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The map label for this gene is aegA [H]

Identifier: 218548099

GI number: 218548099

Start: 728567

End: 730675

Strand: Direct

Name: aegA [H]

Synonym: EFER_0711

Alternate gene names: 218548099

Gene position: 728567-730675 (Clockwise)

Preceding gene: 218548093

Following gene: 218548100

Centisome position: 15.88

GC content: 51.02

Gene sequence:

>2109_bases
TTGATCTGCCACATGTTCAGTCGAAATAGTTGGGCTTTATGGGCAGATGAACATTGCCGACGCGCATTTTTGTCGGTAAT
AACAGGCGTGCAAAGAATAAGGTTTTTACAACCAAAAAAGAAGGTCGCCATGAATCGATTTATTACGGCCAATAGCCAGC
AGTGCCTGGGCTGTCATGCCTGCGAAGTGGCCTGCGTAATGGCTCACAATGATGAGCAACATGTGTTGAGTCAGCAACAT
TTTCACCCAAGGATTACGGTTATTAAACATCAGCATTTGAACAGTGCGGTCACTTGCCATCACTGTGAAGATGCGCCTTG
CGCCCGCAGCTGTCCGAACGGAGCTATCAGCCACGTCAATGACAGTGTTCAGGTTAATCAGCAAAAATGTATTGGCTGCA
AATCCTGTGTTATTGCCTGCCCGTTCGGCACGATGCAAATTGTATTGTCACCTGTTTCAGCAGAGCGGGTAAAAGCTACG
GCGCATAAATGCGATCTGTGTGAAGGGCGTGAAAACGGTCCCGCCTGTGTGGAAAACTGCCCGGCAGATGCACTGCAACT
GGTTACTGAAGCCGCGTTAACCGGGTTGGCGAAAAATCGCAGGCTGCGAACGGCACGGCAAGAAAATCAATCCTGGCACG
ACGGCTTAGAGCAGGAACGCCCGCTCACCTTTAGTAAAGTTGAGCAGATGCGTGCCACTCCACCACGTGGTGAACCGGAC
AAACTGCCCATTGCCGCGCGTAAAACCGGGTTTGATGAAATCTATCTGCCGTTTCGTGCTCAACAGGCACACCAGGAAGC
TTCCCGTTGCCTTAAGTGCGGCGAACACAGCGTGTGTGAGTGGACTTGCCCACTGCATAACCATATTCCCCAGTGGATCG
AACTGGTTAAAGCCGGAAATATAGATGCCGCCGTCGAGCTGTCTCACCAGACTAATACGCTGCCAGAAATTACCGGGCGC
GTTTGTCCGCAAGACCGGCTATGTGAAGGGGCTTGTACTATTCGTGATGAACATGGTGCAGTCACTATCGGAAACATTGA
ACGTTACATTTCAGACCAGGCACTGGCAAAAGGATGGCGCCCCGATCTCAGTGGTGTCAGCAAAGTCGGTAAACGTGTGG
CGATTATTGGTGCAGGACCGGCAGGGCTTGCCTGTGCCGATGTGCTGACACGCAACGGTATTGATACCACGGTGTTTGAT
CGTCACCCGGAAATTGGTGGCTTACTTACTTTTGGTATTCCCTCCTTTAAGCTGGATAAATCGCTGCTTGCGCGGCGTCG
TGAAATCTTCAGTGCAATGGGAATCGACTTTAGGCTCAATTGTGAAATTGGCAAAGATGTGATGCTGGAAACGTTGCTGG
AGGAGTACGACGCAGTATTTGTTGGCGTTGGCACTTACCGCTCGATGAAGGCGAACTTACCGAATGAAGACGCGCCGGGG
GTATACGATGCGTTACCGTTCCTGATAGCCAATACCAAACAAGTGATGGGGCTACCAGAATTGCCAGAAGAGCCGTTTAT
CAATACTGCCGGGCTGAATGTTGTGGTGCTTGGTGGTGGCGATACAGCGATGGACTGCGTCCGTACGGCGCTACGTCATG
GTGCGAGTAATGTCACCTGTGCGTATCGTCGTGATGAAGCTAACATGCCGGGATCGAAGAAAGAGGTGAAAAACGCCCGC
GACGAAGGGGCTAATTTCGAATTTAACGTCCAGCCGATTGAGATTGAACTTAATTCACAAGGGCATGTATGTGGGATTCG
TTTTTTACGCACTCGTCTTGGTGAACCTGACGCAAATGGTCGTCGTCGCCCGGTGCCTGTCGAAGGTAGTGAGTTCGTTA
TGCCTGCAGATGCGGTTATTATGGCGTTTGGCTTTAATCCTCATACAATGCCGTGGCTGGAAGCGCATTCAGTGAAAGTG
GATGACTGGGGGCGGATTGCTGCAAATGTGAACAGTAAATACCGTTACCAGACCAGTAACCCGAAAATCTTTGCTGGTGG
CGATGCTGTACGCGGTGCTGATCTGGTGGTAACAGCAATGGCGGAAGGACGCCATGCTGCACAGGGCATTGTCGACTGGC
TGGGCGTAAAATCAGTCAAATCTCACTAA

Upstream 100 bases:

>100_bases
TAACGATCACTCGCATTTTCTCCGCGAAACAGGGTCAATATGAAATTAAACAAAGCGTTTCAGATAATTACATCCAAAAT
AATATCAGCTGTGTAATAAA

Downstream 100 bases:

>100_bases
CGCACTACGCAGACAAACCCAACTTCGCGGCGTAAGATGATGAGTCTTCTTATGCCGTGGAGCTGGTATGTCACAACAAA
TTACCCTCATCAAAGATAAA

Product: oxidoreductase Fe-S binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 702

Protein sequence:

>702_residues
MICHMFSRNSWALWADEHCRRAFLSVITGVQRIRFLQPKKKVAMNRFITANSQQCLGCHACEVACVMAHNDEQHVLSQQH
FHPRITVIKHQHLNSAVTCHHCEDAPCARSCPNGAISHVNDSVQVNQQKCIGCKSCVIACPFGTMQIVLSPVSAERVKAT
AHKCDLCEGRENGPACVENCPADALQLVTEAALTGLAKNRRLRTARQENQSWHDGLEQERPLTFSKVEQMRATPPRGEPD
KLPIAARKTGFDEIYLPFRAQQAHQEASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITGR
VCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSGVSKVGKRVAIIGAGPAGLACADVLTRNGIDTTVFD
RHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGIDFRLNCEIGKDVMLETLLEEYDAVFVGVGTYRSMKANLPNEDAPG
VYDALPFLIANTKQVMGLPELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPGSKKEVKNAR
DEGANFEFNVQPIEIELNSQGHVCGIRFLRTRLGEPDANGRRRPVPVEGSEFVMPADAVIMAFGFNPHTMPWLEAHSVKV
DDWGRIAANVNSKYRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGIVDWLGVKSVKSH

Sequences:

>Translated_702_residues
MICHMFSRNSWALWADEHCRRAFLSVITGVQRIRFLQPKKKVAMNRFITANSQQCLGCHACEVACVMAHNDEQHVLSQQH
FHPRITVIKHQHLNSAVTCHHCEDAPCARSCPNGAISHVNDSVQVNQQKCIGCKSCVIACPFGTMQIVLSPVSAERVKAT
AHKCDLCEGRENGPACVENCPADALQLVTEAALTGLAKNRRLRTARQENQSWHDGLEQERPLTFSKVEQMRATPPRGEPD
KLPIAARKTGFDEIYLPFRAQQAHQEASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITGR
VCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSGVSKVGKRVAIIGAGPAGLACADVLTRNGIDTTVFD
RHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGIDFRLNCEIGKDVMLETLLEEYDAVFVGVGTYRSMKANLPNEDAPG
VYDALPFLIANTKQVMGLPELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPGSKKEVKNAR
DEGANFEFNVQPIEIELNSQGHVCGIRFLRTRLGEPDANGRRRPVPVEGSEFVMPADAVIMAFGFNPHTMPWLEAHSVKV
DDWGRIAANVNSKYRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGIVDWLGVKSVKSH
>Mature_702_residues
MICHMFSRNSWALWADEHCRRAFLSVITGVQRIRFLQPKKKVAMNRFITANSQQCLGCHACEVACVMAHNDEQHVLSQQH
FHPRITVIKHQHLNSAVTCHHCEDAPCARSCPNGAISHVNDSVQVNQQKCIGCKSCVIACPFGTMQIVLSPVSAERVKAT
AHKCDLCEGRENGPACVENCPADALQLVTEAALTGLAKNRRLRTARQENQSWHDGLEQERPLTFSKVEQMRATPPRGEPD
KLPIAARKTGFDEIYLPFRAQQAHQEASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITGR
VCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSGVSKVGKRVAIIGAGPAGLACADVLTRNGIDTTVFD
RHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGIDFRLNCEIGKDVMLETLLEEYDAVFVGVGTYRSMKANLPNEDAPG
VYDALPFLIANTKQVMGLPELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPGSKKEVKNAR
DEGANFEFNVQPIEIELNSQGHVCGIRFLRTRLGEPDANGRRRPVPVEGSEFVMPADAVIMAFGFNPHTMPWLEAHSVKV
DDWGRIAANVNSKYRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGIVDWLGVKSVKSH

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=477, Percent_Identity=29.559748427673, Blast_Score=164, Evalue=2e-40,
Organism=Escherichia coli, GI1788811, Length=659, Percent_Identity=89.0743550834598, Blast_Score=1235, Evalue=0.0,
Organism=Escherichia coli, GI87082180, Length=656, Percent_Identity=54.2682926829268, Blast_Score=734, Evalue=0.0,
Organism=Escherichia coli, GI1789606, Length=461, Percent_Identity=67.0281995661605, Blast_Score=656, Evalue=0.0,
Organism=Escherichia coli, GI1788468, Length=446, Percent_Identity=31.1659192825112, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1789067, Length=172, Percent_Identity=48.8372093023256, Blast_Score=163, Evalue=4e-41,
Organism=Escherichia coli, GI1789243, Length=433, Percent_Identity=33.0254041570439, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI2367245, Length=147, Percent_Identity=53.7414965986395, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87082179, Length=165, Percent_Identity=46.6666666666667, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1789079, Length=185, Percent_Identity=39.4594594594595, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI87082114, Length=213, Percent_Identity=34.7417840375587, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787122, Length=155, Percent_Identity=32.9032258064516, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787872, Length=152, Percent_Identity=32.8947368421053, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790326, Length=184, Percent_Identity=28.804347826087, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787749, Length=203, Percent_Identity=26.1083743842365, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI2367345, Length=148, Percent_Identity=33.1081081081081, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17570289, Length=477, Percent_Identity=33.1236897274633, Blast_Score=212, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI71984108, Length=446, Percent_Identity=31.6143497757848, Blast_Score=159, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17543860, Length=161, Percent_Identity=31.055900621118, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320030, Length=470, Percent_Identity=33.4042553191489, Blast_Score=221, Evalue=3e-58,
Organism=Drosophila melanogaster, GI28574881, Length=473, Percent_Identity=37.4207188160677, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI24665539, Length=473, Percent_Identity=37.4207188160677, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI24665547, Length=473, Percent_Identity=37.4207188160677, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24665543, Length=473, Percent_Identity=37.4207188160677, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24640763, Length=452, Percent_Identity=29.2035398230088, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI18858217, Length=452, Percent_Identity=29.2035398230088, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 77189; Mature: 77189

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICHMFSRNSWALWADEHCRRAFLSVITGVQRIRFLQPKKKVAMNRFITANSQQCLGCHA
CEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCHH
CEVACVMAHNDEQHVLSQQHFHPRITVIKHQHLNSAVTCHHCEDAPCARSCPNGAISHVN
HEEEEEEECCCHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCHHHCCCCCCHHHCC
DSVQVNQQKCIGCKSCVIACPFGTMQIVLSPVSAERVKATAHKCDLCEGRENGPACVENC
CCEEECHHHHCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHCC
PADALQLVTEAALTGLAKNRRLRTARQENQSWHDGLEQERPLTFSKVEQMRATPPRGEPD
CHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCCC
KLPIAARKTGFDEIYLPFRAQQAHQEASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGN
CCCEECCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCHHHHHHHHCCC
IDAAVELSHQTNTLPEITGRVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWR
CCEEEEECCCCCCCHHHHCCCCCHHHHCCCCCEEEECCCEEEECCHHHHHHHHHHHCCCC
PDLSGVSKVGKRVAIIGAGPAGLACADVLTRNGIDTTVFDRHPEIGGLLTFGIPSFKLDK
CCHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCHHHHH
SLLARRREIFSAMGIDFRLNCEIGKDVMLETLLEEYDAVFVGVGTYRSMKANLPNEDAPG
HHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCEEEEECCCCHHHCCCCCCCCCCC
VYDALPFLIANTKQVMGLPELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTC
HHHHHHHHHCCCHHHCCCCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEE
AYRRDEANMPGSKKEVKNARDEGANFEFNVQPIEIELNSQGHVCGIRFLRTRLGEPDANG
EEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCC
RRRPVPVEGSEFVMPADAVIMAFGFNPHTMPWLEAHSVKVDDWGRIAANVNSKYRYQTSN
CCCCCCCCCCCEEECCCEEEEEECCCCCCCCCEECCEEEECCCCCEEECCCCCEEEECCC
PKIFAGGDAVRGADLVVTAMAEGRHAAQGIVDWLGVKSVKSH
CEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MICHMFSRNSWALWADEHCRRAFLSVITGVQRIRFLQPKKKVAMNRFITANSQQCLGCHA
CEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCHH
CEVACVMAHNDEQHVLSQQHFHPRITVIKHQHLNSAVTCHHCEDAPCARSCPNGAISHVN
HEEEEEEECCCHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCHHHCCCCCCHHHCC
DSVQVNQQKCIGCKSCVIACPFGTMQIVLSPVSAERVKATAHKCDLCEGRENGPACVENC
CCEEECHHHHCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHCC
PADALQLVTEAALTGLAKNRRLRTARQENQSWHDGLEQERPLTFSKVEQMRATPPRGEPD
CHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCCC
KLPIAARKTGFDEIYLPFRAQQAHQEASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGN
CCCEECCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCHHHHHHHHCCC
IDAAVELSHQTNTLPEITGRVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWR
CCEEEEECCCCCCCHHHHCCCCCHHHHCCCCCEEEECCCEEEECCHHHHHHHHHHHCCCC
PDLSGVSKVGKRVAIIGAGPAGLACADVLTRNGIDTTVFDRHPEIGGLLTFGIPSFKLDK
CCHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCCCEEEECCCCHHHHH
SLLARRREIFSAMGIDFRLNCEIGKDVMLETLLEEYDAVFVGVGTYRSMKANLPNEDAPG
HHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCEEEEECCCCHHHCCCCCCCCCCC
VYDALPFLIANTKQVMGLPELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTC
HHHHHHHHHCCCHHHCCCCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEE
AYRRDEANMPGSKKEVKNARDEGANFEFNVQPIEIELNSQGHVCGIRFLRTRLGEPDANG
EEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCC
RRRPVPVEGSEFVMPADAVIMAFGFNPHTMPWLEAHSVKVDDWGRIAANVNSKYRYQTSN
CCCCCCCCCCCEEECCCEEEEEECCCCCCCCCEECCEEEECCCCCEEECCCCCEEEECCC
PKIFAGGDAVRGADLVVTAMAEGRHAAQGIVDWLGVKSVKSH
CEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]