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The map label for this gene is dxs [C]

Identifier: 218548252

GI number: 218548252

Start: 883682

End: 884635

Strand: Direct

Name: dxs [C]

Synonym: EFER_0870

Alternate gene names: 218548252

Gene position: 883682-884635 (Clockwise)

Preceding gene: 218548251

Following gene: 218548256

Centisome position: 19.26

GC content: 46.65

Gene sequence:

>954_bases
ATGATTAATCTCGCACCGGCAGGACAAAAAGACAGCATCGAAATGCGCAAAATTTATGCAGGATTTATCGCGCAACAGAG
TGAAAACGGTAATTCTGTCATTGCTCTTGAGGCTGATTTAATGAGTTCCATGGCAATGGACAGCGTAGCGCGGGATTATC
CACAGCGCGTTATTAATTGCGGCATTATGGAAGCCAATGTTATCGGCACAGCTGCGGGGCTGGCCTTAACCGGGCGCAAG
CCATTCGTACATACCTTTACCGCATTTGCCAGTCGTCGCTGTTTTGATCAGCTCTTTATGTCGCTTGATTACCAGCGTGC
TAACGTAAAAGTTATCGCTTCTGATGCGGGTGTTACTGCTTGCCACAATGGCGGAACACATATGTCATTTGAAGATATGG
GGATTGTGCGCGGGCTGGCACATTCGGTGGTAATGGAGATGACCGATGCCGTAATGTTTAGCGATATTTTGCGTCAACTC
GTTGAGTTAGAAGGATTTTATTGGGTTCGTACCATCCGTAAGCAAGCAGCGAGTATTTACGCACCAGGTACGACCTTTAC
GATTGGTAAAGGACAGGTATTACGTGAAGGAACGGATATCACCTTGATTGCTAATGGCATTATGGTGGCAGAAGCGCTTG
AGGCAGCTCGTCAACTTGAGCAGGCTGGGGTAAGTGCAGCGGTCATTGATATGTTTACTCTCAAACCTATCGATCGGATG
TTAATTAAAAATTATGCCGAAAAAACAGGGCGGATCGTGACATGTGAAAACCATAGTATTCACAATGGATTAGGTTCAGC
AGTTGCTGAAGTACTTGTAGAAACTTGTCCTGTCCCCATGCGTCGGGTGGGGGTTAAAGAGCGGTATGGCCAGGTGGGAA
CTCAGGACTTTTTACAAAGGGAATATGGTTTAACGGCACATGATATTGTGGCGGCTGCGAGAGAGTTGTTGTAA

Upstream 100 bases:

>100_bases
GTACCGTGTCTTGAGCAACTCAGTAATTCCCATCATTTACGCCTCACGGAAGAGATGAAGGAGACGCTAAACGAAACAAT
TTGCCAACTGGAGGCCATGC

Downstream 100 bases:

>100_bases
CTGATTCTAAAATAAAAAATCCGGAAATAATCACTATTTCCGGATTTTGCTTTTAGTCTTTTACGCTAAACAGAAAAGAT
TACTTCTGCTGTTGTGCAGA

Product: carbohydrate degradation enzyme

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MINLAPAGQKDSIEMRKIYAGFIAQQSENGNSVIALEADLMSSMAMDSVARDYPQRVINCGIMEANVIGTAAGLALTGRK
PFVHTFTAFASRRCFDQLFMSLDYQRANVKVIASDAGVTACHNGGTHMSFEDMGIVRGLAHSVVMEMTDAVMFSDILRQL
VELEGFYWVRTIRKQAASIYAPGTTFTIGKGQVLREGTDITLIANGIMVAEALEAARQLEQAGVSAAVIDMFTLKPIDRM
LIKNYAEKTGRIVTCENHSIHNGLGSAVAEVLVETCPVPMRRVGVKERYGQVGTQDFLQREYGLTAHDIVAAARELL

Sequences:

>Translated_317_residues
MINLAPAGQKDSIEMRKIYAGFIAQQSENGNSVIALEADLMSSMAMDSVARDYPQRVINCGIMEANVIGTAAGLALTGRK
PFVHTFTAFASRRCFDQLFMSLDYQRANVKVIASDAGVTACHNGGTHMSFEDMGIVRGLAHSVVMEMTDAVMFSDILRQL
VELEGFYWVRTIRKQAASIYAPGTTFTIGKGQVLREGTDITLIANGIMVAEALEAARQLEQAGVSAAVIDMFTLKPIDRM
LIKNYAEKTGRIVTCENHSIHNGLGSAVAEVLVETCPVPMRRVGVKERYGQVGTQDFLQREYGLTAHDIVAAARELL
>Mature_317_residues
MINLAPAGQKDSIEMRKIYAGFIAQQSENGNSVIALEADLMSSMAMDSVARDYPQRVINCGIMEANVIGTAAGLALTGRK
PFVHTFTAFASRRCFDQLFMSLDYQRANVKVIASDAGVTACHNGGTHMSFEDMGIVRGLAHSVVMEMTDAVMFSDILRQL
VELEGFYWVRTIRKQAASIYAPGTTFTIGKGQVLREGTDITLIANGIMVAEALEAARQLEQAGVSAAVIDMFTLKPIDRM
LIKNYAEKTGRIVTCENHSIHNGLGSAVAEVLVETCPVPMRRVGVKERYGQVGTQDFLQREYGLTAHDIVAAARELL

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=311, Percent_Identity=31.5112540192926, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI4507521, Length=311, Percent_Identity=31.5112540192926, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI225637463, Length=311, Percent_Identity=31.8327974276527, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI225637461, Length=311, Percent_Identity=31.8327974276527, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI133778974, Length=305, Percent_Identity=32.4590163934426, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI225637459, Length=311, Percent_Identity=31.8327974276527, Blast_Score=146, Evalue=3e-35,
Organism=Escherichia coli, GI1786622, Length=309, Percent_Identity=28.4789644012945, Blast_Score=118, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17539652, Length=317, Percent_Identity=33.4384858044164, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24645119, Length=315, Percent_Identity=33.968253968254, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45551847, Length=315, Percent_Identity=33.968253968254, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45550715, Length=315, Percent_Identity=33.968253968254, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666278, Length=311, Percent_Identity=31.1897106109325, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI21358145, Length=242, Percent_Identity=27.6859504132231, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24650940, Length=242, Percent_Identity=27.6859504132231, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 34545; Mature: 34545

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLAPAGQKDSIEMRKIYAGFIAQQSENGNSVIALEADLMSSMAMDSVARDYPQRVINC
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHC
GIMEANVIGTAAGLALTGRKPFVHTFTAFASRRCFDQLFMSLDYQRANVKVIASDAGVTA
CCEECHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEE
CHNGGTHMSFEDMGIVRGLAHSVVMEMTDAVMFSDILRQLVELEGFYWVRTIRKQAASIY
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEE
APGTTFTIGKGQVLREGTDITLIANGIMVAEALEAARQLEQAGVSAAVIDMFTLKPIDRM
CCCCEEEECCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LIKNYAEKTGRIVTCENHSIHNGLGSAVAEVLVETCPVPMRRVGVKERYGQVGTQDFLQR
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHCCCCHHHHHHH
EYGLTAHDIVAAARELL
HHCCCHHHHHHHHHHHC
>Mature Secondary Structure
MINLAPAGQKDSIEMRKIYAGFIAQQSENGNSVIALEADLMSSMAMDSVARDYPQRVINC
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHC
GIMEANVIGTAAGLALTGRKPFVHTFTAFASRRCFDQLFMSLDYQRANVKVIASDAGVTA
CCEECHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEE
CHNGGTHMSFEDMGIVRGLAHSVVMEMTDAVMFSDILRQLVELEGFYWVRTIRKQAASIY
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEE
APGTTFTIGKGQVLREGTDITLIANGIMVAEALEAARQLEQAGVSAAVIDMFTLKPIDRM
CCCCEEEECCCCEEECCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LIKNYAEKTGRIVTCENHSIHNGLGSAVAEVLVETCPVPMRRVGVKERYGQVGTQDFLQR
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHCCCCHHHHHHH
EYGLTAHDIVAAARELL
HHCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]