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The map label for this gene is dgt [H]

Identifier: 218547616

GI number: 218547616

Start: 200961

End: 202478

Strand: Direct

Name: dgt [H]

Synonym: EFER_0183

Alternate gene names: 218547616

Gene position: 200961-202478 (Clockwise)

Preceding gene: 218547612

Following gene: 218547617

Centisome position: 4.38

GC content: 45.45

Gene sequence:

>1518_bases
ATGATTCAGATTGATTTCCGAAAAAAAATAAACTGGCATCGTCGTTATCGTTCGCCTCAAGGGGTGAAAACCGAGCATGA
AATTTTGCGGATCTTTGAAAGTGATCGCGGGCGGATTATTAACTCGCCAGCCATTCGCCGTCTGCAACAAAAAACCCAGG
TCTTCCCACTGGAGCGCAACGCTGCGGTGCGCACACGTCTTACTCATTCTCTGGAAGTCCAACAAGTTGGGCGGTATATC
GCCAAAGAGATATTAAGCCGCCTGAAAGAGCAAGACCTGCTGAAGACCTACGGTCTTGATGAACTGACAGGTCCATTTGA
AAGTATCGTGGAGATGTCTTGCCTGATGCATGACATTGGCAACCCTCCGTTTGGTCACTTTGGTGAGGCGGCAATTAATG
ACTGGTTTCGCCAGCGCCTGTTTCCGGCAGATGCAGAAAGCCAACCGCTTAGCGATGACCGCTGTATTGTCGCATTACTG
CGTTTGCGGGAAGGAGAAGAGACGTTAAACGAGCTGCGGCGTAAGGTGCGTCAGGATCTTTGCCACTTTGAAGGTAATGC
ACAAGGTATTCGCCTGGTGCATACATTGATGCGGATGAATCTCACCTGGGCACAAGTTGGCGGTATATTAAAATACACGC
GCCCGGCGTGGTGGCGCGGTCAACCACCAGCGACTCATCACTATTTAATGAAAAAACCGGGCTACTATCTTTCTGAAGAA
CCCTATATTGCGAGATTACGTAAAGAACTTAATTTAGCGCTTTACAGTCGTTTTCCATTAACCTGGATTATGGAGGCTGC
CGATGATATCTCCTATTGTGTGGCTGATCTGGAAGATGCGGTAGAAAAAAACATTTTCAGCGTCGAGCAACTTTATCATC
ACTTGCATGAAGCGTGGGGAGAACACGAAAAAGGTTCTCTCTTTGCTCAGGTGGTAGAAAACGCCTGGGAAAAATCGCAC
GTGAATTCTCTTAGTCGCAGTACAGAAGATCAGTTTTTTATGTATTTACGGGTAAACACCTTAAATAAACTGGTGCCGCA
TGCGGCGCAGCGTTTTATTGATAATTTGGCGGAGATTTTTGAAGGAACGTTTAATCACGCCCTGTTGGAAGATAATAGTA
GTTATAGCCGATTGCTGGAGCTTTATAAAAATGTGGCGCAAAAACATGTTTTTAGCCATCCAGAGGTCGAGCAGTTAGAA
TTACAAGGGTATCGGGTAATTAGCGGATTATTAGAAATTTATCGCCCGCTATTAAGCTTACCTTTATCCGATTTTGCCGA
ATTGGTAGAAAAAGAAAGGTTGAAGCGTTTTCCTATAGAGTCTCGCTTATTTCAGAAGCTCTCAACCCGTCATCGCCTTG
CATATGTCGAAGCTGTTGGTAAATTATCGTCTGACTCGCCAGAATATCCGATACTGGAATATTATTATCGTTGCCGATTG
CTGCAGGATTATATCAGCGGTATGACAGATCTTTATGCATGGGATGAGTACCGGCGTCTGATGGCCGTAGAACAATAA

Upstream 100 bases:

>100_bases
AATAATACCGATTTTCATAAAGATACTCGCGCCAGGTCAGATTTAAAGGCATAGTTTATCATGCGCTTGTAAGGAAGCGT
AATGCTCAGCGGGAGAGGAC

Downstream 100 bases:

>100_bases
CCAGGCTTTTGTAAAGACGGACAATAAATTTTTACTTTTTGCAGAAACTTTAGTTCGGAACTTCGCGCTATAAAACGAAT
CTGAGGAACACAGCAATTTT

Product: deoxyguanosinetriphosphate triphosphohydrolase

Products: NA

Alternate protein names: dGTP triphosphohydrolase; dGTPase [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MIQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSLEVQQVGRYI
AKEILSRLKEQDLLKTYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLFPADAESQPLSDDRCIVALL
RLREGEETLNELRRKVRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGQPPATHHYLMKKPGYYLSEE
PYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKNIFSVEQLYHHLHEAWGEHEKGSLFAQVVENAWEKSH
VNSLSRSTEDQFFMYLRVNTLNKLVPHAAQRFIDNLAEIFEGTFNHALLEDNSSYSRLLELYKNVAQKHVFSHPEVEQLE
LQGYRVISGLLEIYRPLLSLPLSDFAELVEKERLKRFPIESRLFQKLSTRHRLAYVEAVGKLSSDSPEYPILEYYYRCRL
LQDYISGMTDLYAWDEYRRLMAVEQ

Sequences:

>Translated_505_residues
MIQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSLEVQQVGRYI
AKEILSRLKEQDLLKTYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLFPADAESQPLSDDRCIVALL
RLREGEETLNELRRKVRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGQPPATHHYLMKKPGYYLSEE
PYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKNIFSVEQLYHHLHEAWGEHEKGSLFAQVVENAWEKSH
VNSLSRSTEDQFFMYLRVNTLNKLVPHAAQRFIDNLAEIFEGTFNHALLEDNSSYSRLLELYKNVAQKHVFSHPEVEQLE
LQGYRVISGLLEIYRPLLSLPLSDFAELVEKERLKRFPIESRLFQKLSTRHRLAYVEAVGKLSSDSPEYPILEYYYRCRL
LQDYISGMTDLYAWDEYRRLMAVEQ
>Mature_505_residues
MIQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSLEVQQVGRYI
AKEILSRLKEQDLLKTYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLFPADAESQPLSDDRCIVALL
RLREGEETLNELRRKVRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGQPPATHHYLMKKPGYYLSEE
PYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKNIFSVEQLYHHLHEAWGEHEKGSLFAQVVENAWEKSH
VNSLSRSTEDQFFMYLRVNTLNKLVPHAAQRFIDNLAEIFEGTFNHALLEDNSSYSRLLELYKNVAQKHVFSHPEVEQLE
LQGYRVISGLLEIYRPLLSLPLSDFAELVEKERLKRFPIESRLFQKLSTRHRLAYVEAVGKLSSDSPEYPILEYYYRCRL
LQDYISGMTDLYAWDEYRRLMAVEQ

Specific function: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs [H]

COG id: COG0232

COG function: function code F; dGTP triphosphohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dGTPase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786355, Length=505, Percent_Identity=90.8910891089109, Blast_Score=949, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006261
- InterPro:   IPR020779
- InterPro:   IPR003607 [H]

Pfam domain/function: NA

EC number: =3.1.5.1 [H]

Molecular weight: Translated: 59419; Mature: 59419

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERN
CEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCCCC
AAVRTRLTHSLEVQQVGRYIAKEILSRLKEQDLLKTYGLDELTGPFESIVEMSCLMHDIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCC
NPPFGHFGEAAINDWFRQRLFPADAESQPLSDDRCIVALLRLREGEETLNELRRKVRQDL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
CHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGQPPATHHYLMKKPGYYLSEE
HHCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCC
PYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKNIFSVEQLYHHLHEAWG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EHEKGSLFAQVVENAWEKSHVNSLSRSTEDQFFMYLRVNTLNKLVPHAAQRFIDNLAEIF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
EGTFNHALLEDNSSYSRLLELYKNVAQKHVFSHPEVEQLELQGYRVISGLLEIYRPLLSL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PLSDFAELVEKERLKRFPIESRLFQKLSTRHRLAYVEAVGKLSSDSPEYPILEYYYRCRL
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LQDYISGMTDLYAWDEYRRLMAVEQ
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERN
CEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCCCC
AAVRTRLTHSLEVQQVGRYIAKEILSRLKEQDLLKTYGLDELTGPFESIVEMSCLMHDIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCC
NPPFGHFGEAAINDWFRQRLFPADAESQPLSDDRCIVALLRLREGEETLNELRRKVRQDL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
CHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGQPPATHHYLMKKPGYYLSEE
HHCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCC
PYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKNIFSVEQLYHHLHEAWG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EHEKGSLFAQVVENAWEKSHVNSLSRSTEDQFFMYLRVNTLNKLVPHAAQRFIDNLAEIF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
EGTFNHALLEDNSSYSRLLELYKNVAQKHVFSHPEVEQLELQGYRVISGLLEIYRPLLSL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PLSDFAELVEKERLKRFPIESRLFQKLSTRHRLAYVEAVGKLSSDSPEYPILEYYYRCRL
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LQDYISGMTDLYAWDEYRRLMAVEQ
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8995266 [H]