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The map label for this gene is tktA [C]

Identifier: 218548251

GI number: 218548251

Start: 882859

End: 883689

Strand: Direct

Name: tktA [C]

Synonym: EFER_0869

Alternate gene names: 218548251

Gene position: 882859-883689 (Clockwise)

Preceding gene: 218548250

Following gene: 218548252

Centisome position: 19.24

GC content: 47.89

Gene sequence:

>831_bases
ATGAATGTTAAAGAAGTGACGCAATTTGCACGGGATATACGTATCCAGACGCTGAAATCATTAACCCATCTTGGCTTCGG
TCATTATGGTGGCAGCATGTCGGTTGTGGAAACGCTAGCGGTGCTTTATGGCGCGGTAATGAAAATTGATCCTGCTGATC
CCGACTGGCCTGAGCGTGACTATTTTGTCTTGTCAAAAGGACATGCCGGACCTGCGCTCTACAGTACTCTGGCGTTGAAA
GGTTATTTTCCACTGGAAGAATTAAGCACCTTAAATCAGAACGGCACTCGCTTACCAAGTCATCCGGATCGGCTAAAGAC
GCGTGGTGTTGATGCCACTACAGGATCGCTGGGGCAGGGGATATCCATTGCCGGGGGGATGGCGCTGTCGCATAAACTGG
CGGGGCGCAAGAATCGGGTATTTTGTATTGTTGGCGATGGAGAACTTAATGAAGGTCAGTGTTGGGAAGCCTTCCAGTTT
ATCGCGCATCATCGGTTGAATAATCTCACTGTTTTTGTGGACTGGAACAAACAGCAGCTTGATGGTCAACTGGACGAAAT
CATTAATCCGTTTGATTTAGAAAGTAAATTCCGCGCTTTCGGTTTTGATGTCGTGACAGTGAAGGGCGATGATATTGAGG
GCTTGTTGAATGTAGTTAAACCTGTCCCGCCAGCTGAGGCCAGACCGAGAGTGGTCATTCTCGATAGCATTAAAGGGCAG
GGTGTACCGTGTCTTGAGCAACTCAGTAATTCCCATCATTTACGCCTCACGGAAGAGATGAAGGAGACGCTAAACGAAAC
AATTTGCCAACTGGAGGCCATGCATGATTAA

Upstream 100 bases:

>100_bases
CCGGACTTGTAGTCGCAGTATTTGTACTGCTGGTTGCCTGGAACATTTTCGCCAATAACAAACTCGCTGCCAAAGCGCAG
GAGAAGAGCGGAGCCAAATC

Downstream 100 bases:

>100_bases
TCTCGCACCGGCAGGACAAAAAGACAGCATCGAAATGCGCAAAATTTATGCAGGATTTATCGCGCAACAGAGTGAAAACG
GTAATTCTGTCATTGCTCTT

Product: carbohydrate degradation enzyme

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNVKEVTQFARDIRIQTLKSLTHLGFGHYGGSMSVVETLAVLYGAVMKIDPADPDWPERDYFVLSKGHAGPALYSTLALK
GYFPLEELSTLNQNGTRLPSHPDRLKTRGVDATTGSLGQGISIAGGMALSHKLAGRKNRVFCIVGDGELNEGQCWEAFQF
IAHHRLNNLTVFVDWNKQQLDGQLDEIINPFDLESKFRAFGFDVVTVKGDDIEGLLNVVKPVPPAEARPRVVILDSIKGQ
GVPCLEQLSNSHHLRLTEEMKETLNETICQLEAMHD

Sequences:

>Translated_276_residues
MNVKEVTQFARDIRIQTLKSLTHLGFGHYGGSMSVVETLAVLYGAVMKIDPADPDWPERDYFVLSKGHAGPALYSTLALK
GYFPLEELSTLNQNGTRLPSHPDRLKTRGVDATTGSLGQGISIAGGMALSHKLAGRKNRVFCIVGDGELNEGQCWEAFQF
IAHHRLNNLTVFVDWNKQQLDGQLDEIINPFDLESKFRAFGFDVVTVKGDDIEGLLNVVKPVPPAEARPRVVILDSIKGQ
GVPCLEQLSNSHHLRLTEEMKETLNETICQLEAMHD
>Mature_276_residues
MNVKEVTQFARDIRIQTLKSLTHLGFGHYGGSMSVVETLAVLYGAVMKIDPADPDWPERDYFVLSKGHAGPALYSTLALK
GYFPLEELSTLNQNGTRLPSHPDRLKTRGVDATTGSLGQGISIAGGMALSHKLAGRKNRVFCIVGDGELNEGQCWEAFQF
IAHHRLNNLTVFVDWNKQQLDGQLDEIINPFDLESKFRAFGFDVVTVKGDDIEGLLNVVKPVPPAEARPRVVILDSIKGQ
GVPCLEQLSNSHHLRLTEEMKETLNETICQLEAMHD

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=263, Percent_Identity=35.361216730038, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI4507521, Length=263, Percent_Identity=35.361216730038, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI133778974, Length=261, Percent_Identity=32.9501915708812, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI225637459, Length=263, Percent_Identity=27.7566539923954, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI225637461, Length=235, Percent_Identity=28.5106382978723, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI225637463, Length=233, Percent_Identity=28.3261802575107, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI48994911, Length=257, Percent_Identity=32.295719844358, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1788808, Length=263, Percent_Identity=31.5589353612167, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17539652, Length=248, Percent_Identity=35.0806451612903, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6325331, Length=246, Percent_Identity=34.1463414634146, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319593, Length=242, Percent_Identity=31.8181818181818, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI45551847, Length=265, Percent_Identity=32.0754716981132, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45550715, Length=265, Percent_Identity=32.0754716981132, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666278, Length=255, Percent_Identity=35.6862745098039, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24645119, Length=229, Percent_Identity=33.6244541484716, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30549; Mature: 30549

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKEVTQFARDIRIQTLKSLTHLGFGHYGGSMSVVETLAVLYGAVMKIDPADPDWPERD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCC
YFVLSKGHAGPALYSTLALKGYFPLEELSTLNQNGTRLPSHPDRLKTRGVDATTGSLGQG
EEEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCC
ISIAGGMALSHKLAGRKNRVFCIVGDGELNEGQCWEAFQFIAHHRLNNLTVFVDWNKQQL
CEECCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHH
DGQLDEIINPFDLESKFRAFGFDVVTVKGDDIEGLLNVVKPVPPAEARPRVVILDSIKGQ
CCCHHHHCCCCCCCHHHHHHCEEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEECCCCC
GVPCLEQLSNSHHLRLTEEMKETLNETICQLEAMHD
CCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVKEVTQFARDIRIQTLKSLTHLGFGHYGGSMSVVETLAVLYGAVMKIDPADPDWPERD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCC
YFVLSKGHAGPALYSTLALKGYFPLEELSTLNQNGTRLPSHPDRLKTRGVDATTGSLGQG
EEEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCC
ISIAGGMALSHKLAGRKNRVFCIVGDGELNEGQCWEAFQFIAHHRLNNLTVFVDWNKQQL
CEECCCHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHH
DGQLDEIINPFDLESKFRAFGFDVVTVKGDDIEGLLNVVKPVPPAEARPRVVILDSIKGQ
CCCHHHHCCCCCCCHHHHHHCEEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEECCCCC
GVPCLEQLSNSHHLRLTEEMKETLNETICQLEAMHD
CCHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]