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The map label for this gene is trpB [H]

Identifier: 218234944

GI number: 218234944

Start: 1256707

End: 1257900

Strand: Direct

Name: trpB [H]

Synonym: BCB4264_A1296

Alternate gene names: 218234944

Gene position: 1256707-1257900 (Clockwise)

Preceding gene: 218231595

Following gene: 218235176

Centisome position: 23.19

GC content: 40.7

Gene sequence:

>1194_bases
ATGAACTACGCATATCCAGATGAAAAAGGACATTACGGTATATACGGAGGACGATACGTTCCAGAAACGTTAATGCAATC
TGTACTAGAACTAGAAGAAGCATATAAAGAAGCGATGCAAGATGAAGCATTTCAAAAGGAATTAAATCATTATTTAAAAA
CGTACGTCGGAAGAGAAACACCGCTTTATTTCGCTGAAAATCTGACGAAGTATTGCGGAGGTGCAAAGATTTATTTAAAA
CGTGAAGATTTGAACCATACAGGAGCTCATAAAATTAACAATACAATCGGTCAGGCACTACTTGCAGTGCGAATGGGCAA
GAAAAAAGTTGTCGCTGAAACAGGAGCTGGACAACACGGAGTTGCAACAGCTACTGTATGTGCTCTTCTCGGATTAGAAT
GCGTCATTTTTATGGGAGAAGAAGATGTAAGACGTCAAAAATTAAATGTGTTCCGAATGGAATTACTCGGAGCGAAAGTA
GAAAGTGTAGCGGCAGGTAGTGGTACATTAAAAGATGCGGTAAACGAGGCGCTTCGTTACTGGGTTTCACATGTGCATGA
TACGCACTACATTATGGGATCTGTTCTCGGACCACATCCATTCCCGCAAATTGTACGTGATTTCCAAAGTGTAATTGGAA
ATGAAACGAAAAAACAATATGAGGCGTTAGAAGGAAAGTTACCAGAAGCAGTCGTTGCTTGTATTGGCGGTGGCAGTAAT
GCGATGGGAATGTTTTATCCATTTGTACATGATGAAGAAGTTGCTCTTTACGGCGTAGAAGCAGCTGGAAAAGGCGTTCA
TACAGAAAAGCATGCAGCAACTTTAACGAAAGGAAGCGTTGGCGTTCTCCACGGATCAATGATGTATCTTCTGCAAAACG
AAGAAGGACAAATTCAAGAAGCACACTCTATTTCAGCAGGACTTGATTATCCAGGTGTTGGTCCAGAACATAGCTTGCTA
AAAGATATTGGCCGCGTTTCTTATCATTCGATAACAGACGAAGAAGCATTAGAAGCATTTCAATTATTAACGAAAAAAGA
AGGCATTATCCCGGCGTTAGAAAGCTCGCATGCTGTCGCATACGCATTAAAATTAGCGCCGCAAATGAAGAAAGATGAAG
GGCTTGTCATTTGTTTATCTGGCCGCGGTGATAAAGATGTAGAGAGTATAAAACGTTATATGGAAGAGGTGTAA

Upstream 100 bases:

>100_bases
GGCCATACATGGTCGATGTGAGCAGCGGAGTAGAGACAGAAGGAAAGAAAGATGTAGAGAAAATAAAACAATTTATTATA
AAAGCGAAGGAGTGTTCCAA

Downstream 100 bases:

>100_bases
AAAATGGGAGTAGAAAAAATTAAAGCAGCGTTTGAAAATGGAAAGAAAGCATTTATTCCGTACGTAATGGGCGGAGATGG
CGGCTTTGAAAAATTAAAAG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMQDEAFQKELNHYLKTYVGRETPLYFAENLTKYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDEEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV

Sequences:

>Translated_397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMQDEAFQKELNHYLKTYVGRETPLYFAENLTKYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDEEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV
>Mature_397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMQDEAFQKELNHYLKTYVGRETPLYFAENLTKYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDEEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=54.8556430446194, Blast_Score=421, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6321412, Length=388, Percent_Identity=57.9896907216495, Blast_Score=473, Evalue=1e-134,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43583; Mature: 43583

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMQDEAFQKELNHYLKTYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLYFAENLTKYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHG
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
VATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRY
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCC
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQE
CCCEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHH
AHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDEEALEAFQLLTKKEGIIPALESSHAVA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMQDEAFQKELNHYLKTYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PLYFAENLTKYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHG
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
VATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRY
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSN
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCC
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQE
CCCEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHH
AHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDEEALEAFQLLTKKEGIIPALESSHAVA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA