Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 218236009

GI number: 218236009

Start: 1776596

End: 1777294

Strand: Direct

Name: ycbL [H]

Synonym: BCB4264_A1869

Alternate gene names: 218236009

Gene position: 1776596-1777294 (Clockwise)

Preceding gene: 218231654

Following gene: 218235425

Centisome position: 32.78

GC content: 30.19

Gene sequence:

>699_bases
ATGGAAAAAAATTCGATATTAATTGTAGATGACGATAAAGATATTATTCAATTTATTAATGTGAATTTAAAACAAGAAGG
TTTTAAAGTTTTTAGTGCTCATAACGGAGAAGAGGCTTTAGAAATAATAAATAATAACAGTATTCAACTTGCTATTTTGG
ATATTATGATGCCTCAAATGGATGGTATAGAACTTTGTAGAAGGATTAGAGAGAAACATAGTTTACCAATTATGTTTTTA
AGCGCGAAATCATCGGATGTAGATAAGGTAATTGGATTTAGTACTGGGGCAGATGATTATATTGTGAAGCCGTTCAGTAC
AATTGAATTTATAGCAAGAGTGAAAGCTCAATTAAGAAGGTATACATATTTCAATCAAAATGCTCCCCAAGTAATGGAAA
AGAAAATAAATATTAGAGGTTTAGAAATAGATGAAGTGTCGAGAACAGTAATGTTATATGGAGAGAGAATCAATCTTACG
AAAACTGAATATGATATTTTACACTTAATGGCAGCTGCAAGGAATCGTGTGTTCACAATTGAAGAAATATATGAGAGCGT
TTGGAACGAAAGAGCCTATGAAATTAATAATACAGTAATGGTTCATATTGCAAGATTGAGAAATAAAATTGAAGAGAATC
CAAAAGAACCGAAGTTTATACAAAATGTTTGGGGAGTCGGATATAAAATTGAAGATTAA

Upstream 100 bases:

>100_bases
TATAATTTAATCTGAAAATAAAGATTATTCAAGGTGTAAGGGTAGATTTGATTTATGATAAACTTAGATGTGGAATATAT
TTCAAAAAAGAGGTTTGGAA

Downstream 100 bases:

>100_bases
ATCATTACAAGGCATTAGAGCTAAGTTTTTTATCGCATTCATATGTAGCATCTTGTTAGCGACTGTAAGTATAATAGTGT
TTCAAATTTTGGTTGGAAAT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MEKNSILIVDDDKDIIQFINVNLKQEGFKVFSAHNGEEALEIINNNSIQLAILDIMMPQMDGIELCRRIREKHSLPIMFL
SAKSSDVDKVIGFSTGADDYIVKPFSTIEFIARVKAQLRRYTYFNQNAPQVMEKKINIRGLEIDEVSRTVMLYGERINLT
KTEYDILHLMAAARNRVFTIEEIYESVWNERAYEINNTVMVHIARLRNKIEENPKEPKFIQNVWGVGYKIED

Sequences:

>Translated_232_residues
MEKNSILIVDDDKDIIQFINVNLKQEGFKVFSAHNGEEALEIINNNSIQLAILDIMMPQMDGIELCRRIREKHSLPIMFL
SAKSSDVDKVIGFSTGADDYIVKPFSTIEFIARVKAQLRRYTYFNQNAPQVMEKKINIRGLEIDEVSRTVMLYGERINLT
KTEYDILHLMAAARNRVFTIEEIYESVWNERAYEINNTVMVHIARLRNKIEENPKEPKFIQNVWGVGYKIED
>Mature_232_residues
MEKNSILIVDDDKDIIQFINVNLKQEGFKVFSAHNGEEALEIINNNSIQLAILDIMMPQMDGIELCRRIREKHSLPIMFL
SAKSSDVDKVIGFSTGADDYIVKPFSTIEFIARVKAQLRRYTYFNQNAPQVMEKKINIRGLEIDEVSRTVMLYGERINLT
KTEYDILHLMAAARNRVFTIEEIYESVWNERAYEINNTVMVHIARLRNKIEENPKEPKFIQNVWGVGYKIED

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.8947368421053, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=33.920704845815, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=36.1233480176211, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=31.6017316017316, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=30.0884955752212, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=31.304347826087, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.0357142857143, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=32.7433628318584, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=33.920704845815, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=30.2127659574468, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.4561403508772, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=211, Percent_Identity=29.3838862559242, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=28.2608695652174, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=32.520325203252, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=31.4814814814815, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=136, Percent_Identity=28.6764705882353, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=130, Percent_Identity=34.6153846153846, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788905, Length=100, Percent_Identity=32, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27006; Mature: 27006

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNSILIVDDDKDIIQFINVNLKQEGFKVFSAHNGEEALEIINNNSIQLAILDIMMPQM
CCCCCEEEEECCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHCCCCEEEEEEEHHCCCC
DGIELCRRIREKHSLPIMFLSAKSSDVDKVIGFSTGADDYIVKPFSTIEFIARVKAQLRR
CHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHH
YTYFNQNAPQVMEKKINIRGLEIDEVSRTVMLYGERINLTKTEYDILHLMAAARNRVFTI
HHHCCCCCHHHHHHCCCCCCCCHHHHHCEEEEECCEECCCHHHHHHHHHHHHHCCCEEEH
EEIYESVWNERAYEINNTVMVHIARLRNKIEENPKEPKFIQNVWGVGYKIED
HHHHHHHHCCCCEEECCCCEEHHHHHHHHHHCCCCCCHHHHHHHCCCEEECC
>Mature Secondary Structure
MEKNSILIVDDDKDIIQFINVNLKQEGFKVFSAHNGEEALEIINNNSIQLAILDIMMPQM
CCCCCEEEEECCHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHCCCCEEEEEEEHHCCCC
DGIELCRRIREKHSLPIMFLSAKSSDVDKVIGFSTGADDYIVKPFSTIEFIARVKAQLRR
CHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHH
YTYFNQNAPQVMEKKINIRGLEIDEVSRTVMLYGERINLTKTEYDILHLMAAARNRVFTI
HHHCCCCCHHHHHHCCCCCCCCHHHHHCEEEEECCEECCCHHHHHHHHHHHHHCCCEEEH
EEIYESVWNERAYEINNTVMVHIARLRNKIEENPKEPKFIQNVWGVGYKIED
HHHHHHHHCCCCEEECCCCEEHHHHHHHHHHCCCCCCHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]