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The map label for this gene is dnaC [H]

Identifier: 218235480

GI number: 218235480

Start: 968385

End: 969671

Strand: Direct

Name: dnaC [H]

Synonym: BCB4264_A0983

Alternate gene names: 218235480

Gene position: 968385-969671 (Clockwise)

Preceding gene: 218236086

Following gene: 218230960

Centisome position: 17.87

GC content: 43.2

Gene sequence:

>1287_bases
ATGAGTATTCAAAATGTGGAGGCGGAAAAGACGGTGTTAGGTTCTCTACTACTTGATGGAGAGCTTATTAAGGAGTGCCG
TTTGACGGAGCAGTATTTTTCTATGCCAGTACATAAGTCTATATTTCAGTTAATGCGAAAGATGGAAGGAGAGGGGCAAC
CGATTGATCTTGTGACTTTCACTTCTAGGTTGGACCCGAATTTTTTGAAGGGCATCGGGGGAATGGAGTATTTTATAGGG
TTAATGGATGGTGTGCCTACTACTAGCAATTTCTCTTATTATGAGGGGCTTGTTCGAGGTGCGTGGAAAATGTATCAGGC
CGGTGTTCTCGGGCACAAGATGGGAGAGCGTCTTATTGCGGAGAAGAGTGAGAAAGTTATCGGTGAGACGATTACGGCAC
TTTGTGAGTTAGAGGAGAAAGACTCTGTATGTGAGTTTGATTTGAAGGATGCGCTAGTTGATTTATATGAAGAGCTTCAT
CAAGATGTGAAGGAGATTACTGGTATTGAGAGTGGTTATACATCGTTAAATAAAATGACGTGCGGATTGCAGGAAGGTGA
TTTTGTCGTTCTTGGTGCGCGCCCTTCTATGGGGAAGACTGCGTTTGCGCTTAATGTTGGATTGCATGCGGCGAAGTCTG
GAGCGGCGGTTGGATTGTTTTCGTTAGAGATGAGTAGTAAGCAATTGTTAAAAAGGATGGCATCTTGCGTAGGTGAAGTG
TCAGGAGGTAGGCTGAAAAATCCGAAGCATCGTTTTGCGATGGAAGATTGGGAGAAGGTAAGTAAGGCGTTTGCGGAGAT
TGGTGAGTTGCCATTTGAGATTTACGACAATGCAGGCGTTACGGTACAAGATATTTGGATGCAAACTCGTAAGTTAAAGA
GGAAGCACGGTGATAAAAAGATTTTAATTATTGTAGATTACTTGCAGCTTATTACGGGCGATCCGAAGCATAAGGGCAAT
CGATTTCAAGAAATTAGTGAGATTTCTCGTAAGCTTAAGTTATTAGCACGTGAGTTAAATGTTTGTGTAGTAGCGTTATC
ACAGTTATCTCGTTCTGTAGAGTCGCGGCAAGATAAGCGTCCGCTTTTATCAGATTTAAGAGAGACGGGCCAAATTGAGC
AAGATGCGGATGTCATTATGCTTATGTATCGAGAGGATTATTACGATAAGGAAACGATGCAGAAAGAGATGACGGAGATT
CATGTAGCGAAGCATCGGAATGGACCTGTGGGGAGTTTTAAGCTGAGGTTTTTGAAGGAGTTTGGACGGTTTGTGGAGGG
GGAATAG

Upstream 100 bases:

>100_bases
GGGAGACGGAGGAGTTTTTGGCGAGGTGTGAGGAGTGGGAGAAGAATGCGCCATCTGAGGAAGAGTTGCAGCGCTTTTTA
GCGGAGCGCGGGTGGCGTCC

Downstream 100 bases:

>100_bases
TTGAAAGACTTGAGTATGACTTTGCAAATAAAATAAAGCATAAGTGTTCTATTGCATTCACTTATGCTTTATTCTTTGAT
TCTTTCAATATACTTCTTAT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRLDPNFLKGIGGMEYFIG
LMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKVIGETITALCELEEKDSVCEFDLKDALVDLYEELH
QDVKEITGIESGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEV
SGGRLKNPKHRFAMEDWEKVSKAFAEIGELPFEIYDNAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKHKGN
RFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEMTEI
HVAKHRNGPVGSFKLRFLKEFGRFVEGE

Sequences:

>Translated_428_residues
MSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRLDPNFLKGIGGMEYFIG
LMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKVIGETITALCELEEKDSVCEFDLKDALVDLYEELH
QDVKEITGIESGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEV
SGGRLKNPKHRFAMEDWEKVSKAFAEIGELPFEIYDNAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKHKGN
RFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEMTEI
HVAKHRNGPVGSFKLRFLKEFGRFVEGE
>Mature_427_residues
SIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTFTSRLDPNFLKGIGGMEYFIGL
MDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKVIGETITALCELEEKDSVCEFDLKDALVDLYEELHQ
DVKEITGIESGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEVS
GGRLKNPKHRFAMEDWEKVSKAFAEIGELPFEIYDNAGVTVQDIWMQTRKLKRKHGDKKILIIVDYLQLITGDPKHKGNR
FQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEMTEIH
VAKHRNGPVGSFKLRFLKEFGRFVEGE

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=442, Percent_Identity=38.0090497737557, Blast_Score=265, Evalue=5e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 48337; Mature: 48205

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEE
TSRLDPNFLKGIGGMEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIA
CCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKSEKVIGETITALCELEEKDSVCEFDLKDALVDLYEELHQDVKEITGIESGYTSLNKMT
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
CGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEV
CCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHC
SGGRLKNPKHRFAMEDWEKVSKAFAEIGELPFEIYDNAGVTVQDIWMQTRKLKRKHGDKK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCE
ILIIVDYLQLITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKR
EEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEMTEIHVAKHRNGPVGSFKLRFLKE
HHHHHHHHCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
FGRFVEGE
HHHHCCCC
>Mature Secondary Structure 
SIQNVEAEKTVLGSLLLDGELIKECRLTEQYFSMPVHKSIFQLMRKMEGEGQPIDLVTF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEE
TSRLDPNFLKGIGGMEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIA
CCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKSEKVIGETITALCELEEKDSVCEFDLKDALVDLYEELHQDVKEITGIESGYTSLNKMT
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
CGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRMASCVGEV
CCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHC
SGGRLKNPKHRFAMEDWEKVSKAFAEIGELPFEIYDNAGVTVQDIWMQTRKLKRKHGDKK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCE
ILIIVDYLQLITGDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKR
EEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLLSDLRETGQIEQDADVIMLMYREDYYDKETMQKEMTEIHVAKHRNGPVGSFKLRFLKE
HHHHHHHHCCCCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
FGRFVEGE
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]