWSYGIRNPQGMAMNPWSDALWLNEHGPRGGDEI
NIPQKGKNYGWPLATWGINYSGLKIPEAKGEIVAGTEQPIFYWKKSPAVSGMAFYNSDTFAQWQQKLFIGALKDKDVIVM
SVKGDNVSEDGRILGDRGQRIRDVRTGPDGYLYVLTDESDGELLKVSPRP

Specific function: Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PQQ oxidoreductase gdhB family [H]

Homologues:

Organism=Homo sapiens, GI187936953, Length=200, Percent_Identity=29.5, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI187936955, Length=200, Percent_Identity=29.5, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI124248546, Length=199, Percent_Identity=26.6331658291457, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787060, Length=368, Percent_Identity=82.6086956521739, Blast_Score=630, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 40586; Mature: 40586

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVLLSVISLLISPLVFATPAAVKVEVLQTKLDHPWALAFLPDNQGILITLKGGQLRHW
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCEEEEEEECCCCEEEEECCCCEEEE
QAGKGLSDPLPGVPQVWANGQGGLLDVALAPDFTTSRRVWLSFAEGDANGKAGTAVGYGR
ECCCCCCCCCCCCCHHEECCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCEEECHH
LSEDLSHLSDFKTVFRQTPKLSTGNHFGGRLVFDGKGYLFIGLGENNQRPTAQDLDKLQG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHCC
KVVRLTDQGQIPPDNPFVNQAAVRPEIWSYGIRNPQGMAMNPWSDALWLNEHGPRGGDEI
EEEEEECCCCCCCCCCCCCCHHCCCHHHHCCCCCCCCCEECCCCCEEEEECCCCCCCCEE
NIPQKGKNYGWPLATWGINYSGLKIPEAKGEIVAGTEQPIFYWKKSPAVSGMAFYNSDTF
CCCCCCCCCCCCEEECCCCCCCEECCCCCCCEEECCCCCEEEEECCCCCCEEEEECCCCH
AQWQQKLFIGALKDKDVIVMSVKGDNVSEDGRILGDRGQRIRDVRTGPDGYLYVLTDESD
HHHHHHHEEEEECCCCEEEEEECCCCCCCCCCEECCCCCEEEHHCCCCCCEEEEEEECCC
GELLKVSPRP
CCEEEECCCC
>Mature Secondary Structure
MRRVLLSVISLLISPLVFATPAAVKVEVLQTKLDHPWALAFLPDNQGILITLKGGQLRHW
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCEEEEEEECCCCEEEEECCCCEEEE
QAGKGLSDPLPGVPQVWANGQGGLLDVALAPDFTTSRRVWLSFAEGDANGKAGTAVGYGR
ECCCCCCCCCCCCCHHEECCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCEEECHH
LSEDLSHLSDFKTVFRQTPKLSTGNHFGGRLVFDGKGYLFIGLGENNQRPTAQDLDKLQG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHCC
KVVRLTDQGQIPPDNPFVNQAAVRPEIWSYGIRNPQGMAMNPWSDALWLNEHGPRGGDEI
EEEEEECCCCCCCCCCCCCCHHCCCHHHHCCCCCCCCCEECCCCCEEEEECCCCCCCCEE
NIPQKGKNYGWPLATWGINYSGLKIPEAKGEIVAGTEQPIFYWKKSPAVSGMAFYNSDTF
CCCCCCCCCCCCEEECCCCCCCEECCCCCCCEEECCCCCEEEEECCCCCCEEEEECCCCH
AQWQQKLFIGALKDKDVIVMSVKGDNVSEDGRILGDRGQRIRDVRTGPDGYLYVLTDESD
HHHHHHHEEEEECCCCEEEEEECCCCCCCCCCEECCCCCEEEHHCCCCCCEEEEEEECCC
GELLKVSPRP
CCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]