Click here to switch to the map view.

The map label for this gene is cdsA [H]

Identifier: 218547630

GI number: 218547630

Start: 217162

End: 218019

Strand: Direct

Name: cdsA [H]

Synonym: EFER_0197

Alternate gene names: 218547630

Gene position: 217162-218019 (Clockwise)

Preceding gene: 218547629

Following gene: 218547631

Centisome position: 4.73

GC content: 49.42

Gene sequence:

>858_bases
TTGCTGAAGTATCGCCTGATTTCTGCTTTTGTTTTAATACCTGTAGTCATCGCGGCATTGTTTCTGTTGCCGCCGGTGGG
GTTCGCCATTGTTACGCTGGTGGTTTGTATGCTGGCAGCGTGGGAATGGGGACAGCTTAGCGGTTTTACCTCTCGCTCGC
AGCGGGTATGGTTGGCGGTGCTATGCGGGTTATTGCTGGCGCTAATGCTATTTCTGTTGCCTGACTATAACCGCAGTATT
CAACATTCACTGGTTGCGGTTTCGCTTTGGGCCTCAACAGGATGGTGGATCGCTGCGCTATTGCTGGTACTGTTTTATCC
TGGATCAGCTGCAATCTGGCGTAATTCAAAAACATTACGCATTATCTTCGGCATTCTGACCATTGTTCCTTTCTTCTGGG
GAATGTTGGCGTTACGCAGCTGGCACTATGACGAGAACCATTACAGTGGCGCGATATGGCTGCTGTATGTCATGATCCTC
GTATGGGGAGCTGACTCTGGCGCATATATGTTTGGTAAATTATTTGGTAAACATAAGCTGGCCCCGAAGGTCTCTCCCGG
TAAAACCTGGCAGGGTTTTATTGGTGGACTGGCAACTGCCGCAGTAATCTCCTGGGGCTACAGCATGTGGGCTGATCTCA
ATGTTGCGCCAGTAATTTTACTTGTATGCTCTATCGTCGCGGCATTGGCTTCGGTATTGGGCGATTTAACCGAGAGTATG
TTTAAGCGTGAAGCCGGAATCAAAGACAGTGGTCATCTGATTCCTGGCCATGGTGGTATTCTGGATCGTATTGATAGCCT
GACCGCTGCTGTGCCGGTCTTTGCTTGCCTGTTGTTACTGGTATTCAGGACGCTTTAA

Upstream 100 bases:

>100_bases
TGAACAAGACTTTGAAGGGGCACTAAATGCCTTTGCCAATCGAGAGCGTCGTTTCGGCGGCACCGAGCCCGGTGATGAAA
CAGCCTGATGGGGGTCGCTT

Downstream 100 bases:

>100_bases
CGGAAGGTATTATGCTGAGTGTTCTCTGGGATTTGGCTTCATTCATCGTTGCGCTGGGTGTACTTATCACGGTGCATGAA
TTTGGTCATTTCTGGGTTGC

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWGQLSGFTSRSQRVWLAVLCGLLLALMLFLLPDYNRSI
QHSLVAVSLWASTGWWIAALLLVLFYPGSAAIWRNSKTLRIIFGILTIVPFFWGMLALRSWHYDENHYSGAIWLLYVMIL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYSMWADLNVAPVILLVCSIVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL

Sequences:

>Translated_285_residues
MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWGQLSGFTSRSQRVWLAVLCGLLLALMLFLLPDYNRSI
QHSLVAVSLWASTGWWIAALLLVLFYPGSAAIWRNSKTLRIIFGILTIVPFFWGMLALRSWHYDENHYSGAIWLLYVMIL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYSMWADLNVAPVILLVCSIVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL
>Mature_285_residues
MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWGQLSGFTSRSQRVWLAVLCGLLLALMLFLLPDYNRSI
QHSLVAVSLWASTGWWIAALLLVLFYPGSAAIWRNSKTLRIIFGILTIVPFFWGMLALRSWHYDENHYSGAIWLLYVMIL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYSMWADLNVAPVILLVCSIVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=285, Percent_Identity=93.3333333333333, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1787677, Length=117, Percent_Identity=44.4444444444444, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31312; Mature: 31312

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]