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The map label for this gene is yrkH [H]

Identifier: 218235004

GI number: 218235004

Start: 803455

End: 804585

Strand: Direct

Name: yrkH [H]

Synonym: BCB4264_A0831

Alternate gene names: 218235004

Gene position: 803455-804585 (Clockwise)

Preceding gene: 218235754

Following gene: 218231893

Centisome position: 14.83

GC content: 36.43

Gene sequence:

>1131_bases
ATGAATGTTAAACCGTTACAAGCAAAAGATGTTGCAGAGAAAGTTTTATTCGGAGAGTTATTCATTTTAGATGTTCGTAA
TGAGGCGGATTATGAAGATTGGAAAATTGAAGGGAAACAAGTTTCTTCTATTAATAGACCTTACTTTGACTTGTTAGATG
GTGTAGATCATATTGTAAGTGAATTACCTAAAGATAAAGATGTTTTAGTAGTATGTGCAAAAGAAGGGTCTTCTATATTT
GTGGCAGAGCAATTAACAGAGGCTGGATTAGAAAATATTTATTATTTAGCTGGTGGCATGAAGGCTTGGAGTGAATATGT
AAAGCCTATAAAAGTTGGAGATTTAAAAAATGGTGGAAGTATGTATCAGTTTAACCGCCTTGGAAAAGGCTGTTTATCTT
ATATGGTCGTTTCAAATGGTGAAGCAGCAGTTATTGATGCAGTAAGAACAGCCGAGGCATATGAAGAATTTGCGAAAGAG
CATGGCGTTACGATTACGAATGTAATGGATACACATTTACATGCAGACCATATTTCCGGAGGACGTAAGTTAGCGGAAAA
GGTAGGTGGTACGTATTGGTTACCACCAAAAGATGCAGAGGAAGTTGTTTTCTCATACGAACCGCTTGTTGAAGGATCTG
TTATTACGGTGGGGGGTACTAAAATTGTAATTGACGCATTATACTCACCAGGGCATACGATTGGAAGTACGTCATTCATT
GTAGATGATTCTTATTTATTATCAGGCGATATTTTATTTGTAGATTCAATTGGGCGTCCTGATCTTGCTGGTAAGGCTGA
AGATTGGGTAAGTGATTTACGTAATACTTTGTATAGCCGATATAAAGAGCTATCTCAAAATTTAGTTGTGTTACCGGCTC
ATTATTCAAAAATAAGTGAAATGAACGAAAGTGGTATTGTTAGTGCAAAATTAAAAGATTTATTTGAGCATAATGCAGGA
TTAAATATTGAGGATGAGGGAGAGTTCCGTAAAGTTGTAACAGAAAACTTACCACCTCAGCCAAATGCATATGAAGAAAT
TCGTCAAACCAATATGGGTAAAATTCACCCAAGTGTGGATAAAGAGCGTGAAATGGAGATTGGTCCAAATCGTTGTGCAG
TGCACGAATAA

Upstream 100 bases:

>100_bases
ATGCAAATGTGAAAAATGTCATTCCAGGCATGTTAGAGTGGCAAGGGAATATAGAGAAATAAATTTTTTTGAATAAAAAT
ATACCTATGGGGGTAATAAG

Downstream 100 bases:

>100_bases
TGAAATAAATAAAAAATGGAGGAATTGATGATGAATATAAAACAAGTGTTAGATGCGAAAGGTTTAGCATGTCCAATGCC
GATTGTAAGAACAAAGAGAG

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNVKPLQAKDVAEKVLFGELFILDVRNEADYEDWKIEGKQVSSINRPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAVRTAEAYEEFAKE
HGVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIVIDALYSPGHTIGSTSFI
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLVVLPAHYSKISEMNESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDKEREMEIGPNRCAVHE

Sequences:

>Translated_376_residues
MNVKPLQAKDVAEKVLFGELFILDVRNEADYEDWKIEGKQVSSINRPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAVRTAEAYEEFAKE
HGVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIVIDALYSPGHTIGSTSFI
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLVVLPAHYSKISEMNESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDKEREMEIGPNRCAVHE
>Mature_376_residues
MNVKPLQAKDVAEKVLFGELFILDVRNEADYEDWKIEGKQVSSINRPYFDLLDGVDHIVSELPKDKDVLVVCAKEGSSIF
VAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGSMYQFNRLGKGCLSYMVVSNGEAAVIDAVRTAEAYEEFAKE
HGVTITNVMDTHLHADHISGGRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIVIDALYSPGHTIGSTSFI
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLVVLPAHYSKISEMNESGIVSAKLKDLFEHNAG
LNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVDKEREMEIGPNRCAVHE

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1787158, Length=173, Percent_Identity=28.3236994219653, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330176, Length=166, Percent_Identity=30.7228915662651, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 41665; Mature: 41665

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKPLQAKDVAEKVLFGELFILDVRNEADYEDWKIEGKQVSSINRPYFDLLDGVDHIVS
CCCCCCCHHHHHHHHHHCEEEEEEECCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHH
ELPKDKDVLVVCAKEGSSIFVAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGS
HCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHEEEECCCHHHHHHHCCCEEECCCCCCCC
MYQFNRLGKGCLSYMVVSNGEAAVIDAVRTAEAYEEFAKEHGVTITNVMDTHLHADHISG
CHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCC
GRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIVIDALYSPGHTIGSTSFI
HHHHHHHCCCEEECCCCCHHHHHEECCCCCCCCEEEECCCEEEEEECCCCCCCCCCEEEE
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLVVLPAHYSKISE
EECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHH
MNESGIVSAKLKDLFEHNAGLNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVD
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
KEREMEIGPNRCAVHE
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVKPLQAKDVAEKVLFGELFILDVRNEADYEDWKIEGKQVSSINRPYFDLLDGVDHIVS
CCCCCCCHHHHHHHHHHCEEEEEEECCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHH
ELPKDKDVLVVCAKEGSSIFVAEQLTEAGLENIYYLAGGMKAWSEYVKPIKVGDLKNGGS
HCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHEEEECCCHHHHHHHCCCEEECCCCCCCC
MYQFNRLGKGCLSYMVVSNGEAAVIDAVRTAEAYEEFAKEHGVTITNVMDTHLHADHISG
CHHHHHHHHHHHHEEEECCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCC
GRKLAEKVGGTYWLPPKDAEEVVFSYEPLVEGSVITVGGTKIVIDALYSPGHTIGSTSFI
HHHHHHHCCCEEECCCCCHHHHHEECCCCCCCCEEEECCCEEEEEECCCCCCCCCCEEEE
VDDSYLLSGDILFVDSIGRPDLAGKAEDWVSDLRNTLYSRYKELSQNLVVLPAHYSKISE
EECCEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHH
MNESGIVSAKLKDLFEHNAGLNIEDEGEFRKVVTENLPPQPNAYEEIRQTNMGKIHPSVD
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCC
KEREMEIGPNRCAVHE
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]