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The map label for this gene is appC [H]

Identifier: 218234952

GI number: 218234952

Start: 218614

End: 219534

Strand: Direct

Name: appC [H]

Synonym: BCB4264_A0247

Alternate gene names: 218234952

Gene position: 218614-219534 (Clockwise)

Preceding gene: 218235203

Following gene: 218234473

Centisome position: 4.03

GC content: 36.16

Gene sequence:

>921_bases
ATGGAGACTGTTACAGTAATTACAGAAAAAAAAGAAAAAAAGAGAAGAAATGAATCATCACCATGGCGACAAGCTTTTAA
AAAGATAAAGAAAAATAAGATGGCACTTGTAGGGTTTTATGCATTAATTTTTATGTTTTTATTTTGTTTTATCGGTCCGT
TCTTTTCTCCATATGCATCAGGAAAAATACAAGTTGCGCTCATTAACAAACCACCTAGTTTTTCTCATTGGCTTGGTACA
GATCAATTAGGAAGAGATATTTTAACAAGGCTTATGCAAGCGGGACGTATTTCATTAACCATTGGTTTAGCTTCAATGGT
TTTATCGGTTATACTTGGAGCTTTATTAGGAGCGATTGCAGGTTTTTATCGTGGTATTGTGGACAATATTATTATGCGAC
TTGCAGATATTTTAATGTCGATGCCAGGATTACCGTTACTTATTATAATGGGTGCGATTTTATCAGAGTGGAAAGTACCG
TCTGATTATCGTTTGTATGTCATTATGATTATTTTAAGTTTAGTAGGTTGGCCAGGGCTTGCACGCCTTGTAAGAGGGCA
AATTTTATCACTTAGGGAGCAAGCATTTATGCAAGCTGCGGATGTGTTAGGAATAAAAGATTACCGGAAAATTATATATC
ACTTAATACCTAATGTTTTACCAATTTTAATTGTCGTATCTACATTAGGTGTTGCAGGTTCTATTTTGGGAGAATCCGCA
CTAAGTTACTTAGGTCTCGGAGTCGTTCCACCTACACCATCATGGGGGAACATGATTAGCGCAGCTAACTCATTAATCGA
TTTCCAAAAGCGTCCATGGTTATGGATTCCGCCTGGTTTTGCAATTTTTATAACAGTTGTATCAATTAATTTACTTGGTG
ATGCACTTCGTGATGCATTAGATCCAAAGATGAGACGGTAG

Upstream 100 bases:

>100_bases
CGATGTTTCTTTCTTGTTTAACAATCGTTTCAAACTTTTTAGCAGATATCGTATATGCAGTTGTTGATCCAAGAATTCGG
TTGAAGTAAGGGGCAAAGAA

Downstream 100 bases:

>100_bases
GTGAGGAGATATGAGTAAAGCAGTAGTAGAGCTGAAAGATTTACAAACACACTTTCAGACAGAAGAAGGGACAGTAAAAG
CTGTGAATCATGTTAGTTTT

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
METVTVITEKKEKKRRNESSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHWLGT
DQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVP
SDYRLYVIMIILSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESA
LSYLGLGVVPPTPSWGNMISAANSLIDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR

Sequences:

>Translated_306_residues
METVTVITEKKEKKRRNESSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHWLGT
DQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVP
SDYRLYVIMIILSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESA
LSYLGLGVVPPTPSWGNMISAANSLIDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR
>Mature_306_residues
METVTVITEKKEKKRRNESSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHWLGT
DQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVP
SDYRLYVIMIILSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESA
LSYLGLGVVPPTPSWGNMISAANSLIDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=287, Percent_Identity=35.191637630662, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1787498, Length=307, Percent_Identity=36.4820846905537, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1787760, Length=302, Percent_Identity=31.7880794701987, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789964, Length=308, Percent_Identity=37.012987012987, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789889, Length=248, Percent_Identity=39.5161290322581, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1788505, Length=235, Percent_Identity=32.3404255319149, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787549, Length=285, Percent_Identity=29.8245614035088, Blast_Score=117, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33915; Mature: 33915

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVTVITEKKEKKRRNESSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYAS
CCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIA
CEEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHH
GFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVPSDYRLYVIMIILSLVGWPGL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHH
ARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSYLGLGVVPPTPSWGNMISAANSLIDFQKRPWLWIPPGFAIFITVVSINLLGDALRDAL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHC
DPKMRR
CCCCCC
>Mature Secondary Structure
METVTVITEKKEKKRRNESSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYAS
CCCEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIA
CEEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHH
GFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVPSDYRLYVIMIILSLVGWPGL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHH
ARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSYLGLGVVPPTPSWGNMISAANSLIDFQKRPWLWIPPGFAIFITVVSINLLGDALRDAL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHC
DPKMRR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]