Click here to switch to the map view.

The map label for this gene is yciC [H]

Identifier: 218235691

GI number: 218235691

Start: 1682496

End: 1683683

Strand: Reverse

Name: yciC [H]

Synonym: BCB4264_A1776

Alternate gene names: 218235691

Gene position: 1683683-1682496 (Counterclockwise)

Preceding gene: 218232517

Following gene: 218231102

Centisome position: 31.07

GC content: 33.67

Gene sequence:

>1188_bases
ATGAAAAAAGTACCTATCACTGTATTAAGTGGTTTTTTAGGATCTGGAAAAACTACCTTACTACATCACATTTTGACTAA
TAAGAATAACTTAAAAGTAGCTGTTATCGTTAATGATATGAGCGAAGTAAACATTGATGCATCTCTTATAAAAAAGGGTG
GTTTTTCACGTACGGAGGAAAAACTAGTAGAAATTCAAAATGGCTGTATTTGTTGTACACTACGAGAAGATTTAATGATA
GAAGTGAATCGTCTTGTGGAAAATGGTGATATTGACTATATTATTATTGAATCTTCTGGTATAAGTGAGCCTATTCCAGT
TGCTCAAACGTTTACTTATACAGACGAAGTTCTTAACATTGATTTAACGAAAAATTGTCGCCTCGATACGATGGTTACAG
TTGTAGATGCAAATAGATTTTGGGATGATTTTGCAGATGGAGAAAGTTTATTAGACCGAAAACAAGCAATCGATGAGAAT
GATACCCGGGAAGTTATTGATTTATTAATAGATCAAATTGAGTTTGCAAACGTAATTATTCTTAATAAGATAGATTTGCT
AGAAAAAGAAGATGTGATAGAGCTTCATCATTTACTAAAAAAATTAAATCCTAATGCAAAAGTTCTTGAATCTTCGTTTA
GCAAAGTACCATTACAAGAAATTTTAAACACAAATCTATTTAATTATGAAGAAGCCAGTCAATCGGCCGGCTGGATACAA
GAATTAAATAGTGACCATCATACACCGGAAACGGAAGAATACGGTATCAATTCCTTTGTTTACCGCCGCAAATATCCTTT
CTATCCCAAGCGCCTTATGAATTGGCTAGAAAAATGGCCTTTAGATGTTGTAAGAGCGAAAGGATTCTTCTGGCTGGCAT
CTCGTAATAATATGATAGGGCTTCTATCTCAAGCAGGTTCCTCTATTACAATTCAAGGAGCCGGTGAGTGGATAGCGGCA
TTACCTGAAACTGAAAGAAATCAAATGATTACAGAAGAACCAGAAGTATTGAAAAACTGGGATAAACAATATGGAGATCG
AATAACCGAACTCGTATTTATCGGAATTGATATGAACCGTTCTTTAATTGAACAATCATTAGATAGTTGTCTATTAACAG
AGAAAGAAATGAAACAAAACTGGAATACATTTATTGATCCTATCCCGGCTTTTACTTATACTTCATAA

Upstream 100 bases:

>100_bases
CTATTCTTAAATCGTAATCATTATGATTTATTATTGATTTTTCTTTTCCCATCGTTTAATATAAAACGTAATCATTACGA
TTTAAAGGAGAGATCATTTC

Downstream 100 bases:

>100_bases
CAATTAATAAAAGGCTTCAGTAGAATGAAGCCTTTTTACTTTATAGCACTCTTATTTAATAGGTTTGCTTTAATTATAAA
TACAATTGTACCTAAAACAA

Product: putative cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKKVPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLMI
EVNRLVENGDIDYIIIESSGISEPIPVAQTFTYTDEVLNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAIDEN
DTREVIDLLIDQIEFANVIILNKIDLLEKEDVIELHHLLKKLNPNAKVLESSFSKVPLQEILNTNLFNYEEASQSAGWIQ
ELNSDHHTPETEEYGINSFVYRRKYPFYPKRLMNWLEKWPLDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAA
LPETERNQMITEEPEVLKNWDKQYGDRITELVFIGIDMNRSLIEQSLDSCLLTEKEMKQNWNTFIDPIPAFTYTS

Sequences:

>Translated_395_residues
MKKVPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLMI
EVNRLVENGDIDYIIIESSGISEPIPVAQTFTYTDEVLNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAIDEN
DTREVIDLLIDQIEFANVIILNKIDLLEKEDVIELHHLLKKLNPNAKVLESSFSKVPLQEILNTNLFNYEEASQSAGWIQ
ELNSDHHTPETEEYGINSFVYRRKYPFYPKRLMNWLEKWPLDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAA
LPETERNQMITEEPEVLKNWDKQYGDRITELVFIGIDMNRSLIEQSLDSCLLTEKEMKQNWNTFIDPIPAFTYTS
>Mature_395_residues
MKKVPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLMI
EVNRLVENGDIDYIIIESSGISEPIPVAQTFTYTDEVLNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAIDEN
DTREVIDLLIDQIEFANVIILNKIDLLEKEDVIELHHLLKKLNPNAKVLESSFSKVPLQEILNTNLFNYEEASQSAGWIQ
ELNSDHHTPETEEYGINSFVYRRKYPFYPKRLMNWLEKWPLDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAA
LPETERNQMITEEPEVLKNWDKQYGDRITELVFIGIDMNRSLIEQSLDSCLLTEKEMKQNWNTFIDPIPAFTYTS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=260, Percent_Identity=31.1538461538462, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI126722884, Length=260, Percent_Identity=30.7692307692308, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI146231952, Length=398, Percent_Identity=26.3819095477387, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI148727351, Length=260, Percent_Identity=30.3846153846154, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI223941779, Length=227, Percent_Identity=31.7180616740088, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI223941776, Length=249, Percent_Identity=30.1204819277108, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI119120938, Length=137, Percent_Identity=36.4963503649635, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI87082430, Length=369, Percent_Identity=27.10027100271, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788499, Length=211, Percent_Identity=30.8056872037915, Blast_Score=85, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=235, Percent_Identity=30.6382978723404, Blast_Score=110, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 45184; Mature: 45184

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEE
CCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHCCCCCHHHH
KLVEIQNGCICCTLREDLMIEVNRLVENGDIDYIIIESSGISEPIPVAQTFTYTDEVLNI
HHHHHCCCEEEEEECHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEE
DLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAIDENDTREVIDLLIDQIEFANVII
EECCCCCCCEEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEE
LNKIDLLEKEDVIELHHLLKKLNPNAKVLESSFSKVPLQEILNTNLFNYEEASQSAGWIQ
EECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHH
ELNSDHHTPETEEYGINSFVYRRKYPFYPKRLMNWLEKWPLDVVRAKGFFWLASRNNMIG
HHCCCCCCCCCHHCCCCHHHEECCCCCCHHHHHHHHHHCCHHHEECCCEEEEECCCCEEE
LLSQAGSSITIQGAGEWIAALPETERNQMITEEPEVLKNWDKQYGDRITELVFIGIDMNR
EHCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCH
SLIEQSLDSCLLTEKEMKQNWNTFIDPIPAFTYTS
HHHHHHHHHHHCCHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MKKVPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEE
CCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHCCCCCHHHH
KLVEIQNGCICCTLREDLMIEVNRLVENGDIDYIIIESSGISEPIPVAQTFTYTDEVLNI
HHHHHCCCEEEEEECHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEE
DLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAIDENDTREVIDLLIDQIEFANVII
EECCCCCCCEEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEE
LNKIDLLEKEDVIELHHLLKKLNPNAKVLESSFSKVPLQEILNTNLFNYEEASQSAGWIQ
EECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHH
ELNSDHHTPETEEYGINSFVYRRKYPFYPKRLMNWLEKWPLDVVRAKGFFWLASRNNMIG
HHCCCCCCCCCHHCCCCHHHEECCCCCCHHHHHHHHHHCCHHHEECCCEEEEECCCCEEE
LLSQAGSSITIQGAGEWIAALPETERNQMITEEPEVLKNWDKQYGDRITELVFIGIDMNR
EHCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEEECCCH
SLIEQSLDSCLLTEKEMKQNWNTFIDPIPAFTYTS
HHHHHHHHHHHCCHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]