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The map label for this gene is dacC [H]

Identifier: 218548358

GI number: 218548358

Start: 1012826

End: 1014028

Strand: Direct

Name: dacC [H]

Synonym: EFER_0980

Alternate gene names: 218548358

Gene position: 1012826-1014028 (Clockwise)

Preceding gene: 218548356

Following gene: 218548361

Centisome position: 22.07

GC content: 50.04

Gene sequence:

>1203_bases
ATGACGCAATACTCCTCTTTCCTTCGCGGTCTCGTAGCGGGTTCTGCTCTTTTATTTCTTTTTGCCCCAACGGTTCAGGC
TGCTGAACAAGCCATTGATGCGCCCAGCGTGGATGCGCGCGCATGGGTCTTAATGGATTACGCCAGCGGGAAGGTACTGG
CAGAAGGCAACGCTGATGAAAAACTTGATCCGGCCAGCCTGACAAAAATTATGACCAGCTATGTAGTTGGTCAGGCGCTG
AAAGCCGACAAAATTAAACTGACAGATATGGTCACCGTGGGCAGAGATGCCTGGGCGACAGGAAATCCGGCGCTGCGCGG
TTCGTCGGTGATGTTCCTTAAGCCTGGCGATCAGGTGTCTGTTGCCGATCTTAATAAAGGGGTGATTATTCAGTCTGGTA
ATGATGCCTGTATTGCACTGGCCGATTATGTCGCGGGAAGTCAGGAGTCATTTATTGGGTTAATGAATGGTTATGCCAAA
AAGTTAGGATTGACCAATACTACCTTCCAGACTGTTCACGGCCTTGATGCACCGGGGCAGTTCAGTACCGCACGTGATAT
GGCGCTACTGAGCAAAGCACTTATTCATGACGTGCCAGAAGAGTATGCCATCCATAAAGAAAAAGAATTTACTTTCAATA
AGATTCGTCAGCCTAACCGCAACCGCTTGTTATGGAGCAGCAATCTCCATGTTGATGGGTTGAAAACCGGGACGACTGCC
GGGGCCGGGTATAACCTGGTGGCTTCCGCGACGCAGGGCGATATGCGTCTGATCTCAGTTGTTCTGGGCGCGAAAACTGA
TCGCATTCGTTTTAATGAGTCTGAAAAACTGCTCACCTGGGGATTCCGCTTCTTTGAAACCGTCACTCCGATAAAACCTG
ACGCAACCTTTGTCAGCCAGCGAGTCTGGTTCGGCGATAAGAGTGAAGTCAAGCTGGGGGCGGGTGAAGCCGGTTCTGTA
ACCATTCCTCGTGGGCAACTGAAAAACCTGAAAGCCAGCTTTACACTTAACGAGCCGCAGTTGACTGCTCCACTGAAAAA
AGGTCAGGTTGTTGGCACCATCGACTTCCAGTTGAATGGAAAATCTATCGAACAACGCCCACTTATCGTGATGGAAGCGG
TTGAAGAAGGGGGAATCTTTAGCCGGATGTGGGATTTCGTGATGATGAAATTCCACCAGTGGTTTGGCGGTTGGTTCTCG
TAA

Upstream 100 bases:

>100_bases
ACTTCCGGTTTTTTTAGGCTCTTGAGTGCGTTATTAATCACCGTTCTTATTGTTCGGTGATGAAACGTATATTTTTTGAA
TGGATACTCGGGTGGCATTT

Downstream 100 bases:

>100_bases
TCGGTGGACGCGCCGGAGGGTACATGAGACTATCCGGCGCAACGGGGTTAATACAGTAACCTGATATTATGCGCTTTCGC
GTACTCAATAATTTCATCAT

Product: D-alanyl-D-alanine carboxypeptidase fraction C

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTQYSSFLRGLVAGSALLFLFAPTVQAAEQAIDAPSVDARAWVLMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQAL
KADKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
KLGLTNTTFQTVHGLDAPGQFSTARDMALLSKALIHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLHVDGLKTGTTA
GAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVSQRVWFGDKSEVKLGAGEAGSV
TIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMEAVEEGGIFSRMWDFVMMKFHQWFGGWFS

Sequences:

>Translated_400_residues
MTQYSSFLRGLVAGSALLFLFAPTVQAAEQAIDAPSVDARAWVLMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQAL
KADKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
KLGLTNTTFQTVHGLDAPGQFSTARDMALLSKALIHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLHVDGLKTGTTA
GAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVSQRVWFGDKSEVKLGAGEAGSV
TIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMEAVEEGGIFSRMWDFVMMKFHQWFGGWFS
>Mature_399_residues
TQYSSFLRGLVAGSALLFLFAPTVQAAEQAIDAPSVDARAWVLMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALK
ADKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKK
LGLTNTTFQTVHGLDAPGQFSTARDMALLSKALIHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLHVDGLKTGTTAG
AGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVSQRVWFGDKSEVKLGAGEAGSVT
IPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMEAVEEGGIFSRMWDFVMMKFHQWFGGWFS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=400, Percent_Identity=94.5, Blast_Score=782, Evalue=0.0,
Organism=Escherichia coli, GI1786851, Length=362, Percent_Identity=63.2596685082873, Blast_Score=492, Evalue=1e-140,
Organism=Escherichia coli, GI87082022, Length=380, Percent_Identity=48.1578947368421, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI87082054, Length=251, Percent_Identity=26.6932270916335, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43617; Mature: 43486

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYSSFLRGLVAGSALLFLFAPTVQAAEQAIDAPSVDARAWVLMDYASGKVLAEGNADE
CCCHHHHHHHHHHHHHEEEHCCCCHHHHHHHCCCCCCCCEEEEEEEECCCEEEECCCCCC
KLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGDQVS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEE
VADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTTFQTVHGLDAPGQ
EEECCCCEEEECCCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCC
FSTARDMALLSKALIHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLHVDGLKTGTTA
CCHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHCCCCCCEEEEECCCEECCCCCCCCC
GAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVSQ
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHH
RVWFGDKSEVKLGAGEAGSVTIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNG
EEECCCCCCEEECCCCCCCEEECCHHHCCCEEEEEECCCCEECCCCCCCEEEEEEEEECC
KSIEQRPLIVMEAVEEGGIFSRMWDFVMMKFHQWFGGWFS
CCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TQYSSFLRGLVAGSALLFLFAPTVQAAEQAIDAPSVDARAWVLMDYASGKVLAEGNADE
CCHHHHHHHHHHHHHEEEHCCCCHHHHHHHCCCCCCCCEEEEEEEECCCEEEECCCCCC
KLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGDQVS
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEE
VADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTTFQTVHGLDAPGQ
EEECCCCEEEECCCCCEEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCC
FSTARDMALLSKALIHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLHVDGLKTGTTA
CCHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHCCCCCCEEEEECCCEECCCCCCCCC
GAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVSQ
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHH
RVWFGDKSEVKLGAGEAGSVTIPRGQLKNLKASFTLNEPQLTAPLKKGQVVGTIDFQLNG
EEECCCCCCEEECCCCCCCEEECCHHHCCCEEEEEECCCCEECCCCCCCEEEEEEEEECC
KSIEQRPLIVMEAVEEGGIFSRMWDFVMMKFHQWFGGWFS
CCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]