| Definition | Bacillus cereus B4264, complete genome. |
|---|---|
| Accession | NC_011725 |
| Length | 5,419,036 |
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The map label for this gene is fadH [H]
Identifier: 218235486
GI number: 218235486
Start: 4006669
End: 4007439
Strand: Reverse
Name: fadH [H]
Synonym: BCB4264_A4095
Alternate gene names: 218235486
Gene position: 4007439-4006669 (Counterclockwise)
Preceding gene: 218232962
Following gene: 218232024
Centisome position: 73.95
GC content: 39.69
Gene sequence:
>771_bases ATGTATGTGAAAGAAAAGGTAGTTATTATAACAGGTGGATCGAGTGGAATGGGAAAAGGAATGGCGACTCGCTTTGCAAA AGAAGGGGCACGAGTTGTTATTACAGGACGTACAAAAGAAAAACTAGAGGAAACAAAGTTGGAAATTGAACAATTTCCAG GGCAAGTATTACCTGTACAAATGGATGTAAGAAATACGGATGACATTCAGAAAATGATTGAACAGATTGATGAGAAGTTT GGTCGAATTGATGTTTTAATAAATAATGCAGCTGGAAACTTTATTTGTCCAGCAGAAGATTTATCCGTGAATGGCTGGAA TTCGGTCATTAATATTGTATTAAACGGTACATTTTACTGTAGCCATGCTGTCGGAAAATATTGGATTGAAAAAGGTATAA AAGGGAATATCATTAATATGGTAGCAACATATGCATGGGATGCAGGTCCAGGAGTTATTCATTCGGCTGCAGCGAAGGCA GGAGTATTAGCGATGACGAAGACGCTCGCTGTTGAGTGGGGACGTAAATATGGAATACGAGTTAACGCTATCGCTCCAGG ACCAATTGAACGTACGGGCGGTGCTGATAAATTATGGATTTCAGAAGAAATGGCTAAGCGTACGATACAAAGTGTTCCGC TTGGAAGGCTGGGTACGCCAGAAGAAATCGCTGGTCTAGCTTATTATTTATGCTCAGATGAAGCTGCGTACATAAATGGA ACTTGCATGACAATGGATGGAGGACAACATTTACATCAATATCCATTTTAA
Upstream 100 bases:
>100_bases AAGAAAGTTCTTTACATTAAAATATCAGAAAAGTTTAAAAATATAAAGATTTCTATTAAATAAAGTGATAAAATGAATGT GTATTCATTTTTTGGAGGGG
Downstream 100 bases:
>100_bases AAGGGATAAAAAAATGAATGTTTGATTCATTTTTTTACGGTTAAATGTGACGGAATTGTGACATATGAAAGAAAAGTGTT TACAAGAGGTCATATATACG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MYVKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEETKLEIEQFPGQVLPVQMDVRNTDDIQKMIEQIDEKF GRIDVLINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYCSHAVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKA GVLAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYING TCMTMDGGQHLHQYPF
Sequences:
>Translated_256_residues MYVKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEETKLEIEQFPGQVLPVQMDVRNTDDIQKMIEQIDEKF GRIDVLINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYCSHAVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKA GVLAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYING TCMTMDGGQHLHQYPF >Mature_256_residues MYVKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEETKLEIEQFPGQVLPVQMDVRNTDDIQKMIEQIDEKF GRIDVLINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYCSHAVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKA GVLAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYING TCMTMDGGQHLHQYPF
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=42.4107142857143, Blast_Score=175, Evalue=3e-44, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=39.4422310756972, Blast_Score=167, Evalue=9e-42, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=34.3629343629344, Blast_Score=167, Evalue=1e-41, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=29.0983606557377, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=29.9610894941634, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI59889578, Length=240, Percent_Identity=32.9166666666667, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=31.2252964426877, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=25, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=29.5546558704453, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=25.609756097561, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=25.6, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI209862901, Length=221, Percent_Identity=27.1493212669683, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI19923983, Length=221, Percent_Identity=27.1493212669683, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=28.6307053941909, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=27.4809160305344, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI40254986, Length=200, Percent_Identity=32.5, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503817, Length=196, Percent_Identity=29.5918367346939, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4504505, Length=240, Percent_Identity=28.75, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=28.4263959390863, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=25.1908396946565, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1789208, Length=243, Percent_Identity=32.5102880658436, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=33.4600760456274, Blast_Score=117, Evalue=7e-28, Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=32.156862745098, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=30.4526748971193, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=30.8641975308642, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=29.3650793650794, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=26.953125, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1787820, Length=243, Percent_Identity=28.8065843621399, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=23.921568627451, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1787526, Length=250, Percent_Identity=25.2, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=25, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=27.0491803278689, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787545, Length=261, Percent_Identity=25.6704980842912, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=41.40625, Blast_Score=197, Evalue=6e-51, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=41.5686274509804, Blast_Score=195, Evalue=2e-50, Organism=Caenorhabditis elegans, GI17561272, Length=240, Percent_Identity=42.9166666666667, Blast_Score=182, Evalue=2e-46, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=32.4427480916031, Blast_Score=121, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=31.9391634980989, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=30.3030303030303, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=35.7414448669202, Blast_Score=114, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=32.3076923076923, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.4090909090909, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=32.5396825396825, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=31.9230769230769, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=33.0798479087452, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=31.8352059925094, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=30.2788844621514, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=29.9242424242424, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=32.1969696969697, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.188679245283, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=29.7397769516729, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.8804780876494, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=30.241935483871, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28.4, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=25.7936507936508, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=28.6259541984733, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=31.0861423220974, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.9245283018868, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=25, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=27.8195488721804, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=30.2564102564103, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=27.6679841897233, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17558628, Length=195, Percent_Identity=32.8205128205128, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI71997099, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.6, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17555612, Length=229, Percent_Identity=27.5109170305677, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI86565303, Length=159, Percent_Identity=28.9308176100629, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=37.109375, Blast_Score=148, Evalue=9e-37, Organism=Saccharomyces cerevisiae, GI6322861, Length=261, Percent_Identity=29.5019157088123, Blast_Score=82, Evalue=6e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=237, Percent_Identity=30.379746835443, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=35.8267716535433, Blast_Score=134, Evalue=6e-32, Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=33.0739299610895, Blast_Score=126, Evalue=1e-29, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=33.7301587301587, Blast_Score=124, Evalue=4e-29, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=31.2, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=28.6290322580645, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=24.6913580246914, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI17737361, Length=261, Percent_Identity=28.735632183908, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=28.0632411067194, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21357673, Length=191, Percent_Identity=31.413612565445, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24580925, Length=194, Percent_Identity=27.319587628866, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI18859837, Length=243, Percent_Identity=27.5720164609054, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=24.3654822335025, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=26.1780104712042, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 27903; Mature: 27903
Theoretical pI: Translated: 6.92; Mature: 6.92
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYVKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEETKLEIEQFPGQVLPVQ CCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEE MDVRNTDDIQKMIEQIDEKFGRIDVLINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYC EECCCCHHHHHHHHHHHHHHCEEEEEEECCCCCEECCCCCCCCCCHHHEEEEEECCEEEE SHAVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGVLAMTKTLAVEWGRKYGIR HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE VNAIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYING EEEECCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCEEECC TCMTMDGGQHLHQYPF EEEEECCCCCCCCCCC >Mature Secondary Structure MYVKEKVVIITGGSSGMGKGMATRFAKEGARVVITGRTKEKLEETKLEIEQFPGQVLPVQ CCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEE MDVRNTDDIQKMIEQIDEKFGRIDVLINNAAGNFICPAEDLSVNGWNSVINIVLNGTFYC EECCCCHHHHHHHHHHHHHHCEEEEEEECCCCCEECCCCCCCCCCHHHEEEEEECCEEEE SHAVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGVLAMTKTLAVEWGRKYGIR HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE VNAIAPGPIERTGGADKLWISEEMAKRTIQSVPLGRLGTPEEIAGLAYYLCSDEAAYING EEEECCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCEEECC TCMTMDGGQHLHQYPF EEEEECCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]